Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   ST90728_RS06350 Genome accession   NZ_CP065479
Coordinates   1222199..1223986 (-) Length   595 a.a.
NCBI ID   WP_022097069.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain 90728     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1217199..1228986
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ST90728_RS06330 (ST90728_06320) - 1217558..1218634 (-) 1077 WP_022096708.1 aspartate-semialdehyde dehydrogenase -
  ST90728_RS06335 (ST90728_06325) - 1218995..1219507 (-) 513 WP_347113746.1 N-acetyltransferase family protein -
  ST90728_RS06340 (ST90728_06330) - 1219666..1220468 (+) 803 Protein_1195 transposase -
  ST90728_RS06345 (ST90728_06335) cls 1220560..1222110 (-) 1551 WP_347114642.1 cardiolipin synthase -
  ST90728_RS06350 (ST90728_06340) uvrC 1222199..1223986 (-) 1788 WP_022097069.1 excinuclease ABC subunit UvrC Machinery gene
  ST90728_RS06355 (ST90728_06345) - 1224046..1224741 (-) 696 WP_022097070.1 YjjG family noncanonical pyrimidine nucleotidase -
  ST90728_RS06360 (ST90728_06350) - 1225068..1225502 (+) 435 WP_347113749.1 biotin transporter BioY -
  ST90728_RS06365 (ST90728_06355) - 1225737..1226363 (-) 627 WP_002948550.1 ABC transporter permease -
  ST90728_RS06370 (ST90728_06360) - 1226368..1227123 (-) 756 WP_002948547.1 ABC transporter ATP-binding protein -
  ST90728_RS06375 (ST90728_06365) - 1227135..1228052 (-) 918 WP_002948546.1 glycine betaine ABC transporter substrate-binding protein -
  ST90728_RS06380 (ST90728_06370) - 1228049..1228693 (-) 645 WP_224103473.1 ABC transporter permease -

Sequence

Protein


Download         Length: 595 a.a.        Molecular weight: 68523.97 Da        Isoelectric Point: 9.5291

>NTDB_id=447594 ST90728_RS06350 WP_022097069.1 1222199..1223986(-) (uvrC) [Streptococcus thermophilus strain 90728]
MNDLIKHKLELLPNSPGCYLHKDKFGNIIYVGKAKNLKNRVRSYFRGSHDTKTELLVSEIADFEFIVTESNIEALLLEIN
LIQENMPKFNIRLKDGKSYPFIKITKELYPRLLITRQVKKDGGLYFGPYPDAGAANEIKKLLDRIFPFKKCKNPANKVCF
YYHIGQCKAHTICHTTEAYWQGLVEDVKNFLNGHDDKIVNQLKAKMKDMSDQMEFERAAEYRDLIEAVSTLRTKQRVIRQ
DMQDRDIFGYYVDKGWMCVQVFFVRQGKLIQRDVNIFPYYNDAEEDFLTYMGQFYLDSRHLKPKEIFIPGDIDQESVEAL
VGDEVKVFKPQRGEKKQLVNLATKNARVSLTQKFDLLEKDIAKTQGAIENLGKLMGIPTPVRIESFDNSNIMGTSPVSAM
VVFENGKPNKKEYRKYKIKTVEGPDDYASMREVIRRRYSRVKRDGLTPPDLIIMDGGQGQVNVAKDVLRNELNLSIPVAG
LQKNDKHQTNELLFGDPLRVIDLPRQSEEFFLLHRIQDEVHRFAITFHRQVRSKNSFSSKLDGVEGLGPKRKQKLLKNFK
SMTAIQQASVEDIQALGIPEKVAQALLDKLSQDSH

Nucleotide


Download         Length: 1788 bp        

>NTDB_id=447594 ST90728_RS06350 WP_022097069.1 1222199..1223986(-) (uvrC) [Streptococcus thermophilus strain 90728]
ATGAACGATCTGATTAAACATAAGTTGGAACTGCTCCCAAACAGCCCGGGATGTTATCTCCATAAGGACAAATTCGGCAA
TATTATTTATGTCGGTAAGGCTAAAAATCTAAAAAATCGTGTGCGTAGCTATTTTCGTGGAAGCCATGATACCAAGACGG
AGCTTTTGGTATCTGAGATTGCAGACTTTGAATTTATCGTAACCGAGTCTAATATCGAGGCCTTGCTTTTGGAAATTAAC
CTCATCCAAGAGAATATGCCTAAATTTAACATTCGTCTCAAGGATGGCAAGTCTTATCCATTTATCAAGATTACTAAGGA
ACTCTATCCAAGGCTCTTGATTACCCGCCAGGTTAAGAAGGATGGTGGTCTTTATTTTGGTCCCTACCCAGATGCTGGTG
CAGCCAATGAAATCAAGAAGCTGTTGGACCGTATTTTCCCCTTTAAGAAATGTAAAAATCCTGCCAACAAGGTCTGTTTC
TATTACCATATTGGTCAATGTAAGGCTCACACCATCTGTCACACCACCGAAGCCTATTGGCAAGGTTTGGTTGAGGATGT
CAAGAATTTCCTAAACGGTCATGATGATAAAATCGTTAACCAGCTCAAGGCCAAGATGAAGGACATGTCTGATCAGATGG
AGTTTGAGCGGGCAGCAGAATATCGAGATCTGATTGAGGCGGTATCGACACTGAGGACCAAGCAAAGGGTTATCCGTCAG
GACATGCAGGACCGTGATATCTTCGGTTACTACGTGGACAAGGGTTGGATGTGTGTTCAAGTTTTCTTTGTTCGCCAAGG
AAAACTCATCCAGCGTGATGTCAATATATTCCCTTACTATAATGATGCTGAGGAAGATTTTCTAACCTATATGGGTCAAT
TTTACTTGGATAGCCGTCATCTCAAGCCTAAGGAGATTTTCATTCCAGGAGATATTGATCAAGAGTCTGTCGAAGCTCTG
GTCGGAGATGAAGTCAAGGTTTTTAAACCGCAAAGAGGCGAGAAAAAGCAGTTGGTTAATCTGGCAACGAAAAATGCTCG
TGTCAGTTTGACCCAAAAATTTGATCTTCTTGAAAAAGATATAGCCAAGACCCAAGGAGCCATTGAAAATCTAGGCAAAC
TCATGGGAATTCCGACACCGGTTCGCATCGAGTCCTTCGATAACTCTAACATCATGGGAACGAGCCCTGTATCTGCCATG
GTCGTTTTTGAGAACGGCAAACCTAATAAAAAAGAGTACCGCAAATACAAGATTAAGACGGTTGAAGGGCCTGACGATTA
TGCCAGCATGCGTGAGGTCATTCGTCGCCGTTATAGTCGTGTCAAACGTGATGGTCTAACCCCACCAGACCTCATTATCA
TGGATGGTGGTCAAGGTCAGGTCAATGTCGCTAAGGACGTGCTTCGTAATGAGCTGAATCTATCTATCCCGGTTGCAGGT
CTTCAGAAAAATGACAAGCACCAAACCAATGAATTGCTCTTTGGAGATCCTTTGCGAGTCATTGATTTGCCACGTCAATC
CGAGGAATTTTTCCTCCTTCACCGTATTCAGGATGAAGTACACCGCTTTGCCATCACCTTCCATCGACAAGTCCGTAGTA
AGAATAGTTTCAGTTCCAAACTTGATGGCGTGGAGGGGTTGGGACCTAAACGCAAACAAAAACTCCTCAAAAACTTCAAA
TCAATGACAGCTATCCAACAAGCCAGTGTCGAAGACATCCAAGCTCTTGGAATTCCTGAAAAAGTAGCTCAAGCTTTATT
AGATAAGTTGAGCCAAGATAGTCATTAA

Domains

Predicted by InterProScan.

Helix-hairpin-helix domain (HHH_5)

(540-590)

GIY-YIG catalytic domain (GIY-YIG)

(17-87)

UvrB/uvrC motif (UVR)

(196-229)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(375-525)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae TIGR4

76.481

99.328

0.76
  uvrC Streptococcus pneumoniae R6

76.142

99.328

0.756
  uvrC Streptococcus pneumoniae D39

76.142

99.328

0.756