Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   STCNRZ887_RS05880 Genome accession   NZ_CP065491
Coordinates   1138370..1140157 (-) Length   595 a.a.
NCBI ID   WP_011226197.1    Uniprot ID   Q5M3R7
Organism   Streptococcus thermophilus strain CNRZ887     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1133370..1145157
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  STCNRZ887_RS05860 (STCNRZ887_05885) - 1134333..1134974 (-) 642 Protein_1099 DNA alkylation repair protein -
  STCNRZ887_RS05865 (STCNRZ887_05890) - 1135167..1135679 (-) 513 WP_041828270.1 GNAT family N-acetyltransferase -
  STCNRZ887_RS05870 (STCNRZ887_05895) - 1135838..1136692 (+) 855 Protein_1101 transposase -
  STCNRZ887_RS05875 (STCNRZ887_05900) cls 1136731..1138281 (-) 1551 WP_179971669.1 cardiolipin synthase -
  STCNRZ887_RS05880 (STCNRZ887_05905) uvrC 1138370..1140157 (-) 1788 WP_011226197.1 excinuclease ABC subunit UvrC Machinery gene
  STCNRZ887_RS05885 (STCNRZ887_05910) - 1140217..1140912 (-) 696 WP_011226198.1 YjjG family noncanonical pyrimidine nucleotidase -
  STCNRZ887_RS05890 (STCNRZ887_05915) - 1141213..1141647 (+) 435 WP_011226199.1 biotin transporter BioY -
  STCNRZ887_RS05895 (STCNRZ887_05920) - 1141882..1142508 (-) 627 WP_002948550.1 ABC transporter permease -
  STCNRZ887_RS05900 (STCNRZ887_05925) - 1142513..1143268 (-) 756 WP_002948547.1 ABC transporter ATP-binding protein -
  STCNRZ887_RS05905 (STCNRZ887_05930) - 1143280..1144197 (-) 918 WP_002948546.1 glycine betaine ABC transporter substrate-binding protein -
  STCNRZ887_RS05910 (STCNRZ887_05935) - 1144194..1144838 (-) 645 WP_224103473.1 ABC transporter permease -

Sequence

Protein


Download         Length: 595 a.a.        Molecular weight: 68580.10 Da        Isoelectric Point: 9.5892

>NTDB_id=448844 STCNRZ887_RS05880 WP_011226197.1 1138370..1140157(-) (uvrC) [Streptococcus thermophilus strain CNRZ887]
MNDLIKHKLELLPNNPGCYLHKDKFGNIIYVGKAKNLKNRVRSYFRGSHDTKTELLVSEIADFEFIVTESNIEALLLEIN
LIQENMPKFNIRLKDGKSYPFIKITKELYPRLLITRQVKKDGGLYFGPYPDAGAANEIKKLLDRIFPFKKCKNPANKVCF
YYHIGQCKAHTICHTTEAYWQGLVEDVKNFLNGHDDKIVNQLKAKMKDMSDQMEFERAAEYRDLIEAVSTLRTKQRVIRQ
DMQDRDIFGYYVDKGWMCVQVFFVRQGKLIQRDVNMFPYYNDAEEDFLTYIGQFYLDSRHLKPKEIFIPGDIDQESVEAL
VGNEVKVFKPQRGEKKQLVNLAMKNARVSLTQKFDLLEKDIAKTQGAIENLGKLMGIPTPVRIESFDNSNIMGTSPVSAM
VVFENGKPNKKEYRKYKIKTVEGPDDYASMREVIRRRYSRVKRDGLTPPDLIIMDGGQGQVNVAKDVLRNELNLSIPVAG
LQKNDKHQTNELLFGDPLRVIDLPRQSEEFFLLHRIQDEVHRFAITFHRQVRSKNSFSSKLDGVEGLGPKRKQKLLKNFK
SMTAIQQASVEDIQALGIPEKVAQALLDKLSQDSH

Nucleotide


Download         Length: 1788 bp        

>NTDB_id=448844 STCNRZ887_RS05880 WP_011226197.1 1138370..1140157(-) (uvrC) [Streptococcus thermophilus strain CNRZ887]
ATGAACGATCTGATTAAACATAAGTTGGAATTGCTCCCAAACAACCCGGGATGTTATCTCCATAAGGACAAATTTGGCAA
TATTATCTATGTCGGTAAGGCTAAAAATCTAAAAAATCGTGTGCGTAGCTATTTTCGTGGAAGTCATGATACTAAGACGG
AGCTTCTGGTATCCGAGATTGCAGACTTTGAATTTATCGTTACCGAGTCTAATATCGAGGCCTTGCTTTTGGAAATTAAC
CTCATCCAAGAGAATATGCCTAAATTTAACATTCGCCTCAAGGATGGCAAGTCTTATCCATTTATCAAGATTACTAAGGA
ACTCTATCCAAGGCTCTTGATTACCCGCCAGGTTAAGAAGGATGGTGGTCTTTATTTTGGTCCCTACCCAGATGCTGGTG
CAGCCAATGAAATCAAGAAGCTGTTGGACCGTATTTTCCCCTTTAAGAAATGTAAAAATCCTGCCAACAAGGTCTGTTTC
TACTACCATATTGGTCAATGTAAGGCTCACACCATCTGTCACACCACCGAAGCCTATTGGCAAGGTTTGGTTGAGGATGT
CAAGAATTTCCTAAACGGTCATGATGATAAAATCGTTAACCAGCTCAAGGCCAAGATGAAGGACATGTCTGATCAGATGG
AGTTTGAGCGGGCAGCAGAATATCGAGATCTGATTGAGGCAGTGTCGACGCTCAGGACCAAACAAAGGGTTATCCGTCAA
GATATGCAGGACCGCGATATTTTCGGCTACTACGTGGACAAGGGCTGGATGTGTGTTCAGGTTTTCTTTGTCCGCCAAGG
GAAACTCATCCAGCGTGATGTCAATATGTTCCCTTACTATAATGATGCTGAGGAAGATTTTCTAACCTATATAGGTCAAT
TTTACTTGGATAGCCGTCATCTCAAGCCTAAGGAGATTTTCATTCCAGGTGACATTGATCAAGAGTCTGTCGAAGCTCTG
GTTGGAAATGAAGTCAAGGTTTTTAAACCGCAAAGAGGCGAGAAAAAGCAGTTGGTTAATCTAGCAATGAAAAATGCTCG
TGTCAGTTTGACCCAAAAATTTGATCTTCTTGAAAAAGATATAGCTAAGACCCAAGGAGCCATTGAAAATCTAGGCAAAC
TCATGGGAATTCCGACACCGGTTCGCATCGAGTCCTTCGATAACTCTAACATCATGGGAACTAGCCCTGTATCTGCCATG
GTCGTTTTTGAGAACGGCAAACCTAATAAAAAAGAGTACCGCAAATACAAGATTAAGACGGTTGAAGGGCCTGACGATTA
TGCCAGCATGCGTGAGGTCATTCGTCGCCGTTATAGTCGTGTCAAACGTGATGGTCTAACCCCACCAGACCTCATTATCA
TGGATGGTGGTCAAGGTCAGGTCAATGTCGCTAAGGACGTGCTTCGTAATGAGCTGAATCTATCTATCCCGGTTGCAGGT
CTTCAGAAAAATGACAAGCACCAAACCAATGAATTGCTCTTTGGAGATCCTTTGCGAGTCATTGATTTGCCACGTCAATC
CGAGGAGTTTTTCCTCCTTCATCGTATTCAGGATGAAGTACACCGCTTTGCCATCACCTTCCATCGACAAGTCCGTAGTA
AGAATAGTTTCAGTTCCAAACTTGATGGCGTGGAGGGGTTGGGACCTAAACGCAAACAAAAACTCCTCAAAAACTTCAAA
TCAATGACAGCTATCCAACAAGCCAGTGTCGAAGACATCCAAGCTCTTGGAATTCCTGAAAAAGTAGCTCAAGCTTTATT
AGATAAGTTGAGCCAAGATAGTCATTAA

Domains

Predicted by InterProScan.

Helix-hairpin-helix domain (HHH_5)

(540-590)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(375-525)

GIY-YIG catalytic domain (GIY-YIG)

(16-87)

UvrB/uvrC motif (UVR)

(196-229)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q5M3R7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae TIGR4

76.311

99.328

0.758
  uvrC Streptococcus pneumoniae R6

75.973

99.328

0.755
  uvrC Streptococcus pneumoniae D39

75.973

99.328

0.755