Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   STCNRZ760_RS06285 Genome accession   NZ_CP065482
Coordinates   1196326..1198113 (-) Length   595 a.a.
NCBI ID   WP_176243233.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain CNRZ760     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1191326..1203113
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  STCNRZ760_RS06265 (STCNRZ760_06220) - 1191685..1192761 (-) 1077 WP_065973323.1 aspartate-semialdehyde dehydrogenase -
  STCNRZ760_RS06270 (STCNRZ760_06225) - 1193122..1193634 (-) 513 WP_022096706.1 GNAT family N-acetyltransferase -
  STCNRZ760_RS06275 (STCNRZ760_06230) - 1193793..1194648 (+) 856 Protein_1182 transposase -
  STCNRZ760_RS06280 (STCNRZ760_06235) cls 1194687..1196237 (-) 1551 WP_173940707.1 cardiolipin synthase -
  STCNRZ760_RS06285 (STCNRZ760_06240) uvrC 1196326..1198113 (-) 1788 WP_176243233.1 excinuclease ABC subunit UvrC Machinery gene
  STCNRZ760_RS06290 (STCNRZ760_06245) - 1198173..1198868 (-) 696 WP_176243232.1 YjjG family noncanonical pyrimidine nucleotidase -
  STCNRZ760_RS06295 (STCNRZ760_06250) - 1199060..1199602 (+) 543 WP_002948552.1 biotin transporter BioY -
  STCNRZ760_RS06300 (STCNRZ760_06255) - 1199837..1200463 (-) 627 WP_002948550.1 ABC transporter permease -
  STCNRZ760_RS06305 (STCNRZ760_06260) - 1200468..1201223 (-) 756 WP_002948547.1 ABC transporter ATP-binding protein -
  STCNRZ760_RS06310 (STCNRZ760_06265) - 1201235..1202152 (-) 918 WP_002948546.1 glycine betaine ABC transporter substrate-binding protein -
  STCNRZ760_RS06315 (STCNRZ760_06270) - 1202149..1202793 (-) 645 WP_224103473.1 ABC transporter permease -

Sequence

Protein


Download         Length: 595 a.a.        Molecular weight: 68626.12 Da        Isoelectric Point: 9.5159

>NTDB_id=447914 STCNRZ760_RS06285 WP_176243233.1 1196326..1198113(-) (uvrC) [Streptococcus thermophilus strain CNRZ760]
MNDLIKHKLELLPNSPGCYLHKDKFGNIIYVGKAKNLKNRVRSYFRGSHDTKTELLVSEIADFEFIVTESNIEALLLEIN
LIQENMPKFNIRLKDGKSYPFIKITKELYPRLLITRQVKKDGGLYFGPYPDSGAANEIKKLLDRIFPFKKCKNPANKVCF
YYHIGQCKAHTICHTTEAYWQGLVEDVKNFLNGYDDKIVNQLKVKMKDMSDQMEFERAAEYRDLIEAVSTLRTKQRVIRQ
DMQDRDIFGYYVDKGWMCVQVFFVRQGKLIQRDVNMFPYYNDAEEDFLTYMGQFYLDSRHLKPKEIFIPGDIDQESVEAL
VGDEVKVFKPQRGEKKQLVNLATKNARVSLTQKFDLLEKDIAKTQGAIENLGKLMGIPTPVRIESFDNSNIMGTSPVSAM
VVFENGKPNKKEYRKYKIKTVEGPDDYASMREVIRRRYSRVKRDGLTPPDLIIMDGGQGQVNIAKDVLRNELNLSIPVAG
LQKNDKHQTNELLFGDPLRVIDLPRQSEEFFLLHRIQDEVHRFAITFHRQVRSKNSFSSKLDGVEGLGPKRKQKLLKNFK
SMTAIQQASVEDIQALGIPEKVAQALLDKLSQDSH

Nucleotide


Download         Length: 1788 bp        

>NTDB_id=447914 STCNRZ760_RS06285 WP_176243233.1 1196326..1198113(-) (uvrC) [Streptococcus thermophilus strain CNRZ760]
ATGAACGATCTGATTAAACATAAGTTGGAATTGCTCCCAAACAGCCCGGGATGTTATCTCCATAAGGACAAATTTGGCAA
TATTATCTATGTCGGTAAGGCTAAAAATCTAAAAAATCGTGTGCGTAGCTATTTTCGTGGAAGTCATGATACCAAGACGG
AGCTTCTGGTATCCGAGATTGCAGACTTTGAATTTATCGTTACCGAGTCTAATATCGAGGCCTTGCTTTTGGAAATTAAC
CTCATCCAAGAGAATATGCCCAAATTCAACATCCGCCTCAAGGATGGCAAGTCTTATCCATTTATCAAGATTACTAAGGA
ACTCTATCCAAGGCTCTTGATTACCCGCCAGGTTAAGAAGGATGGTGGTCTCTATTTTGGTCCTTACCCAGACTCTGGTG
CAGCCAATGAAATCAAGAAGCTATTGGACCGTATTTTCCCCTTTAAGAAATGTAAAAATCCTGCTAACAAGGTCTGTTTC
TATTACCATATTGGCCAATGTAAGGCTCACACCATCTGTCACACCACCGAAGCCTATTGGCAAGGTTTGGTTGAGGATGT
CAAGAATTTTCTAAACGGTTATGATGATAAAATCGTTAACCAGCTTAAGGTCAAGATGAAGGACATGTCTGATCAGATGG
AGTTTGAGCGGGCAGCGGAGTATCGCGATTTGATTGAGGCGGTATCGACACTGAGGACCAAGCAAAGGGTTATCCGTCAA
GATATGCAGGACCGCGATATTTTCGGCTACTACGTGGACAAGGGCTGGATGTGTGTTCAGGTTTTCTTTGTCCGCCAAGG
GAAACTCATCCAGCGTGATGTCAATATGTTCCCTTACTATAATGATGCTGAGGAAGATTTTCTAACCTATATGGGTCAAT
TTTACTTGGATAGCCGTCATCTCAAGCCTAAGGAGATTTTCATTCCAGGGGACATTGATCAAGAGTCTGTCGAAGCTCTA
GTCGGAGATGAAGTCAAGGTTTTTAAACCGCAAAGAGGCGAGAAAAAGCAGTTGGTTAATCTGGCAACGAAAAATGCTCG
TGTCAGTTTGACCCAAAAATTTGATCTTCTTGAAAAAGATATAGCCAAGACCCAAGGAGCCATTGAAAATCTAGGCAAAC
TCATGGGAATTCCGACACCGGTTCGCATCGAGTCCTTCGATAACTCTAACATCATGGGAACGAGCCCTGTATCTGCCATG
GTCGTTTTTGAGAACGGCAAACCTAATAAAAAAGAGTACCGCAAATACAAGATTAAGACGGTTGAAGGGCCTGACGATTA
TGCCAGCATGCGTGAGGTCATTCGTCGCCGTTATAGTCGTGTCAAACGTGATGGTCTAACCCCACCAGACCTCATTATCA
TGGATGGTGGTCAAGGTCAGGTCAATATCGCTAAGGACGTGCTTCGTAATGAGCTGAATCTATCTATCCCGGTTGCAGGT
CTTCAGAAAAATGACAAGCACCAAACCAATGAATTGCTCTTTGGAGATCCTTTGCGAGTCATTGATTTGCCACGTCAATC
CGAGGAATTTTTCCTCCTTCACCGTATTCAGGATGAAGTACACCGCTTTGCCATCACCTTCCATCGACAAGTCCGTAGTA
AGAATAGTTTCAGTTCCAAACTTGATGGCGTGGAGGGGTTGGGACCTAAACGCAAACAAAAACTCCTCAAAAACTTCAAA
TCAATGACAGCTATCCAACAAGCCAGTGTCGAAGACATCCAAGCTCTTGGAATTCCTGAAAAAGTAGCTCAAGCTTTATT
AGATAAGTTGAGCCAAGATAGTCATTAA

Domains

Predicted by InterProScan.

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(375-525)

GIY-YIG catalytic domain (GIY-YIG)

(17-87)

Helix-hairpin-helix domain (HHH_5)

(540-590)

UvrB/uvrC motif (UVR)

(197-229)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae TIGR4

76.65

99.328

0.761
  uvrC Streptococcus pneumoniae R6

76.311

99.328

0.758
  uvrC Streptococcus pneumoniae D39

76.311

99.328

0.758