Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   I5W22_RS02055 Genome accession   NZ_CP065431
Coordinates   413996..414637 (+) Length   213 a.a.
NCBI ID   WP_002937025.1    Uniprot ID   A0A0H3MTV8
Organism   Streptococcus suis strain YP20190405     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 408996..419637
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I5W22_RS02035 (I5W22_02035) - 409164..409901 (+) 738 WP_012774983.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  I5W22_RS02040 (I5W22_02040) pknB 409901..411559 (+) 1659 Protein_362 Stk1 family PASTA domain-containing Ser/Thr kinase -
  I5W22_RS10710 - 411680..411895 (+) 216 Protein_363 serine/threonine protein kinase -
  I5W22_RS02045 (I5W22_02045) liaF 412352..413011 (+) 660 WP_223375661.1 cell wall-active antibiotics response protein LiaF -
  I5W22_RS02050 (I5W22_02050) - 413008..414024 (+) 1017 WP_002937028.1 sensor histidine kinase -
  I5W22_RS02055 (I5W22_02055) vraR 413996..414637 (+) 642 WP_002937025.1 response regulator transcription factor Regulator
  I5W22_RS02060 (I5W22_02060) - 414687..416087 (+) 1401 WP_011921996.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  I5W22_RS02065 (I5W22_02065) - 416089..416460 (+) 372 WP_011921997.1 S1 RNA-binding domain-containing protein -
  I5W22_RS02070 (I5W22_02070) cysK 416486..417412 (-) 927 WP_012774985.1 cysteine synthase A -
  I5W22_RS02075 (I5W22_02075) - 417502..418134 (-) 633 WP_014636235.1 YigZ family protein -
  I5W22_RS02080 (I5W22_02080) comFA/cflA 418191..419483 (+) 1293 WP_012774986.1 DEAD/DEAH box helicase Machinery gene

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 23790.36 Da        Isoelectric Point: 4.8970

>NTDB_id=447087 I5W22_RS02055 WP_002937025.1 413996..414637(+) (vraR) [Streptococcus suis strain YP20190405]
MNTIRVMLVDDHEMVRLGLKSYLNLQPDVEVVAEASDGEEGLAKALEVKPDVVVMDLVMPKMTGVEATLALLKEWPQAQI
VILTSYLDNEKIYPVLEAGARGYMLKTSSADEILAAIRKVALGEYAIETEVEKKVEHHKRHPDLHDDLTAREREILTLLA
KGYDNQRIADESFISLKTVKTHVSNILSKLAVSDRTQAVVYAFQHGLVAQEDQ

Nucleotide


Download         Length: 642 bp        

>NTDB_id=447087 I5W22_RS02055 WP_002937025.1 413996..414637(+) (vraR) [Streptococcus suis strain YP20190405]
ATGAATACGATTCGAGTGATGCTGGTTGACGACCATGAGATGGTTCGCCTAGGATTGAAAAGTTACTTAAATTTACAGCC
AGATGTTGAAGTAGTTGCAGAAGCTAGTGATGGCGAGGAAGGTTTGGCTAAAGCGTTAGAGGTTAAACCTGATGTTGTAG
TGATGGACTTGGTTATGCCCAAGATGACTGGCGTAGAAGCAACTCTGGCCTTGCTGAAGGAATGGCCGCAAGCGCAGATT
GTCATCCTGACCTCCTATCTAGATAATGAGAAAATCTATCCTGTGCTGGAAGCAGGAGCTCGTGGCTATATGTTGAAAAC
GTCAAGTGCTGACGAAATCTTAGCAGCCATCCGCAAGGTAGCTCTTGGAGAATATGCTATTGAGACAGAAGTAGAGAAAA
AAGTAGAGCACCATAAACGCCACCCAGATTTACATGATGACTTGACAGCTCGTGAACGCGAAATCTTGACGCTGTTAGCC
AAGGGATATGATAATCAACGAATTGCAGATGAGTCCTTCATATCCTTAAAAACTGTTAAGACCCATGTTTCCAATATCTT
ATCCAAACTAGCTGTTAGCGATCGTACTCAAGCAGTTGTTTATGCTTTCCAGCATGGTTTGGTGGCGCAAGAGGACCAAT
AG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(148-202)

Response regulator receiver domain (Response_reg)

(6-118)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H3MTV8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

54.589

97.183

0.531
  degU Bacillus subtilis subsp. subtilis str. 168

38.938

100

0.413