Detailed information NTG0448850

Bioinformatically predicted

Overview

• Name: amiE
• Type: Regulator
• Locus tag: STCNRZ887_RS06435
• Genome accession: NZ_CP065491
• Coordinates: 1254494..1255579 (-)
• Length: 361 a.a.
• NCBI ID: WP_011226304.1
• Uniprot ID: Q5M3H6
• Organism: Streptococcus thermophilus strain CNRZ887
• Function: internalize XIP (predicted from homology) Competence regulation

Genomic Context

Location: 1249494..1260579

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
STCNRZ887_RS06405 (STCNRZ887_06430)	-	1249860..1250675 (-)	816	WP_011227405.1	Cof-type HAD-IIB family hydrolase	-
STCNRZ887_RS06410 (STCNRZ887_06435)	-	1250668..1251462 (-)	795	WP_059257398.1	HAD family hydrolase	-
STCNRZ887_RS06415 (STCNRZ887_06440)	-	1251645..1252022 (+)	378	WP_011226300.1	GntR family transcriptional regulator	-
STCNRZ887_RS06420 (STCNRZ887_06445)	-	1252027..1252725 (+)	699	WP_011226301.1	ABC transporter ATP-binding protein	-
STCNRZ887_RS06425 (STCNRZ887_06450)	-	1252737..1253522 (+)	786	WP_002951425.1	hypothetical protein	-
STCNRZ887_RS06430 (STCNRZ887_06455)	-	1253572..1254501 (-)	930	WP_002951426.1	ATP-binding cassette domain-containing protein	-
STCNRZ887_RS06435 (STCNRZ887_06460)	amiE	1254494..1255579 (-)	1086	WP_011226304.1	ABC transporter ATP-binding protein	Regulator
STCNRZ887_RS06440 (STCNRZ887_06465)	amiD	1255589..1256515 (-)	927	WP_002946409.1	oligopeptide ABC transporter permease OppC	Regulator
STCNRZ887_RS06445 (STCNRZ887_06470)	amiC	1256515..1258008 (-)	1494	WP_011227407.1	ABC transporter permease	Regulator
STCNRZ887_RS06450 (STCNRZ887_06475)	amiA	1258070..1260037 (-)	1968	WP_011225333.1	peptide ABC transporter substrate-binding protein	Regulator

Sequence

Protein

• Length: 361 a.a.
• Molecular weight: 39864.62 Da
• Isoelectric Point: 4.7435

>NTDB_id=448850 STCNRZ887_RS06435 WP_011226304.1 1254494..1255579(-) (amiE) [Streptococcus thermophilus strain CNRZ887]
MTENKNVILSARDIVVEFDVRDRVLTAIRGVSLDLVEGEVLALVGESGSGKSVLTKTFTGMLEENGRVASGSIDYRGKDL
TKFKSHQDWAAIRGAKIATIFQDPMTSLNPIKTIGSQIIEVIVKHQGKTAKEAKKMAIDYMDKVGIPDAEKRFNEYPFQY
SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLKEEYGFSVIFITHDLGVVASIADKVAVMYAGEIIE
YATVEEIFYEPCHPYTWSLLSSLPQLADDNGKLFSIPGTPPSLYTPVVGDAFALRSDYALQIDFEEKAPQFQVSDTHWAK
TWLLHEDAPKVDKPAVIQNLHEKILANMGFAHLGDEEEGNA

Nucleotide

• Length: 1086 bp

>NTDB_id=448850 STCNRZ887_RS06435 WP_011226304.1 1254494..1255579(-) (amiE) [Streptococcus thermophilus strain CNRZ887]
ATGACAGAAAATAAAAATGTAATATTATCGGCTCGCGATATCGTCGTGGAATTTGACGTTCGTGACCGTGTTTTGACAGC
TATTCGAGGGGTTTCTCTTGATTTAGTTGAAGGTGAAGTTTTAGCCTTGGTTGGTGAGTCTGGTTCAGGAAAATCAGTCT
TGACTAAAACTTTTACAGGGATGCTGGAAGAAAATGGTCGTGTAGCTAGCGGATCTATCGACTACCGTGGCAAAGACTTG
ACTAAATTTAAGAGTCACCAAGATTGGGCAGCTATCCGTGGAGCTAAGATTGCAACTATTTTCCAAGATCCAATGACCAG
TCTTAACCCAATTAAGACTATCGGAAGTCAAATTATTGAAGTTATTGTTAAGCACCAAGGGAAAACAGCCAAGGAAGCTA
AAAAAATGGCAATTGATTACATGGACAAGGTTGGTATTCCAGATGCTGAAAAACGTTTCAATGAATATCCTTTCCAATAC
TCTGGTGGGATGCGTCAACGTATCGTTATTGCCATTGCCTTGGCTTGTCGTCCTGATGTCCTTATCTGTGACGAACCAAC
AACTGCCCTTGATGTGACCATTCAAGCTCAAATCATTGACCTCTTGAAATCACTCAAAGAGGAGTATGGTTTCTCGGTCA
TTTTCATTACCCATGACCTTGGCGTCGTAGCAAGTATCGCGGACAAGGTTGCTGTCATGTATGCTGGCGAAATCATTGAA
TACGCAACTGTTGAGGAAATTTTCTATGAGCCTTGTCATCCATACACGTGGAGCTTGCTTTCAAGTCTGCCACAATTGGC
TGATGATAATGGAAAACTCTTCTCAATTCCAGGGACGCCACCATCACTTTATACACCAGTTGTTGGGGATGCCTTTGCCT
TGCGTTCAGATTATGCTTTGCAGATTGATTTTGAGGAAAAAGCACCACAATTCCAAGTTTCAGATACTCACTGGGCTAAG
ACCTGGCTCTTACATGAGGATGCGCCAAAAGTTGATAAACCTGCGGTTATCCAAAATCTACATGAAAAAATCCTAGCCAA
TATGGGATTTGCACATTTAGGAGATGAGGAGGAAGGCAATGCCTGA

Domains

Predicted by InterProScan.

• ABC transporter (ABC_tran) (29-187)

• Oligopeptide/dipeptide transporter, C-terminal region (oligo_HPY) (239-300)

3D structure

• AlphaFold DB: Q5M3H6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
amiE	Streptococcus thermophilus LMG 18311	100	100	1
amiE	Streptococcus thermophilus LMD-9	100	100	1
amiE	Streptococcus salivarius strain HSISS4	96.953	100	0.97
oppD	Streptococcus mutans UA159	54.441	96.676	0.526