Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   ST90729_RS06275 Genome accession   NZ_CP065480
Coordinates   1214396..1216183 (-) Length   595 a.a.
NCBI ID   WP_176243233.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain 90729     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1209396..1221183
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ST90729_RS06255 (ST90729_06255) - 1209757..1210833 (-) 1077 WP_011227331.1 aspartate-semialdehyde dehydrogenase -
  ST90729_RS06260 (ST90729_06260) - 1211194..1211706 (-) 513 WP_002951148.1 GNAT family N-acetyltransferase -
  ST90729_RS06265 (ST90729_06265) - 1211983..1212665 (+) 683 Protein_1179 ISL3 family transposase -
  ST90729_RS06270 (ST90729_06270) cls 1212757..1214307 (-) 1551 WP_187145726.1 cardiolipin synthase -
  ST90729_RS06275 (ST90729_06275) uvrC 1214396..1216183 (-) 1788 WP_176243233.1 excinuclease ABC subunit UvrC Machinery gene
  ST90729_RS06280 (ST90729_06280) - 1216243..1216947 (-) 705 Protein_1182 YjjG family noncanonical pyrimidine nucleotidase -
  ST90729_RS06285 (ST90729_06285) sdaAB 1217225..1217896 (+) 672 WP_041827062.1 L-serine ammonia-lyase, iron-sulfur-dependent subunit beta -
  ST90729_RS06290 (ST90729_06290) sdaAA 1217909..1218778 (+) 870 WP_347116346.1 L-serine ammonia-lyase, iron-sulfur-dependent, subunit alpha -
  ST90729_RS06295 - 1218962..1219194 (+) 233 Protein_1185 IS30 family transposase -
  ST90729_RS06300 (ST90729_06295) - 1220213..1221004 (-) 792 Protein_1186 ABC transporter permease -

Sequence

Protein


Download         Length: 595 a.a.        Molecular weight: 68626.12 Da        Isoelectric Point: 9.5159

>NTDB_id=447704 ST90729_RS06275 WP_176243233.1 1214396..1216183(-) (uvrC) [Streptococcus thermophilus strain 90729]
MNDLIKHKLELLPNSPGCYLHKDKFGNIIYVGKAKNLKNRVRSYFRGSHDTKTELLVSEIADFEFIVTESNIEALLLEIN
LIQENMPKFNIRLKDGKSYPFIKITKELYPRLLITRQVKKDGGLYFGPYPDSGAANEIKKLLDRIFPFKKCKNPANKVCF
YYHIGQCKAHTICHTTEAYWQGLVEDVKNFLNGYDDKIVNQLKVKMKDMSDQMEFERAAEYRDLIEAVSTLRTKQRVIRQ
DMQDRDIFGYYVDKGWMCVQVFFVRQGKLIQRDVNMFPYYNDAEEDFLTYMGQFYLDSRHLKPKEIFIPGDIDQESVEAL
VGDEVKVFKPQRGEKKQLVNLATKNARVSLTQKFDLLEKDIAKTQGAIENLGKLMGIPTPVRIESFDNSNIMGTSPVSAM
VVFENGKPNKKEYRKYKIKTVEGPDDYASMREVIRRRYSRVKRDGLTPPDLIIMDGGQGQVNIAKDVLRNELNLSIPVAG
LQKNDKHQTNELLFGDPLRVIDLPRQSEEFFLLHRIQDEVHRFAITFHRQVRSKNSFSSKLDGVEGLGPKRKQKLLKNFK
SMTAIQQASVEDIQALGIPEKVAQALLDKLSQDSH

Nucleotide


Download         Length: 1788 bp        

>NTDB_id=447704 ST90729_RS06275 WP_176243233.1 1214396..1216183(-) (uvrC) [Streptococcus thermophilus strain 90729]
ATGAACGATCTGATTAAACATAAGTTGGAATTGCTCCCAAACAGCCCGGGATGTTATCTCCATAAGGACAAATTTGGCAA
TATTATCTATGTCGGTAAGGCTAAAAATCTAAAAAATCGTGTGCGTAGCTATTTTCGTGGAAGTCATGATACCAAGACGG
AGCTTCTGGTATCCGAGATTGCAGACTTTGAATTTATCGTTACCGAGTCTAATATCGAGGCCTTGCTTTTGGAAATTAAC
CTCATCCAAGAGAATATGCCCAAATTCAACATCCGCCTCAAGGATGGCAAGTCTTATCCATTTATCAAGATTACTAAGGA
ACTCTATCCAAGGCTCTTGATTACCCGCCAGGTTAAGAAGGATGGTGGTCTCTATTTTGGTCCTTACCCAGACTCTGGTG
CAGCCAATGAAATCAAGAAGCTATTGGACCGTATTTTCCCCTTTAAGAAATGTAAAAATCCTGCTAACAAGGTCTGTTTC
TATTACCATATTGGCCAATGTAAGGCTCACACCATCTGTCACACCACCGAAGCCTATTGGCAAGGTTTGGTTGAGGATGT
CAAGAATTTTCTAAACGGTTATGATGATAAAATCGTTAACCAGCTTAAGGTCAAGATGAAGGACATGTCTGATCAGATGG
AGTTTGAGCGGGCAGCGGAGTATCGCGATTTGATTGAGGCGGTATCGACACTGAGGACCAAGCAAAGGGTTATCCGTCAA
GATATGCAGGACCGCGATATTTTCGGCTACTACGTGGACAAGGGCTGGATGTGTGTTCAGGTTTTCTTTGTCCGCCAAGG
GAAACTCATCCAGCGTGATGTCAATATGTTCCCTTACTATAATGATGCTGAGGAAGATTTTCTAACCTATATGGGTCAAT
TTTACTTGGATAGCCGTCATCTCAAGCCTAAGGAGATTTTCATTCCAGGGGACATTGATCAAGAGTCTGTCGAAGCTCTA
GTCGGAGATGAAGTCAAGGTTTTTAAACCGCAAAGAGGCGAGAAAAAGCAGTTGGTTAATCTGGCAACGAAAAATGCTCG
TGTCAGTTTGACCCAAAAATTTGATCTTCTTGAAAAAGATATAGCCAAGACCCAAGGAGCCATTGAAAATCTAGGCAAAC
TCATGGGAATTCCGACACCGGTTCGCATCGAGTCCTTCGATAACTCTAACATCATGGGAACGAGCCCTGTATCTGCCATG
GTCGTTTTTGAGAACGGCAAACCTAATAAAAAAGAGTACCGCAAATACAAGATTAAGACGGTTGAAGGGCCTGACGATTA
TGCCAGCATGCGTGAGGTCATTCGTCGCCGTTATAGTCGTGTCAAACGTGATGGTCTAACCCCACCAGACCTCATTATCA
TGGATGGTGGTCAAGGTCAGGTCAATATCGCTAAGGACGTGCTTCGTAATGAGCTGAATCTATCTATCCCGGTTGCAGGT
CTTCAGAAAAATGACAAGCACCAAACCAATGAATTGCTCTTTGGAGATCCTTTGCGAGTCATTGATTTGCCACGTCAATC
CGAGGAGTTTTTCCTCCTTCACCGTATTCAGGATGAAGTACACCGCTTTGCCATCACCTTCCATCGACAAGTCCGTAGTA
AGAATAGTTTCAGTTCCAAACTTGATGGCGTGGAGGGGTTGGGACCTAAACGCAAACAAAAACTCCTCAAAAACTTCAAA
TCAATGACAGCTATCCAACAAGCCAGTGTCGAAGACATCCAAGCTCTTGGAATTCCTGAAAAAGTAGCTCAAGCTTTATT
AGATAAGTTGAGCCAAGATAGTCATTAA

Domains

Predicted by InterProScan.

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(375-525)

GIY-YIG catalytic domain (GIY-YIG)

(17-87)

Helix-hairpin-helix domain (HHH_5)

(540-590)

UvrB/uvrC motif (UVR)

(197-229)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae TIGR4

76.65

99.328

0.761
  uvrC Streptococcus pneumoniae R6

76.311

99.328

0.758
  uvrC Streptococcus pneumoniae D39

76.311

99.328

0.758