Detailed information NTG0446496

Bioinformatically predicted

Overview

• Name: clpX
• Type: Regulator
• Locus tag: I3251_RS02650
• Genome accession: NZ_CP065374
• Coordinates: 589436..590716 (-)
• Length: 426 a.a.
• NCBI ID: WP_003087924.1
• Uniprot ID: Q02KU5
• Organism: Pseudomonas aeruginosa strain PAG7
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 584436..595716

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I3251_RS02640 (I3251_02640)	hupB	586500..586772 (-)	273	WP_003087931.1	nucleoid-associated protein HU-beta	-
I3251_RS02645 (I3251_02645)	lon	586908..589304 (-)	2397	WP_003087926.1	endopeptidase La	-
I3251_RS02650 (I3251_02650)	clpX	589436..590716 (-)	1281	WP_003087924.1	ATP-dependent Clp protease ATP-binding subunit ClpX	Regulator
I3251_RS02655 (I3251_02655)	clpP	590821..591462 (-)	642	WP_003098129.1	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	Regulator
I3251_RS02660 (I3251_02660)	tig	591556..592866 (-)	1311	WP_003087920.1	trigger factor	-
I3251_RS02665 (I3251_02665)	parR	593098..593805 (+)	708	WP_003098126.1	response regulator transcription factor ParR	-
I3251_RS02670 (I3251_02670)	parS	593806..595092 (+)	1287	WP_003087912.1	sensor histidine kinase ParS	-

Sequence

Protein

• Length: 426 a.a.
• Molecular weight: 46991.78 Da
• Isoelectric Point: 4.8347

>NTDB_id=446496 I3251_RS02650 WP_003087924.1 589436..590716(-) (clpX) [Pseudomonas aeruginosa strain PAG7]
MTDTRNGEDNGKLLYCSFCGKSQHEVRKLIAGPSVFICDECVDLCNDIIREEVQEAQAESSGHKLPAPKEIRTILDQYVI
GQERAKKVLAVAVYNHYKRLNQRDKKDDIELGKSNILMIGPTGSGKTLLAETLARLLNVPFTIADATTLTEAGYVGEDVE
NIIQKLLQKCDYDVEKAQMGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTVASVPPQGGRKHPQQEFLQVD
TRNILFICGGAFAGLERVIQNRSARGGIGFNAEVRSQEMGKKVGEAFKEVEPEDLVKFGLIPEFVGRLPVIATLDELDEA
ALMQILTEPKNALTKQYAKLFEMEGVDLEFRPDALKAVARKALERKTGARGLRSILEGILLDTMYEIPSQQDVSKVVIDE
SVIDGSSQPLMIYENSEKPAKAAPEA

Nucleotide

• Length: 1281 bp

>NTDB_id=446496 I3251_RS02650 WP_003087924.1 589436..590716(-) (clpX) [Pseudomonas aeruginosa strain PAG7]
ATGACTGATACCCGCAACGGCGAGGACAACGGCAAGCTGCTGTATTGCTCCTTCTGCGGCAAGAGCCAGCACGAAGTGCG
CAAGTTGATTGCCGGCCCCTCGGTCTTTATCTGCGACGAGTGTGTCGACCTGTGCAATGACATCATCCGCGAGGAGGTGC
AGGAAGCGCAGGCGGAAAGTAGTGGGCACAAACTTCCGGCGCCGAAAGAGATCCGCACCATCCTCGATCAGTACGTGATC
GGGCAGGAGCGGGCCAAGAAGGTTCTGGCGGTAGCGGTATACAACCACTACAAGCGCCTCAACCAGCGTGACAAGAAGGA
CGATATCGAGCTCGGCAAGAGCAACATTCTGATGATCGGCCCAACCGGCTCGGGCAAGACCCTGCTGGCCGAGACCCTCG
CACGTCTGCTGAACGTGCCGTTCACCATCGCCGATGCGACCACGCTGACGGAAGCGGGCTACGTGGGCGAGGATGTCGAG
AACATCATCCAGAAGCTCTTGCAGAAGTGCGATTACGATGTGGAGAAGGCCCAGATGGGCATCGTCTACATCGACGAGAT
CGACAAGATCTCCCGGAAATCGGACAATCCCTCCATCACTCGCGACGTTTCCGGCGAGGGTGTGCAGCAGGCCCTGCTGA
AGCTCATCGAGGGCACCGTTGCCTCGGTACCGCCGCAGGGCGGTCGCAAGCATCCGCAGCAGGAGTTCCTGCAGGTCGAT
ACGCGCAACATCCTGTTCATCTGCGGCGGCGCTTTCGCCGGTCTGGAGCGGGTCATCCAGAACCGTTCCGCGCGCGGCGG
CATCGGTTTCAATGCCGAAGTGCGCAGTCAGGAGATGGGCAAGAAGGTCGGCGAGGCGTTCAAGGAAGTCGAACCGGAAG
ATCTCGTCAAGTTCGGTCTTATTCCCGAGTTTGTAGGGCGTTTGCCGGTGATCGCGACTCTTGATGAGCTCGACGAGGCT
GCGCTCATGCAGATCCTGACCGAGCCGAAGAACGCTCTCACCAAGCAGTACGCCAAGCTGTTCGAAATGGAAGGCGTCGA
TCTCGAATTCCGTCCGGACGCACTCAAGGCGGTTGCCCGCAAGGCGCTCGAACGCAAGACCGGTGCACGTGGCTTGCGTT
CAATTCTCGAAGGTATCCTTCTCGATACCATGTACGAGATTCCCTCCCAGCAGGATGTCAGCAAGGTGGTCATCGATGAG
AGTGTCATCGATGGCTCGTCGCAACCCCTGATGATCTACGAGAACAGCGAAAAGCCAGCCAAGGCTGCGCCTGAGGCATG
A

Domains

Predicted by InterProScan.

• ClpX C4-type zinc finger (zf-C4_ClpX) (14-51)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (317-395)

• AAA domain (Cdc48 subfamily) (AAA_2) (113-311)

3D structure

• AlphaFold DB: Q02KU5

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpX	Streptococcus mutans UA159	60.934	95.54	0.582
clpX	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	55.198	94.836	0.523