Detailed information NTG0446597

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: HNV93_RS14870
• Genome accession: NZ_CP053717
• Coordinates: 3068220..3069383 (+)
• Length: 387 a.a.
• NCBI ID: WP_007407484.1
• Uniprot ID: A3KLC1
• Organism: Bacillus velezensis strain A2
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 3063220..3074383

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HNV93_RS14850	-	3063660..3064856 (+)	1197	WP_032876154.1	glycosyltransferase	-
HNV93_RS14855	-	3064989..3066065 (+)	1077	WP_003151382.1	glycosyltransferase family 4 protein	-
HNV93_RS14860	-	3066164..3067345 (-)	1182	WP_032876157.1	LCP family protein	-
HNV93_RS14865	-	3067350..3067997 (-)	648	WP_007614107.1	YigZ family protein	-
HNV93_RS14870	degS	3068220..3069383 (+)	1164	WP_007407484.1	two-component sensor histidine kinase DegS	Regulator
HNV93_RS14875	degU	3069460..3070149 (+)	690	WP_003219701.1	two-component system response regulator DegU	Regulator
HNV93_RS14880	-	3070247..3071095 (+)	849	WP_032876160.1	DegV family protein	-
HNV93_RS14885	comFA	3071204..3072589 (+)	1386	WP_032876163.1	DEAD/DEAH box helicase	Machinery gene
HNV93_RS14890	-	3072647..3072931 (+)	285	WP_003151389.1	competence protein ComFB	-
HNV93_RS14895	comFC	3072937..3073626 (+)	690	WP_196770545.1	phosphoribosyltransferase family protein	Machinery gene
HNV93_RS14900	-	3073700..3074119 (+)	420	WP_012118571.1	TIGR03826 family flagellar region protein	-

Sequence

Protein

• Length: 387 a.a.
• Molecular weight: 45014.78 Da
• Isoelectric Point: 6.8616

>NTDB_id=446597 HNV93_RS14870 WP_007407484.1 3068220..3069383(+) (degS) [Bacillus velezensis strain A2]
MNKSKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVHTRHARNRLSEVSR
NFHKFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLRQVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGTEDGFQEIRNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGDTENQRLAPQFEVALFRLAQEAVTNALKHSESEEITVKVEV
TADFVVLIIKDNGKGFDIKDAKQKKNKSFGLLGMKERVDLLEGTITIDSKIGLGTFIMIKVPLSLGL

Nucleotide

• Length: 1164 bp

>NTDB_id=446597 HNV93_RS14870 WP_007407484.1 3068220..3069383(+) (degS) [Bacillus velezensis strain A2]
ATGAATAAATCGAAGATGGACTCCAAAGTTTTGGATTCTATACTTATGAAAATGCTGAAAACCGTGGACGGGAGCAAGGA
CGAGGTTTTTCAAATCGGAGAGCAGTCGCGCCAGCAATATGAGCAGCTGGTTGAAGAACTCAAACAGATCAAACAGCAGG
TGTACGAAGTCATTGAGCTGGGCGACAAACTTGAAGTTCATACGCGGCACGCACGAAACCGCTTGTCTGAAGTAAGCAGA
AATTTCCATAAGTTCAGCGAAGAAGAAATTCGCAACGCCTATGAAAAGGCGCACAAACTTCAAGTGGAACTGACGATGAT
CCAGCAGCGTGAAAAGCAGCTGCGGGAGCGCAGAGATGATTTAGAACGCCGGCTTTTGGGGCTTCAGGAAATTATTGAAC
GGTCAGAATCATTGGTCAGCCAAATAACCGTCGTTCTGAATTACCTGAATCAAGACCTTCGCCAAGTAGGGCTTCTTCTT
GCCGATGCGCAGGCTAAACAAGATTTCGGTTTAAGAATCATTGAAGCCCAAGAGGAAGAAAGAAAAAGAGTTTCCAGAGA
AATTCATGACGGTCCCGCGCAAATGCTGGCAAATGTCATGATGAGATCGGAATTAATTGAACGGATCTTCCGCGACCGCG
GCACGGAGGACGGATTTCAGGAAATCAGAAATCTACGGCAGAATGTGCGGAATGCCCTTTACGAAGTCAGAAGGATTATA
TATGATTTAAGACCGATGGCATTGGACGATCTCGGGCTGATTCCGACACTGAGAAAATATCTTTATACAACTGAAGAATA
CAACGGAAAGGTGAAAATACATTTTCAGTGCATCGGAGACACAGAGAACCAAAGGCTTGCCCCGCAATTTGAAGTGGCGC
TTTTCCGTCTCGCTCAGGAAGCCGTCACAAATGCACTCAAGCATTCAGAATCAGAGGAAATTACAGTAAAAGTGGAAGTA
ACCGCTGATTTTGTCGTTCTCATCATTAAGGACAATGGAAAAGGCTTTGATATTAAGGATGCTAAACAAAAGAAAAACAA
GTCATTCGGCTTGCTGGGAATGAAAGAAAGAGTAGATCTGCTTGAAGGAACGATAACGATAGACTCTAAAATAGGTCTTG
GGACATTTATCATGATTAAGGTTCCGTTATCTCTCGGCCTATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

• Histidine kinase (HisKA_3) (180-248)

3D structure

• AlphaFold DB: A3KLC1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	95.584	99.483	0.951