Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   I5V48_RS09280 Genome accession   NZ_CP065430
Coordinates   1969712..1970353 (-) Length   213 a.a.
NCBI ID   WP_043025113.1    Uniprot ID   -
Organism   Streptococcus suis strain YZDH1     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1964712..1975353
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I5V48_RS09255 (I5V48_09255) comFA/cflA 1964865..1966157 (-) 1293 WP_029185778.1 DEAD/DEAH box helicase Machinery gene
  I5V48_RS09260 (I5V48_09260) - 1966214..1966846 (+) 633 WP_043025119.1 YigZ family protein -
  I5V48_RS09265 (I5V48_09265) cysK 1966936..1967862 (+) 927 WP_043025117.1 cysteine synthase A -
  I5V48_RS09270 (I5V48_09270) - 1967889..1968260 (-) 372 WP_002937017.1 S1 RNA-binding domain-containing protein -
  I5V48_RS09275 (I5V48_09275) - 1968262..1969662 (-) 1401 WP_024377222.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  I5V48_RS09280 (I5V48_09280) vraR 1969712..1970353 (-) 642 WP_043025113.1 response regulator transcription factor Regulator
  I5V48_RS09285 (I5V48_09285) - 1970325..1971341 (-) 1017 WP_197315045.1 sensor histidine kinase -
  I5V48_RS09290 (I5V48_09290) liaF 1971338..1971997 (-) 660 WP_228377879.1 cell wall-active antibiotics response protein LiaF -
  I5V48_RS09295 (I5V48_09295) - 1972579..1973700 (-) 1122 WP_015445098.1 IS110 family transposase -
  I5V48_RS12365 - 1974034..1974306 (-) 273 WP_419992222.1 PASTA domain-containing protein -

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 23736.31 Da        Isoelectric Point: 5.0119

>NTDB_id=447034 I5V48_RS09280 WP_043025113.1 1969712..1970353(-) (vraR) [Streptococcus suis strain YZDH1]
MNTIRVMLVDDHEMVRLGLKSYLNLQSDVEVVAEASDGEEGLAKALEVKPDVVVMDLVMPKMTGVEATLALLKEWPQAQI
VILTSYLDNEKIYPVLEAGARGYMLKTSSADEILAAIRKVALGEYAIETEVEKKVEHHKRHPALHDDLTAREREILTLLA
KGYDNQRIADESFISLKTVKTHVSNILSKLAVSDRTQAVVYAFQHGLVAQEDQ

Nucleotide


Download         Length: 642 bp        

>NTDB_id=447034 I5V48_RS09280 WP_043025113.1 1969712..1970353(-) (vraR) [Streptococcus suis strain YZDH1]
ATGAATACGATTCGAGTGATGCTGGTTGACGACCATGAGATGGTCCGTCTAGGATTGAAAAGTTACTTAAATTTACAGTC
AGATGTTGAAGTAGTTGCAGAAGCTAGTGATGGCGAGGAAGGTTTGGCTAAAGCGTTAGAGGTTAAACCCGATGTTGTAG
TGATGGACTTGGTTATGCCCAAGATGACTGGCGTAGAAGCAACCCTGGCCTTGCTGAAGGAATGGCCGCAAGCGCAGATT
GTCATCCTGACCTCCTACCTAGATAATGAGAAAATCTATCCTGTGCTGGAAGCAGGAGCTCGTGGCTATATGTTGAAAAC
GTCAAGTGCTGACGAAATCTTAGCAGCCATCCGCAAGGTAGCTCTTGGAGAATATGCTATTGAGACAGAAGTAGAGAAAA
AAGTAGAGCACCATAAACGCCACCCAGCTTTACATGATGACTTGACAGCTCGTGAACGCGAAATCTTGACGCTGTTAGCC
AAGGGATACGATAATCAACGAATTGCAGATGAGTCCTTCATTTCCCTAAAAACTGTTAAGACCCATGTTTCCAATATCTT
ATCCAAACTAGCTGTTAGCGATCGTACTCAAGCAGTTGTTTATGCTTTCCAGCATGGTTTGGTGGCGCAAGAGGACCAAT
AG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(148-202)

Response regulator receiver domain (Response_reg)

(6-118)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

55.072

97.183

0.535
  degU Bacillus subtilis subsp. subtilis str. 168

39.648

100

0.423