Detailed information    

insolico Bioinformatically predicted

Overview

Name   comD/blpH   Type   Regulator
Locus tag   ST4145_RS07820 Genome accession   NZ_CP065492
Coordinates   1516268..1517071 (+) Length   267 a.a.
NCBI ID   WP_228024405.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain 4145     
Function   phosphorylation of ComE; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1511268..1522071
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ST4145_RS07785 (ST4145_07715) cipB 1511854..1512093 (-) 240 WP_011681565.1 Blp family class II bacteriocin Regulator
  ST4145_RS07790 - 1512344..1512745 (-) 402 WP_011226490.1 hypothetical protein -
  ST4145_RS07795 (ST4145_07720) - 1513600..1513761 (-) 162 WP_011681568.1 hypothetical protein -
  ST4145_RS07800 (ST4145_07725) - 1513768..1513998 (-) 231 WP_011226494.1 bacteriocin class II family protein -
  ST4145_RS07805 (ST4145_07730) - 1514354..1514554 (-) 201 WP_011681569.1 hypothetical protein -
  ST4145_RS07810 (ST4145_07735) - 1514573..1514749 (-) 177 WP_011681570.1 Blp family class II bacteriocin -
  ST4145_RS07815 (ST4145_07740) - 1515000..1515737 (+) 738 WP_024010062.1 response regulator transcription factor -
  ST4145_RS07820 comD/blpH 1516268..1517071 (+) 804 WP_228024405.1 ATP-binding protein Regulator
  ST4145_RS07825 (ST4145_07750) - 1517089..1517250 (-) 162 WP_011681573.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  ST4145_RS07830 (ST4145_07755) comB 1517265..1518632 (-) 1368 WP_011681574.1 bacteriocin secretion accessory protein Regulator
  ST4145_RS07835 (ST4145_07760) - 1518648..1520802 (-) 2155 Protein_1490 peptide cleavage/export ABC transporter -

Sequence

Protein


Download         Length: 267 a.a.        Molecular weight: 30694.97 Da        Isoelectric Point: 4.8279

>NTDB_id=448968 ST4145_RS07820 WP_228024405.1 1516268..1517071(+) (comD/blpH) [Streptococcus thermophilus strain 4145]
MYLENTTHSSTLELRKLCVVISLVLFFIMIVFLDRNIREMIQGQLDFQKNLQLENLYTYNKHIEGLYNSVRSFRHDYSNL
LVTLRLGIDKDDMDIVKEAYDSVLQESDKRLNTRNFDLARLVNIQDNTLKSLLSAKVLQAEEEGIEAQISIPEPIHLIGM
ETLDFIIVTSIFLDNAIEGAIQTQNPKITISFWEDHRSQLLSISNTISEEKTETKTIFERGVSNKGRERGIGLANVTEIL
DNYINVNLETQSNNFSFTQQLTITKKA

Nucleotide


Download         Length: 804 bp        

>NTDB_id=448968 ST4145_RS07820 WP_228024405.1 1516268..1517071(+) (comD/blpH) [Streptococcus thermophilus strain 4145]
ATGTATCTTGAAAACACTACTCATTCTTCAACTTTGGAGCTTCGAAAACTCTGTGTTGTTATTTCACTTGTCCTCTTCTT
CATTATGATTGTCTTTTTAGACAGAAACATTCGTGAAATGATTCAAGGACAATTGGACTTCCAAAAAAATCTCCAGCTAG
AAAATCTCTACACCTACAATAAACATATTGAAGGTCTCTACAATTCTGTTCGTAGTTTTAGACACGATTATAGTAATCTC
TTAGTCACATTACGATTGGGGATAGATAAAGACGATATGGATATTGTCAAAGAAGCCTATGATAGTGTGCTTCAAGAATC
CGATAAACGATTAAATACAAGAAACTTTGACTTAGCTAGACTCGTTAATATTCAGGATAACACTTTGAAAAGCCTTCTGT
CCGCAAAAGTTCTACAAGCAGAAGAAGAAGGCATTGAAGCTCAGATTAGCATCCCAGAACCCATCCACTTGATTGGGATG
GAGACTCTGGACTTCATTATCGTCACTTCTATTTTTTTAGATAACGCTATTGAAGGTGCCATTCAAACTCAAAACCCTAA
AATTACTATTAGCTTTTGGGAAGATCATCGTTCACAGCTATTATCTATTAGCAATACCATAAGTGAAGAAAAAACAGAAA
CCAAAACCATATTTGAAAGAGGTGTCTCCAACAAGGGACGAGAGCGAGGCATTGGCCTTGCTAATGTCACAGAAATCTTA
GATAACTATATCAATGTAAACTTAGAAACACAGAGTAACAATTTCTCATTCACACAACAATTAACAATAACTAAAAAGGC
CTAA

Domains

Predicted by InterProScan.

GHKL domain (HATPase_c_5)

(160-263)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comD/blpH Streptococcus mutans UA159

38.189

95.131

0.363