Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   STMM20_RS03725 Genome accession   NZ_CP065485
Coordinates   714075..715862 (+) Length   595 a.a.
NCBI ID   WP_116920287.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain MM20     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 709075..720862
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  STMM20_RS03695 (STMM20_03705) - 709294..710078 (+) 785 Protein_689 ABC transporter permease -
  STMM20_RS03700 - 710221..710790 (+) 570 WP_347103637.1 hypothetical protein -
  STMM20_RS03705 - 711097..711329 (-) 233 Protein_691 IS30 family transposase -
  STMM20_RS03710 (STMM20_03710) sdaAA 711513..712370 (-) 858 WP_347103690.1 L-serine ammonia-lyase, iron-sulfur-dependent, subunit alpha -
  STMM20_RS03715 (STMM20_03715) sdaAB 712371..713042 (-) 672 WP_100285098.1 L-serine ammonia-lyase, iron-sulfur-dependent subunit beta -
  STMM20_RS03720 (STMM20_03720) - 713320..714015 (+) 696 WP_347103638.1 YjjG family noncanonical pyrimidine nucleotidase -
  STMM20_RS03725 (STMM20_03725) uvrC 714075..715862 (+) 1788 WP_116920287.1 excinuclease ABC subunit UvrC Machinery gene
  STMM20_RS03730 (STMM20_03730) cls 715951..717501 (+) 1551 WP_198507002.1 cardiolipin synthase -
  STMM20_RS03735 (STMM20_03735) - 717594..718395 (-) 802 Protein_697 ISL3 family transposase -
  STMM20_RS03740 (STMM20_03740) - 718554..719066 (+) 513 WP_011681320.1 GNAT family N-acetyltransferase -
  STMM20_RS03745 (STMM20_03745) - 719427..720503 (+) 1077 WP_065973323.1 aspartate-semialdehyde dehydrogenase -

Sequence

Protein


Download         Length: 595 a.a.        Molecular weight: 68761.07 Da        Isoelectric Point: 9.3039

>NTDB_id=448217 STMM20_RS03725 WP_116920287.1 714075..715862(+) (uvrC) [Streptococcus thermophilus strain MM20]
MNDLIKHKLELLPNNPGCYLHKDKFGNIIYVGKAKNLKNRVRSYFRGSHDTKTELLVSEIADFEFIVTESNIEALLLEIN
LIQENMPKFNIRLKDGKSYPFIKITKEFYPRLLITRQVKKDGGLYFGPYPDSGAANEIKKLLDRIFPFKKCKNPANKVCF
YYHIGQCNAHTICHTTEDYWQDLVEDVKNFLNGYDDKIVNQLKAKMKDMSDQMEFERAAEYRDLIEAVSTLRTKQRVIRQ
DMQDRDIFGYYVDKGWMCVQVFFVRQGKLIQRDVNMFPYYNDAEEDFLTYMGQFYLDSRHLKPREIFIPGDIDQESVEAL
VGDEVKVFKPQRGEKKQLVNLATKNARVSLTQKFDLLEKDIAKTQGAIENLGKLMGIPTPVRIESFDNSNIMGTSPVSAM
VVFENGKPNKKEYRKYKIKTVEGPDDYASMREVIRRRYSRVKRDGLTPPDLIIMDGGQGQVNVAKDVLRNELNLSIPVAG
LQKNDKHQTNELLFGDPLRVIDLPRQSEEFFLLHRIQDEVHRFAITFHRQVRSKNSFSSKLDGVEGLGPKRKQKLLKNFK
SMTAIQQASVEDIQALGIPEKVAQALLDKLSQDSH

Nucleotide


Download         Length: 1788 bp        

>NTDB_id=448217 STMM20_RS03725 WP_116920287.1 714075..715862(+) (uvrC) [Streptococcus thermophilus strain MM20]
ATGAACGATCTGATTAAACATAAGTTGGAATTGCTCCCAAACAACCCGGGATGTTATCTCCATAAGGACAAATTTGGCAA
TATTATCTATGTCGGTAAGGCTAAAAATCTAAAAAATCGTGTGCGTAGCTATTTTCGTGGAAGTCATGATACCAAGACGG
AGCTTCTGGTATCCGAGATTGCAGACTTTGAATTTATCGTTACCGAGTCTAATATCGAGGCCTTGCTTTTGGAAATTAAC
CTCATCCAAGAGAATATGCCCAAATTCAACATCCGCCTCAAGGATGGCAAGTCTTATCCATTTATCAAGATTACTAAGGA
ATTCTATCCAAGGCTCTTGATTACCCGCCAGGTTAAGAAGGATGGTGGTCTCTATTTTGGTCCTTACCCAGACTCTGGTG
CAGCCAATGAAATCAAGAAGCTGTTGGACCGTATTTTCCCCTTTAAGAAATGTAAAAATCCTGCTAACAAGGTCTGTTTC
TATTACCATATTGGCCAATGTAATGCCCACACCATCTGTCACACCACTGAGGACTATTGGCAAGATTTGGTTGAGGATGT
CAAGAATTTTCTAAACGGTTATGATGATAAAATCGTTAACCAGCTTAAGGCCAAGATGAAGGACATGTCTGATCAGATGG
AGTTTGAGCGGGCAGCAGAATATCGAGATCTGATTGAGGCGGTATCGACACTGAGGACCAAGCAAAGGGTTATTCGTCAG
GACATGCAGGACCGTGATATCTTCGGTTACTACGTGGACAAGGGTTGGATGTGTGTTCAAGTTTTCTTTGTTCGCCAAGG
AAAACTCATCCAGCGTGATGTCAATATGTTCCCTTACTATAATGATGCTGAGGAAGATTTTCTGACCTATATGGGTCAAT
TTTACCTGGATAGTCGTCATCTTAAGCCTAGGGAAATTTTTATTCCTGGAGATATTGATCAAGAGTCTGTCGAAGCTCTG
GTCGGAGATGAAGTCAAGGTTTTTAAACCGCAAAGAGGCGAGAAAAAGCAGTTGGTTAATCTAGCAACGAAAAATGCCCG
TGTCAGCCTGACTCAAAAATTTGATCTTCTTGAAAAAGATATAGCCAAGACCCAAGGAGCCATTGAAAATCTAGGCAAAC
TCATGGGAATTCCGACACCGGTTCGCATCGAGTCCTTCGATAACTCTAACATCATGGGAACGAGCCCTGTATCTGCCATG
GTCGTTTTTGAGAACGGCAAACCTAATAAAAAAGAGTACCGCAAATACAAGATTAAGACGGTTGAAGGGCCTGACGATTA
TGCCAGCATGCGTGAGGTCATTCGTCGCCGTTATAGTCGTGTCAAACGTGATGGTCTAACCCCACCAGACCTCATTATCA
TGGATGGTGGTCAAGGTCAGGTCAATGTCGCTAAGGACGTGCTTCGTAATGAGCTGAATCTATCTATCCCGGTTGCAGGT
CTTCAGAAAAATGACAAGCACCAAACCAATGAATTGCTCTTTGGAGATCCTTTGCGAGTCATTGATTTGCCACGTCAATC
CGAGGAATTTTTCCTCCTTCACCGTATTCAGGATGAAGTACACCGCTTTGCCATCACCTTCCATCGACAAGTCCGTAGTA
AGAATAGTTTCAGTTCCAAACTTGATGGCGTGGAGGGGTTGGGACCTAAACGCAAACAAAAACTCCTCAAAAACTTCAAA
TCAATGACGGCTATCCAACAAGCCAGTGTCGAAGACATCCAAGCTCTTGGAATTCCTGAAAAAGTAGCTCAAGCTTTATT
AGATAAGTTGAGCCAAGATAGTCATTAA

Domains

Predicted by InterProScan.

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(375-525)

Helix-hairpin-helix domain (HHH_5)

(540-590)

UvrB/uvrC motif (UVR)

(196-229)

GIY-YIG catalytic domain (GIY-YIG)

(16-87)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae TIGR4

76.142

99.328

0.756
  uvrC Streptococcus pneumoniae R6

75.804

99.328

0.753
  uvrC Streptococcus pneumoniae D39

75.804

99.328

0.753