Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   ST1A_RS06260 Genome accession   NZ_CP065384
Coordinates   1208762..1210549 (-) Length   595 a.a.
NCBI ID   WP_011681323.1    Uniprot ID   Q03K10
Organism   Streptococcus thermophilus strain 1A     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1203762..1215549
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ST1A_RS06240 (ST1A_06195) - 1204725..1205395 (-) 671 Protein_1175 DNA alkylation repair protein -
  ST1A_RS06245 (ST1A_06200) - 1205557..1206069 (-) 513 WP_011681320.1 GNAT family N-acetyltransferase -
  ST1A_RS06250 (ST1A_06205) - 1206229..1207030 (+) 802 Protein_1177 ISL3 family transposase -
  ST1A_RS06255 (ST1A_06210) cls 1207123..1208673 (-) 1551 WP_187145726.1 cardiolipin synthase -
  ST1A_RS06260 (ST1A_06215) uvrC 1208762..1210549 (-) 1788 WP_011681323.1 excinuclease ABC subunit UvrC Machinery gene
  ST1A_RS06265 (ST1A_06220) - 1210609..1211304 (-) 696 WP_011681324.1 YjjG family noncanonical pyrimidine nucleotidase -
  ST1A_RS06270 (ST1A_06225) sdaAB 1211582..1212253 (+) 672 WP_011681325.1 L-serine ammonia-lyase, iron-sulfur-dependent subunit beta -
  ST1A_RS06275 (ST1A_06230) sdaAA 1212266..1213135 (+) 870 WP_011226205.1 L-serine ammonia-lyase, iron-sulfur-dependent, subunit alpha -
  ST1A_RS06280 - 1213319..1213542 (+) 224 Protein_1183 IS30 family transposase -
  ST1A_RS06285 (ST1A_06235) - 1213859..1214428 (-) 570 WP_041827737.1 hypothetical protein -
  ST1A_RS06290 (ST1A_06240) - 1214571..1215355 (-) 785 Protein_1185 ABC transporter permease -

Sequence

Protein


Download         Length: 595 a.a.        Molecular weight: 68470.97 Da        Isoelectric Point: 9.6924

>NTDB_id=446650 ST1A_RS06260 WP_011681323.1 1208762..1210549(-) (uvrC) [Streptococcus thermophilus strain 1A]
MNGLIKHKLELLPSNPGCYLHKDKFGNIIYVGKAKNLKNRVRSYFRGSHDTKTELLVSEIADFEFIVTESNIEALLLEIN
LIQENMPKFNIRLKDGKSYPFIKITKELYPRLLITRQVKKDGGLYFGPYPDSGAANEIKKLLDRIFPFKKCKNPANKVCF
YYHIGQCNAHTICHTTEDYWQGLVEDVKNFLNGHDDKIVNQLKAKMKDMSDQMAFERAAEYRDLIEAVSTLRTKQRVIRQ
DMQDRDIFGYYVDKGWMCVQVFFVRQGKLIQRDVNMFPYYNDAEEDFLTYMGQFYLDSRHLKPKEIFIPGDIDQESVEAL
VGDEVKVFKPKRGEKKQLVNLATKNARVSLTQKFDLLEKDIAKTQGAIENLGKLMGIPTPVRIESFDNSNIMGTSPVSAM
VVFENGKPNKKEYRKYKIKTVEGPDDYASMREVIRRRYSRVKRDGLTPPDLIIMDGGQGQVNVAKDVLRNELNLSIPVAG
LQKNDKHQTNELLFGDPLRVIDLPRQSEEFFLLHRIQDEVHRFAITFHRQVRSKNSFSSKLDGVEGLGPKRKQKLLKNFK
SMTAIQQASVEDIQALGIPKKVAQALLDKLSQDSH

Nucleotide


Download         Length: 1788 bp        

>NTDB_id=446650 ST1A_RS06260 WP_011681323.1 1208762..1210549(-) (uvrC) [Streptococcus thermophilus strain 1A]
ATGAATGGTCTGATTAAACATAAGTTGGAACTGCTCCCAAGCAACCCAGGGTGTTATCTCCACAAGGACAAATTCGGCAA
TATTATTTATGTCGGTAAGGCTAAAAATCTAAAAAATCGTGTGCGTAGCTATTTTCGTGGAAGCCATGATACCAAGACGG
AGCTTTTGGTATCTGAGATTGCAGACTTTGAATTTATCGTAACCGAGTCTAATATCGAGGCCCTGCTTTTGGAAATTAAC
CTCATTCAAGAGAATATGCCCAAATTTAACATTCGCCTCAAGGATGGCAAGTCTTATCCATTTATCAAGATTACTAAGGA
ACTCTATCCAAGGCTCTTGATTACCCGCCAGGTTAAGAAGGATGGTGGTCTCTATTTTGGTCCTTACCCAGACTCTGGTG
CAGCCAATGAAATCAAGAAGCTGTTGGACCGTATTTTCCCCTTTAAGAAATGTAAAAATCCTGCTAACAAGGTCTGTTTC
TATTACCATATTGGCCAATGTAATGCCCACACCATCTGTCACACCACTGAGGACTATTGGCAAGGTTTGGTTGAGGATGT
CAAGAATTTTCTAAACGGTCATGATGATAAAATCGTTAACCAGCTTAAGGCCAAGATGAAGGACATGTCTGATCAGATGG
CGTTTGAGCGGGCAGCAGAATATCGAGATCTGATTGAGGCAGTGTCGACGCTCAGGACCAAACAAAGGGTTATCCGTCAA
GATATGCAGGACCGCGATATTTTTGGCTACTACGTGGACAAGGGCTGGATGTGTGTTCAAGTTTTCTTTGTTCGCCAAGG
AAAACTCATCCAGCGTGATGTCAATATGTTCCCTTACTATAATGATGCTGAGGAAGATTTTCTAACCTATATGGGTCAAT
TTTACTTGGATAGCCGTCATCTCAAGCCTAAGGAGATTTTCATTCCAGGGGACATTGATCAAGAGTCTGTCGAAGCTCTG
GTCGGAGATGAAGTCAAGGTTTTTAAACCGAAAAGAGGCGAGAAAAAGCAGTTGGTTAATCTGGCAACGAAAAATGCCCG
TGTCAGCCTGACTCAAAAATTTGATCTTCTTGAAAAAGATATAGCCAAGACCCAAGGAGCCATTGAAAATCTAGGCAAAC
TCATGGGAATTCCGACACCGGTTCGCATCGAGTCCTTCGATAACTCTAACATCATGGGAACGAGCCCTGTATCTGCCATG
GTCGTTTTTGAGAACGGCAAACCTAATAAAAAAGAGTACCGCAAATACAAGATTAAGACGGTTGAAGGTCCTGACGATTA
TGCCAGCATGCGTGAGGTCATTCGTCGCCGTTATAGTCGTGTCAAACGTGATGGTCTAACCCCACCAGACCTCATTATCA
TGGATGGTGGTCAAGGTCAGGTCAATGTCGCTAAGGACGTGCTTCGTAATGAGCTGAATCTATCTATCCCGGTTGCAGGT
CTTCAGAAAAATGACAAGCACCAAACCAATGAATTGCTCTTTGGAGATCCTTTGCGAGTCATTGATTTGCCACGTCAATC
CGAGGAGTTTTTCCTCCTTCACCGTATTCAGGATGAAGTACACCGCTTTGCCATCACCTTCCATCGACAAGTCCGTAGTA
AGAATAGTTTCAGTTCCAAACTTGATGGCGTGGAGGGGTTGGGACCTAAACGCAAACAAAAACTCCTCAAAAACTTCAAA
TCAATGACAGCTATCCAACAAGCCAGTGTCGAAGACATCCAAGCTCTTGGAATTCCTAAAAAAGTAGCTCAAGCTTTATT
AGATAAGTTGAGCCAAGATAGTCATTAA

Domains

Predicted by InterProScan.

GIY-YIG catalytic domain (GIY-YIG)

(16-87)

UvrB/uvrC motif (UVR)

(196-229)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(375-525)

Helix-hairpin-helix domain (HHH_5)

(540-590)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q03K10

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae TIGR4

75.804

99.328

0.753
  uvrC Streptococcus pneumoniae R6

75.465

99.328

0.75
  uvrC Streptococcus pneumoniae D39

75.465

99.328

0.75