Detailed information NTG0448136

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: STMM1_RS07630
• Genome accession: NZ_CP065484
• Coordinates: 1466770..1468869 (-)
• Length: 699 a.a.
• NCBI ID: WP_071417325.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain MM1
• Function: repress competence development (at the early growth phase) (predicted from homology) Competence regulation

Genomic Context

Location: 1461770..1473869

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
STMM1_RS07595 (STMM1_07550)	pptB	1462234..1463271 (-)	1038	WP_011681529.1	ABC transporter permease	Regulator
STMM1_RS07600 (STMM1_07555)	pptA	1463268..1463999 (-)	732	WP_002951673.1	ABC transporter ATP-binding protein	Regulator
STMM1_RS07605 (STMM1_07560)	-	1464064..1464483 (+)	420	WP_011681530.1	HIT family protein	-
STMM1_RS07610 (STMM1_07565)	-	1464480..1464779 (+)	300	WP_014621895.1	hypothetical protein	-
STMM1_RS07615 (STMM1_07570)	-	1464831..1465559 (-)	729	WP_023909893.1	hypothetical protein	-
STMM1_RS07620 (STMM1_07575)	-	1465577..1466212 (-)	636	WP_022096674.1	DUF4230 domain-containing protein	-
STMM1_RS07625	-	1466231..1466356 (-)	126	WP_011681534.1	hypothetical protein	-
STMM1_RS07630 (STMM1_07580)	clpE	1466770..1468869 (-)	2100	WP_071417325.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
STMM1_RS07635 (STMM1_07585)	-	1469585..1470676 (-)	1092	WP_011681536.1	nucleotidyltransferase	-
STMM1_RS07640 (STMM1_07590)	-	1470683..1471423 (-)	741	WP_277426406.1	class I SAM-dependent methyltransferase	-
STMM1_RS07645 (STMM1_07595)	rsfS	1471748..1472101 (-)	354	WP_011227491.1	ribosome silencing factor	-
STMM1_RS07650 (STMM1_07600)	yqeK	1472125..1472715 (-)	591	WP_002951696.1	bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK	-
STMM1_RS07655 (STMM1_07605)	-	1472712..1473344 (-)	633	WP_002951698.1	nicotinate-nucleotide adenylyltransferase	-
STMM1_RS07660 (STMM1_07610)	yhbY	1473448..1473765 (-)	318	WP_002951701.1	ribosome assembly RNA-binding protein YhbY	-

Sequence

Protein

• Length: 699 a.a.
• Molecular weight: 77260.20 Da
• Isoelectric Point: 4.8280

>NTDB_id=448136 STMM1_RS07630 WP_071417325.1 1466770..1468869(-) (clpE) [Streptococcus thermophilus strain MM1]
MNNNFNNMDDLFNQLMGNMGGFRSESRRYMINGREVTPEEFAIYRQTGKLPGNQGEAVNPTQQHGPKQDGILAKLGRNLT
QEAREGKLDPVIGRNKEIQETAEILSRRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKDKEIISIDISALEAGT
QYRGSFEENIQNLVNEVKEAGNIILFFDEIHQILGAGSTGDGQGSKGLADILKPALSRGEITVIGATTQDEYRNTILKNA
ALARRFNEVKVNAPSPEDTFKILQGIRDLYEKHHNVILPDEVLKAAVDFSVQYIPQRSLPDKAIDLLDMTAAHLAAQHPV
TDVNAVEREIEEEKAKQEAAVAKEDYEAALNSKIRIEKLEKEIANHAKDRKVTATVNDVAESVERMTGIPVSQMGASDIE
RLKDMGNRLQAKVIGQDKAVEAVARSIRRNRAGFDEGNRPIGSFLFVGPTGVGKTELAKQLALDLFGTKDAIIRLDMSEY
SDRTAVSKLIGTTAGYVGYDDNSNTLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNTVIIA
TSNAGFGYEFNSTEDADKPELMDRLKPYFRPEFLNRFDAVIEFSHLDKEDLSKIVDLMLNEVNKTLSKKGIDLAVSEAAK
AYMTEEGYDEVMGARPLRRVVEQQIRDKVTDFHLDNLDAKHLEADMEDGVLVIKEKDAK

Nucleotide

• Length: 2100 bp

>NTDB_id=448136 STMM1_RS07630 WP_071417325.1 1466770..1468869(-) (clpE) [Streptococcus thermophilus strain MM1]
ATGAACAACAACTTTAATAATATGGATGATCTTTTCAATCAATTGATGGGTAACATGGGTGGTTTCCGTTCAGAAAGCCG
TCGCTACATGATTAACGGTCGTGAAGTGACACCTGAAGAATTTGCAATTTACCGTCAAACAGGTAAATTGCCTGGTAATC
AAGGTGAAGCAGTGAACCCAACACAACAACACGGACCTAAACAAGATGGTATTCTTGCTAAGCTTGGTCGTAACTTGACT
CAAGAAGCTCGTGAAGGTAAATTGGATCCTGTTATCGGACGTAACAAAGAAATCCAAGAAACTGCCGAAATTTTGTCTCG
TCGTACTAAGAATAACCCAGTCCTTGTCGGTGATGCTGGGGTTGGTAAAACAGCTGTAGTTGAAGGTTTGGCACAAGCCA
TCGTTAATGGTGATGTCCCAGCTGCTATCAAGGATAAAGAAATCATCTCAATTGATATTTCTGCACTTGAAGCTGGTACT
CAATACCGTGGTAGCTTTGAAGAAAACATTCAAAACTTGGTAAATGAAGTCAAAGAAGCTGGAAACATTATCCTCTTCTT
CGATGAAATTCATCAAATTCTTGGTGCCGGAAGCACTGGCGATGGTCAAGGTTCTAAAGGTCTGGCTGATATCTTGAAAC
CTGCTCTTTCACGTGGTGAAATAACAGTTATTGGTGCAACAACTCAAGATGAATACCGTAACACTATCTTGAAGAATGCT
GCCCTTGCTCGTCGTTTCAACGAAGTTAAGGTCAATGCTCCTTCTCCTGAAGATACCTTCAAGATTCTTCAAGGTATTCG
TGATCTTTATGAAAAACACCACAATGTTATCTTGCCAGATGAAGTCTTGAAAGCAGCGGTTGATTTTTCAGTACAATACA
TTCCACAACGTAGCTTGCCAGATAAGGCTATTGACCTTTTGGACATGACAGCAGCTCACTTGGCAGCACAACATCCAGTA
ACTGATGTCAATGCTGTTGAACGTGAAATCGAAGAAGAAAAAGCTAAACAAGAAGCTGCAGTTGCTAAAGAAGATTACGA
AGCAGCTCTAAATTCTAAGATTCGTATTGAAAAACTTGAAAAGGAAATTGCTAACCATGCAAAAGATCGCAAGGTGACTG
CGACTGTAAACGATGTGGCTGAATCCGTAGAACGTATGACTGGTATTCCAGTATCTCAAATGGGTGCATCGGATATCGAA
CGTTTGAAAGATATGGGTAACCGTTTGCAAGCTAAGGTTATCGGTCAAGATAAGGCCGTTGAAGCAGTGGCACGTTCCAT
CCGTCGTAATCGTGCAGGATTTGACGAAGGTAACCGTCCAATCGGTAGCTTCCTCTTTGTAGGACCTACTGGTGTTGGTA
AAACTGAGTTGGCTAAACAATTGGCCCTTGATTTGTTCGGTACCAAAGATGCTATCATCCGTTTGGACATGTCAGAATAC
AGCGACCGCACAGCCGTTTCTAAATTGATTGGTACAACAGCTGGTTATGTTGGTTATGATGATAATAGTAATACCTTGAC
AGAACGTGTTCGTCGTAACCCTTATTCAATCATCCTTCTTGATGAAATTGAAAAGGCAGACCCTCAAGTTATCACCCTTC
TCCTCCAAGTTTTGGATGATGGTCGTTTGACTGATGGTCAAGGTAATACTGTAAACTTCAAGAACACAGTCATTATCGCA
ACTTCAAACGCTGGCTTTGGTTACGAATTTAACTCGACAGAAGATGCTGATAAACCAGAACTCATGGATCGTTTGAAACC
TTACTTCCGTCCTGAATTCCTTAACCGTTTCGACGCAGTTATTGAGTTCTCACACTTAGATAAGGAGGACCTTTCTAAGA
TTGTCGATCTTATGTTGAATGAAGTTAACAAGACTCTTTCTAAGAAAGGCATTGACTTGGCAGTTAGCGAAGCTGCTAAA
GCCTATATGACAGAAGAAGGCTATGATGAAGTTATGGGTGCTCGTCCACTCCGTCGTGTGGTTGAACAACAAATCCGTGA
CAAAGTCACAGACTTCCACTTGGATAACCTTGATGCAAAACACCTAGAAGCTGATATGGAAGATGGTGTCTTAGTTATCA
AAGAAAAAGATGCTAAATAA

Domains

Predicted by InterProScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (606-676)

• AAA lid domain (AAA_lid_9) (255-349)

• AAA domain (Cdc48 subfamily) (AAA_2) (439-599)

• ATPase family associated with various cellular activities (AAA) (AAA) (114-246)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus mutans UA159	46.781	100	0.468
clpC	Lactococcus lactis subsp. cremoris KW2	49.219	91.559	0.451
clpE	Streptococcus pneumoniae Rx1	48.657	90.558	0.441
clpE	Streptococcus pneumoniae R6	48.657	90.558	0.441
clpE	Streptococcus pneumoniae D39	48.657	90.558	0.441
clpE	Streptococcus pneumoniae TIGR4	48.657	90.558	0.441
clpC	Bacillus subtilis subsp. subtilis str. 168	45.975	92.418	0.425
clpC	Streptococcus thermophilus LMD-9	43.103	91.273	0.393
clpC	Streptococcus thermophilus LMG 18311	42.947	91.273	0.392
clpC	Streptococcus pneumoniae TIGR4	43.248	88.984	0.385
clpC	Streptococcus pneumoniae Rx1	43.248	88.984	0.385
clpC	Streptococcus pneumoniae D39	43.248	88.984	0.385
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	43.598	88.269	0.385
clpC	Streptococcus mutans UA159	42.995	88.841	0.382