Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGH   Type   Machinery gene
Locus tag   STCNRZ1575_RS08890 Genome accession   NZ_CP065490
Coordinates   1706169..1707125 (-) Length   318 a.a.
NCBI ID   WP_011226622.1    Uniprot ID   Q5M2G5
Organism   Streptococcus thermophilus strain CNRZ1575     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1701169..1712125
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  STCNRZ1575_RS08855 (STCNRZ1575_08815) proC 1701729..1702499 (+) 771 WP_011226616.1 pyrroline-5-carboxylate reductase -
  STCNRZ1575_RS08860 (STCNRZ1575_08820) - 1702529..1703191 (-) 663 WP_023909970.1 type II CAAX endopeptidase family protein -
  STCNRZ1575_RS08865 (STCNRZ1575_08825) - 1703288..1703731 (-) 444 WP_011681680.1 hypothetical protein -
  STCNRZ1575_RS08870 - 1703805..1704143 (-) 339 WP_224103197.1 CPBP family intramembrane glutamic endopeptidase -
  STCNRZ1575_RS08875 - 1704187..1704462 (-) 276 WP_011681681.1 hypothetical protein -
  STCNRZ1575_RS08880 (STCNRZ1575_08835) - 1704474..1704671 (-) 198 WP_011681682.1 helix-turn-helix transcriptional regulator -
  STCNRZ1575_RS08885 (STCNRZ1575_08840) - 1704920..1706113 (-) 1194 WP_014608740.1 acetate kinase -
  STCNRZ1575_RS08890 (STCNRZ1575_08845) comGH 1706169..1707125 (-) 957 WP_011226622.1 class I SAM-dependent methyltransferase Machinery gene
  STCNRZ1575_RS08895 (STCNRZ1575_08850) comGG 1707170..1707487 (-) 318 WP_082309152.1 competence type IV pilus minor pilin ComGG Machinery gene
  STCNRZ1575_RS08900 (STCNRZ1575_08855) comGF 1707465..1707902 (-) 438 WP_082309153.1 competence type IV pilus minor pilin ComGF Machinery gene
  STCNRZ1575_RS08905 (STCNRZ1575_08860) comGE 1707886..1708179 (-) 294 WP_082309154.1 competence type IV pilus minor pilin ComGE Machinery gene
  STCNRZ1575_RS08910 (STCNRZ1575_08865) comGD 1708151..1708579 (-) 429 WP_253269448.1 competence type IV pilus minor pilin ComGD Machinery gene
  STCNRZ1575_RS08915 (STCNRZ1575_08870) comGC 1708539..1708865 (-) 327 WP_002946126.1 competence type IV pilus major pilin ComGC Machinery gene
  STCNRZ1575_RS08920 (STCNRZ1575_08875) comGB 1708862..1709962 (-) 1101 WP_120764773.1 competence type IV pilus assembly protein ComGB Machinery gene
  STCNRZ1575_RS08925 (STCNRZ1575_08880) comGA 1709844..1710785 (-) 942 WP_084829888.1 competence type IV pilus ATPase ComGA Machinery gene
  STCNRZ1575_RS08930 (STCNRZ1575_08885) - 1710866..1711228 (-) 363 WP_011226630.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 318 a.a.        Molecular weight: 35857.00 Da        Isoelectric Point: 4.7123

>NTDB_id=448776 STCNRZ1575_RS08890 WP_011226622.1 1706169..1707125(-) (comGH) [Streptococcus thermophilus strain CNRZ1575]
MNFEAIETAFELLLENVQTIENDLGTHAYDALIEQNSYYLGAEVANELIIKNNEKLRALNLSKEEWRRAFQFLFIKLGQL
EALQANHQFTPDAIGFIILYLLEGLTQEKQLDILEIGSGTGNLAETLLNNSQKTLNYMGMEVDDLLIDLSASIAEVVNSV
AVYIQGDAVRPHILKESNVIISDLPIGYYPNDEIASRFKVAATGEHTYAHHLLMEQSLKYLKKDGIAIFLAPTNLLTSPQ
SDLLKKWLSGYADIIAVITLPEAAFGNKHNMKSIFVLKKQTKNAPETFVYPLSDLQNPRILKDFTENFQKWKSDNSIF

Nucleotide


Download         Length: 957 bp        

>NTDB_id=448776 STCNRZ1575_RS08890 WP_011226622.1 1706169..1707125(-) (comGH) [Streptococcus thermophilus strain CNRZ1575]
ATGAATTTTGAAGCAATTGAGACAGCTTTTGAGCTGTTGTTAGAAAATGTCCAAACTATTGAAAATGATCTTGGAACCCA
TGCTTACGATGCACTTATTGAGCAAAATTCCTATTATTTGGGGGCTGAGGTTGCTAATGAGCTCATCATCAAAAACAACG
AGAAATTACGGGCGCTTAATCTAAGTAAAGAGGAGTGGCGTCGTGCTTTTCAGTTTTTGTTTATCAAACTAGGGCAATTG
GAAGCTTTACAAGCCAATCACCAATTTACACCAGATGCTATCGGATTTATCATTCTGTACTTGCTCGAAGGTTTGACCCA
GGAAAAACAATTAGATATCTTGGAGATTGGTTCGGGAACAGGAAACTTGGCTGAAACTCTTCTAAATAATAGTCAGAAAA
CCCTTAATTATATGGGGATGGAAGTTGATGATCTTCTTATCGATTTGTCAGCTAGTATTGCTGAGGTGGTGAATTCAGTA
GCGGTTTATATCCAAGGGGATGCTGTTCGACCACATATTCTCAAAGAGAGCAACGTTATTATCAGCGATTTACCTATAGG
TTACTACCCTAATGATGAGATTGCGAGTCGTTTCAAGGTGGCAGCAACTGGCGAACACACTTATGCCCATCATCTTCTTA
TGGAGCAATCGCTTAAGTATTTGAAGAAAGATGGTATTGCTATTTTTTTGGCACCAACCAATCTTTTGACAAGCCCTCAA
AGTGATCTGCTTAAGAAGTGGTTATCAGGATATGCTGATATTATTGCTGTTATTACTCTTCCAGAAGCAGCTTTTGGCAA
TAAACATAACATGAAGTCTATCTTTGTGCTAAAAAAACAAACTAAAAATGCTCCTGAGACCTTCGTTTACCCACTTAGCG
ATTTGCAAAATCCAAGGATCCTCAAGGATTTTACAGAGAATTTCCAAAAATGGAAATCAGATAATTCCATTTTCTAG

Domains

Predicted by InterProScan.

N-6 DNA Methylase (N6_Mtase)

(69-291)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q5M2G5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGH Streptococcus mutans UA159

68.889

99.057

0.682
  comGH Streptococcus mutans UA140

68.889

99.057

0.682