Detailed information    

insolico Bioinformatically predicted

Overview

Name   rexA   Type   Machinery gene
Locus tag   ST4145_RS07950 Genome accession   NZ_CP065492
Coordinates   1545436..1549089 (-) Length   1217 a.a.
NCBI ID   WP_024010071.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain 4145     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1540436..1554089
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ST4145_RS07930 (ST4145_07855) proB 1540831..1541634 (-) 804 WP_014608676.1 glutamate 5-kinase -
  ST4145_RS07935 (ST4145_07860) - 1541755..1543344 (-) 1590 WP_014608677.1 ABC transporter permease -
  ST4145_RS07940 (ST4145_07865) - 1543347..1544078 (-) 732 WP_002891761.1 ABC transporter ATP-binding protein -
  ST4145_RS07945 (ST4145_07870) - 1544353..1545084 (+) 732 WP_024010070.1 DUF554 domain-containing protein -
  ST4145_RS07950 (ST4145_07875) rexA 1545436..1549089 (-) 3654 WP_024010071.1 helicase-exonuclease AddAB subunit AddA Machinery gene
  ST4145_RS07955 (ST4145_07880) rexB 1549079..1552399 (-) 3321 WP_014727688.1 ATP-dependent nuclease subunit B Machinery gene
  ST4145_RS07960 (ST4145_07885) - 1552890..1553541 (-) 652 Protein_1515 hypothetical protein -
  ST4145_RS07965 (ST4145_07890) - 1553591..1554024 (-) 434 Protein_1516 LytTR family DNA-binding domain-containing protein -

Sequence

Protein


Download         Length: 1217 a.a.        Molecular weight: 138422.58 Da        Isoelectric Point: 4.7801

>NTDB_id=448970 ST4145_RS07950 WP_024010071.1 1545436..1549089(-) (rexA) [Streptococcus thermophilus strain 4145]
MLTKAFLSPAEIEERIAQEAASDKDRKLTPEQIEAIYSNGTNILVSASAGSGKTFVMVERILDMIGRGVGIDQLFISTFT
VKAAGELKERLEKRLTKHLGQAKTDEERAFLSDQIAKIGTADIGTMDAFTQKLVNQYGYLLGVSPTFRIMTDLAEQTLMK
NEVYADLFNDYMQGKDAQLFQKLVRNFTGHSKTSKAFRDLVYDIYSFSQATADPEKWLRQNLLKGQIEAKPEQAKNELLD
SLKDGLLADFLAFLRDHLGIAQREFAKAKYLNNVSDAIILLEGSLINDQTDMEDLLKQLLTLSGGTGLTNMTRPKDEELK
AYKEAYNKTKNEFVAQLREVDTQLTVLEVLAKHNDDILPMLELLQSFVLDFSDQYLQAKIQENTFEFSDIAHFAIRILEE
NPEVAVSYRDRYHEVMVDEYQDNSHTQERMLELLSNGHNRFMVGDIKQSIYRFRQADPQIFNDKFQLFLENPDAGKLILL
KENFRSQSEVLDATNGVFSHLMDQEIGDILYDKTHMLVAGSQKQKEPHPENETEVLIYNSDESSTSEDEEGPDQAISSGE
ISLVIKEIIKLHEQGVRFEDITLLAPNRNTYLDLMVSFEEHGIPLVPDEYKSSYLESLEVMIMLDTLRAINNPLNDYALV
ALLRSPMFNFNEDDLTRIAVQADKGQFYDKLLAAHTKSGLHPEVVMQGLDAKLTLFTETLADWRDYSKCHSIYDLIWKIY
NDRFYYDYVGGLPRAEQRQANLYALALRANAYEKTGFKGLSRFIGMIDKIIASGNDLEEVTDLVPKNAVSLMTIHKSKGL
EFKYVFVLQMNRKFIGHSKDGLSGKYIINREKGLGIKYLADLKDQINTNLPKLNVVLETLTFQENRREERRASISEEMRL
LYVAMTRAEKKLYLVGKGSKETLTQKYGTDVENNRLPVALRDQIATYQDWIMALDTAFMRKDLKFTVRFVEDEELTPEAI
GQVEVKAAVDADDLSNNRQTEEIERALTVLESVEKLNHLYAPAIDLPSVRTPSQLKTFYEPIMDTEGVDIMDKKEGVQPL
ETASTFELPDFGQKTKVTGAAVGSATHELMQRLTLSDTVTLQDLTQALSRVSASDQVKARVQLEKLLGFFDTELGKLILA
NRDKLRREAPFAMLAEDPASKEDFVVRGIIDGYLLLEDRIVLFDYKTDHFTRPSELKTRYQGQMSLYAKALSQAYQMEKV
DKYLILLGGKDLEVVEV

Nucleotide


Download         Length: 3654 bp        

>NTDB_id=448970 ST4145_RS07950 WP_024010071.1 1545436..1549089(-) (rexA) [Streptococcus thermophilus strain 4145]
ATGTTGACTAAAGCTTTTTTAAGTCCAGCAGAGATTGAGGAACGTATTGCCCAAGAAGCAGCTTCTGACAAGGATCGCAA
GTTAACACCAGAACAGATTGAAGCTATTTACAGTAATGGTACTAATATTTTGGTATCTGCCTCAGCTGGTTCAGGTAAAA
CCTTTGTCATGGTTGAGCGTATCCTTGATATGATTGGACGTGGCGTTGGTATTGATCAACTCTTTATCTCAACCTTTACG
GTAAAAGCTGCAGGTGAGTTAAAGGAGCGTCTGGAAAAGCGGCTGACAAAGCATTTAGGACAGGCTAAGACGGATGAGGA
GCGGGCATTTCTTTCAGACCAGATTGCCAAGATTGGGACGGCTGATATTGGAACCATGGATGCCTTTACCCAGAAATTGG
TCAATCAGTATGGCTATCTCCTGGGTGTGTCACCTACTTTCCGTATCATGACAGACCTTGCTGAGCAGACGCTTATGAAA
AATGAGGTTTATGCTGATCTCTTCAATGATTATATGCAAGGAAAGGATGCCCAACTTTTTCAAAAATTGGTCCGTAATTT
CACTGGACATAGCAAAACTAGCAAGGCTTTTCGTGATTTAGTTTACGATATTTACAGCTTTTCTCAGGCTACTGCAGATC
CTGAAAAATGGCTACGTCAAAATCTCTTGAAAGGACAGATCGAGGCTAAGCCAGAACAGGCTAAAAATGAGCTTTTAGAC
AGTCTTAAAGATGGATTGTTGGCTGATTTCCTAGCTTTCTTAAGAGACCATTTAGGTATAGCTCAGCGTGAATTTGCCAA
GGCCAAGTATCTGAATAATGTGTCAGATGCCATTATCCTTCTTGAGGGCTCCTTGATTAATGACCAAACTGATATGGAGG
ACCTCCTCAAACAACTATTGACTCTGTCAGGAGGTACTGGTTTGACCAATATGACCCGTCCTAAAGACGAGGAACTCAAG
GCCTACAAGGAAGCATACAACAAGACCAAAAATGAGTTTGTGGCTCAGTTGCGAGAGGTCGATACTCAGCTCACCGTTCT
GGAGGTTTTGGCCAAGCATAATGATGATATCCTACCTATGTTGGAGCTACTTCAGTCCTTTGTACTTGATTTTTCGGATC
AGTATTTACAGGCAAAGATTCAGGAAAATACCTTTGAATTCTCGGATATTGCCCACTTTGCTATCCGTATTTTGGAAGAA
AATCCAGAGGTGGCAGTCAGCTACCGGGACCGTTACCATGAAGTTATGGTGGATGAGTATCAGGACAATAGCCATACTCA
AGAACGAATGTTGGAACTTCTATCTAACGGCCATAACCGATTCATGGTGGGAGATATCAAGCAGTCCATTTATCGTTTCC
GTCAGGCAGACCCTCAGATTTTTAATGATAAGTTTCAGCTTTTCCTTGAAAATCCTGATGCAGGTAAGCTGATTCTCCTT
AAGGAGAACTTTCGTAGTCAATCTGAAGTCCTTGATGCGACAAATGGTGTTTTTAGCCACCTCATGGATCAGGAAATCGG
GGACATCCTATATGACAAGACTCATATGTTGGTAGCAGGTAGTCAGAAGCAAAAAGAGCCCCATCCTGAAAATGAAACTG
AGGTTCTGATTTATAATAGTGATGAATCTAGTACGAGTGAGGATGAAGAAGGTCCTGATCAAGCTATCAGCAGCGGTGAG
ATTTCCTTGGTTATCAAAGAAATTATCAAACTTCATGAGCAGGGTGTACGTTTTGAGGACATCACCCTCCTAGCACCGAA
CCGTAACACCTATCTGGACTTGATGGTAAGTTTCGAGGAACACGGTATTCCCTTGGTTCCTGACGAGTATAAGTCAAGCT
ACCTAGAGTCACTAGAAGTTATGATTATGTTGGACACCCTTCGTGCTATCAATAATCCTCTTAACGATTATGCTCTCGTT
GCTCTCCTTCGTTCACCTATGTTTAACTTCAACGAGGATGACCTGACTCGTATCGCAGTTCAGGCTGACAAAGGCCAATT
CTATGATAAGCTTCTTGCAGCTCATACCAAATCAGGCCTTCATCCGGAAGTTGTGATGCAAGGACTTGATGCCAAGTTGA
CTCTCTTCACAGAGACTCTGGCAGATTGGCGTGACTACAGTAAGTGTCATTCGATTTATGACCTCATTTGGAAGATTTAC
AACGACCGTTTCTATTATGATTACGTCGGAGGTCTTCCACGAGCTGAGCAACGCCAGGCCAATCTTTATGCCCTTGCCTT
GCGTGCTAATGCTTATGAAAAGACAGGATTTAAGGGGCTTTCTCGTTTTATTGGCATGATTGATAAGATTATTGCTAGCG
GTAACGACCTAGAGGAAGTGACAGATTTGGTTCCCAAAAATGCCGTTAGCCTCATGACCATTCACAAGTCCAAGGGGCTA
GAGTTCAAGTATGTCTTTGTCCTGCAGATGAATCGCAAGTTCATTGGTCACAGCAAGGATGGCCTGAGCGGTAAGTATAT
TATCAATCGTGAAAAAGGGCTTGGTATTAAGTATCTAGCTGACCTCAAAGACCAGATAAACACCAATTTGCCTAAGTTAA
ATGTTGTTCTTGAGACCTTGACCTTCCAGGAAAATCGTAGGGAAGAGCGCAGGGCAAGTATTTCAGAAGAGATGCGTCTA
CTCTATGTGGCAATGACACGTGCAGAGAAGAAACTCTACCTAGTTGGTAAGGGAAGTAAGGAAACCTTAACCCAGAAGTA
TGGCACTGATGTCGAAAATAATCGCCTACCAGTGGCTCTACGTGACCAGATTGCTACTTATCAGGATTGGATTATGGCAC
TTGATACTGCTTTTATGAGAAAGGACCTCAAGTTTACTGTTCGCTTTGTTGAGGATGAGGAGTTGACGCCAGAGGCTATT
GGACAGGTTGAAGTCAAGGCAGCAGTAGATGCCGATGATTTATCTAACAATCGTCAGACGGAGGAGATTGAGCGTGCCTT
GACTGTCTTAGAAAGTGTTGAAAAACTCAACCACCTTTATGCACCAGCGATTGACCTACCTTCTGTGCGTACCCCAAGCC
AGCTCAAGACCTTTTACGAACCAATTATGGATACAGAGGGCGTAGATATCATGGATAAGAAAGAGGGAGTGCAACCTCTT
GAGACGGCTAGCACTTTTGAGCTACCAGACTTTGGGCAAAAAACTAAGGTCACTGGAGCTGCAGTTGGTTCAGCAACCCA
TGAACTCATGCAACGCTTGACTCTTTCTGATACAGTGACTCTCCAAGATTTGACTCAGGCACTGAGTCGGGTATCGGCAT
CTGATCAAGTCAAGGCGCGTGTTCAGTTAGAAAAACTTTTAGGCTTCTTTGATACAGAGCTCGGGAAGCTTATTTTGGCC
AACCGTGATAAGTTGCGTCGTGAAGCACCTTTTGCCATGTTGGCAGAAGACCCAGCTAGTAAAGAAGACTTTGTTGTTCG
TGGAATCATTGATGGCTATCTTCTTCTTGAAGACCGTATTGTCCTCTTTGACTACAAGACCGACCACTTCACTCGTCCTA
GTGAGCTTAAGACGCGCTATCAAGGGCAAATGAGCCTCTATGCTAAAGCGCTTAGCCAAGCCTATCAAATGGAAAAGGTC
GACAAATATCTTATCCTCTTGGGTGGAAAGGACTTAGAAGTTGTAGAAGTATAA

Domains

Predicted by InterProScan.

UvrD-like helicase C-terminal domain (UvrD_C)

(478-894)

UvrD/REP helicase N-terminal domain (UvrD-helicase)

(28-464)

PD-(D/E)XK nuclease superfamily (PDDEXK_1)

(1059-1198)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  rexA Streptococcus pneumoniae R6

50.694

100

0.51