Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   STAVA1121_RS06780 Genome accession   NZ_CP065488
Coordinates   1272800..1273444 (-) Length   214 a.a.
NCBI ID   WP_002951384.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain AVA1121     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1267800..1278444
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  STAVA1121_RS06755 (STAVA1121_06670) - 1269897..1270895 (-) 999 WP_164178205.1 NAD(P)/FAD-dependent oxidoreductase -
  STAVA1121_RS06760 (STAVA1121_06675) trmD 1270897..1271616 (-) 720 WP_011226285.1 tRNA (guanosine(37)-N1)-methyltransferase TrmD -
  STAVA1121_RS06765 (STAVA1121_06680) rimM 1271606..1272124 (-) 519 WP_011226286.1 ribosome maturation factor RimM -
  STAVA1121_RS06780 (STAVA1121_06695) vraR 1272800..1273444 (-) 645 WP_002951384.1 response regulator transcription factor Regulator
  STAVA1121_RS06785 (STAVA1121_06700) - 1273434..1274444 (-) 1011 WP_164178207.1 sensor histidine kinase -
  STAVA1121_RS06790 (STAVA1121_06705) liaF 1274441..1275139 (-) 699 WP_011226289.1 cell wall-active antibiotics response protein LiaF -
  STAVA1121_RS06795 - 1275410..1275562 (-) 153 WP_347131144.1 ion channel -
  STAVA1121_RS06800 (STAVA1121_06715) stkP/pknB 1276199..1278070 (-) 1872 WP_347131145.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 24048.39 Da        Isoelectric Point: 4.5864

>NTDB_id=448541 STAVA1121_RS06780 WP_002951384.1 1272800..1273444(-) (vraR) [Streptococcus thermophilus strain AVA1121]
MSNKINVILVDDHEMVRLGLKSFLNLQGDVEVVGEAENGREGVDLALELRPDVVVMDLVMPELDGVQATLELLKEWPEAK
ILVLTSYLDNEKIYPVIEAGAKGYMLKTSSAAEILNSIRKVYRGEEAIETEVDNKIKYHDSHPNLHDDLTARERDILALL
AKGYDNQTIANELFISLKTVKTHVSNILGKLNVDDRTQAVVYAFRHHLVSQDDE

Nucleotide


Download         Length: 645 bp        

>NTDB_id=448541 STAVA1121_RS06780 WP_002951384.1 1272800..1273444(-) (vraR) [Streptococcus thermophilus strain AVA1121]
ATGTCGAATAAGATTAATGTAATTTTGGTAGATGACCATGAAATGGTTCGTTTAGGCCTTAAGAGTTTCTTGAATCTCCA
AGGAGATGTAGAAGTGGTTGGAGAGGCAGAAAACGGCCGTGAGGGTGTCGATCTTGCCCTGGAGCTACGACCAGATGTCG
TTGTTATGGACCTTGTTATGCCTGAGCTAGATGGTGTTCAGGCGACTTTGGAATTGCTCAAAGAATGGCCTGAAGCTAAG
ATTCTAGTTTTGACCAGCTATTTGGACAATGAAAAAATTTATCCAGTCATTGAAGCTGGCGCCAAAGGCTATATGCTTAA
AACGAGCAGTGCAGCAGAGATTCTAAATAGTATCCGTAAGGTTTACCGTGGAGAGGAAGCTATCGAAACTGAGGTAGACA
ATAAGATTAAATACCACGATAGTCACCCGAACTTACATGATGACTTGACCGCGCGCGAACGTGATATCTTAGCCCTCCTA
GCTAAAGGCTATGACAATCAAACCATTGCTAACGAACTTTTTATTTCTTTAAAAACTGTCAAGACTCATGTGTCTAATAT
CCTTGGGAAATTAAATGTTGATGACCGTACTCAGGCTGTAGTTTATGCCTTTAGACATCATCTGGTTTCACAGGATGATG
AATAA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(7-118)

Bacterial regulatory proteins, luxR family (GerE)

(149-203)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

50.485

96.262

0.486
  degU Bacillus subtilis subsp. subtilis str. 168

36.161

100

0.379