Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   GE022_RS07825 Genome accession   NZ_CP053790
Coordinates   1596326..1597651 (-) Length   441 a.a.
NCBI ID   WP_164405057.1    Uniprot ID   -
Organism   Streptococcus canis strain HL_77_2     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1591326..1602651
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GE022_RS07810 (GE022_007800) - 1594055..1595009 (+) 955 Protein_1495 IS30 family transposase -
  GE022_RS07815 (GE022_007805) hpf 1595061..1595609 (-) 549 WP_093999503.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  GE022_RS07820 (GE022_007810) - 1595689..1596354 (-) 666 WP_164405056.1 ComF family protein -
  GE022_RS07825 (GE022_007815) comFA/cflA 1596326..1597651 (-) 1326 WP_164405057.1 DEAD/DEAH box helicase Machinery gene
  GE022_RS07830 (GE022_007820) - 1597707..1598339 (+) 633 WP_164405058.1 YigZ family protein -
  GE022_RS07835 (GE022_007825) cysK 1598457..1599392 (+) 936 WP_003044700.1 cysteine synthase A -
  GE022_RS07840 (GE022_007830) - 1599559..1599918 (-) 360 WP_003044703.1 S1 RNA-binding domain-containing protein -
  GE022_RS07845 (GE022_007835) - 1599918..1601318 (-) 1401 WP_164405059.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  GE022_RS07850 (GE022_007840) - 1601355..1601996 (-) 642 WP_003044709.1 response regulator transcription factor -

Sequence

Protein


Download         Length: 441 a.a.        Molecular weight: 49713.83 Da        Isoelectric Point: 9.7993

>NTDB_id=447227 GE022_RS07825 WP_164405057.1 1596326..1597651(-) (comFA/cflA) [Streptococcus canis strain HL_77_2]
MEGIENYYGRLFLENQLPEEGKHLAKPLESIVITKGKVTCQRCRYHISEEERLPSGAYYCRFCLVFGRNQSDKSLYYMSP
KPFPQGSCLKWKGQLTPHQKKISQQLVRNVQAKKPTLVHAVTGAGKTEMIYAAIARVIEAGGWVCLASPRVDVCIEVAKR
LSQAFSCQVCLMHAGSSPYQRSPIIVATTHQLLAFYKAFDLLIIDEVDAFPFVTNVQLNHAANQASKTDAARILLTATST
TTLEKQVKRGEVEKLTLARRFHNHPLVIPQFIRSFAILNNIHCHKIPEIVIKYLREQRQTGYPLLIFLPVITTAEIVTNL
LKKAFPKEKIACVSSQAEEREKDITAFRQGEKTILVTTTILERGVTFPGVDVFVLAAHHRVFTPQSLVQISGRVGRSLER
PTGNLYFFHDGISRAMLKARKEIKEMNQKGYPDDMSTVPTT

Nucleotide


Download         Length: 1326 bp        

>NTDB_id=447227 GE022_RS07825 WP_164405057.1 1596326..1597651(-) (comFA/cflA) [Streptococcus canis strain HL_77_2]
ATGGAAGGTATTGAAAATTATTACGGTCGTTTATTTTTAGAAAATCAATTGCCAGAAGAAGGAAAGCATCTTGCAAAACC
TTTAGAAAGTATAGTAATTACAAAAGGTAAGGTTACTTGCCAACGATGCCGTTACCACATTAGTGAGGAAGAAAGATTGC
CTAGTGGCGCTTATTATTGCCGCTTCTGTCTTGTCTTTGGCCGCAATCAATCTGATAAATCGCTTTACTATATGTCCCCT
AAGCCATTCCCTCAAGGAAGCTGTCTTAAATGGAAAGGACAATTAACACCTCATCAAAAAAAGATTTCCCAACAGTTGGT
AAGAAATGTACAGGCCAAAAAGCCTACCTTGGTTCATGCTGTAACAGGAGCTGGTAAAACAGAAATGATTTATGCAGCTA
TTGCAAGAGTTATTGAAGCAGGTGGCTGGGTATGTTTAGCTAGCCCGCGAGTAGATGTTTGTATCGAAGTGGCCAAACGG
TTATCTCAAGCCTTTTCGTGTCAAGTCTGTTTAATGCATGCTGGATCCTCTCCTTACCAGAGAAGTCCTATTATTGTAGC
AACAACACATCAGTTACTCGCTTTTTACAAGGCTTTTGACCTTTTGATTATTGATGAAGTTGATGCTTTTCCATTTGTGA
CAAACGTTCAACTGAATCACGCTGCAAATCAAGCCTCTAAAACAGATGCTGCTAGGATTTTATTAACAGCAACATCAACG
ACAACCTTAGAAAAACAAGTCAAAAGAGGAGAAGTAGAAAAGCTAACATTAGCTAGGCGCTTTCATAATCATCCCTTAGT
TATTCCACAGTTTATCAGAAGTTTTGCTATCTTGAACAATATACACTGCCATAAGATTCCTGAAATAGTCATCAAATACC
TTCGAGAGCAGCGGCAGACAGGTTATCCCCTGTTAATATTTCTTCCTGTTATTACAACAGCAGAAATAGTCACCAATTTG
TTAAAAAAAGCTTTTCCAAAAGAAAAGATAGCTTGTGTTTCAAGTCAAGCAGAAGAGAGGGAAAAAGATATTACTGCCTT
TCGCCAGGGTGAAAAAACTATTTTAGTCACGACAACAATCTTGGAAAGGGGGGTTACCTTTCCTGGTGTTGATGTCTTTG
TACTAGCAGCCCACCATCGAGTTTTCACCCCACAAAGTCTTGTTCAAATCTCGGGCCGTGTGGGAAGATCTCTGGAGAGA
CCGACAGGGAACTTATACTTTTTTCATGATGGTATCAGTAGAGCAATGTTGAAGGCTCGAAAAGAAATCAAAGAAATGAA
TCAGAAAGGTTACCCAGATGACATGTCTACTGTGCCAACAACCTAG

Domains

Predicted by InterproScan.

Helicase conserved C-terminal domain (Helicase_C)

(287-396)

DEAD/DEAH box helicase (DEAD)

(98-245)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus pneumoniae Rx1

55.294

96.372

0.533
  comFA/cflA Streptococcus pneumoniae D39

55.294

96.372

0.533
  comFA/cflA Streptococcus pneumoniae R6

55.294

96.372

0.533
  comFA/cflA Streptococcus pneumoniae TIGR4

55.294

96.372

0.533
  comFA/cflA Streptococcus mitis NCTC 12261

54.118

96.372

0.522
  comFA/cflA Streptococcus mitis SK321

53.63

96.825

0.519
  comFA Lactococcus lactis subsp. cremoris KW2

45.476

97.732

0.444
  comFA Latilactobacillus sakei subsp. sakei 23K

39.558

92.29

0.365