Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   I3U01_RS09440 Genome accession   NZ_CP065203
Coordinates   1919665..1920321 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain EC-10     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1914665..1925321
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I3U01_RS09410 (I3U01_09295) dcyD 1915546..1916532 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  I3U01_RS09415 (I3U01_09300) tcyL 1916547..1917215 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  I3U01_RS09420 (I3U01_09305) tcyN 1917212..1917964 (+) 753 WP_063624912.1 L-cystine ABC transporter ATP-binding protein TcyN -
  I3U01_RS09425 (I3U01_09310) sdiA 1918194..1918916 (+) 723 WP_001154255.1 transcriptional regulator SdiA -
  I3U01_RS09430 (I3U01_09315) yecF 1918983..1919207 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  I3U01_RS09435 (I3U01_09320) yecU 1919194..1919370 (-) 177 WP_032245964.1 protein YecU -
  I3U01_RS09440 (I3U01_09325) letA 1919665..1920321 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  I3U01_RS09445 (I3U01_09330) uvrC 1920318..1922150 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  I3U01_RS09450 (I3U01_09335) pgsA 1922207..1922755 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  I3U01_RS09470 (I3U01_09355) yecA 1923405..1924070 (+) 666 WP_000847877.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=446077 I3U01_RS09440 WP_000611328.1 1919665..1920321(+) (letA) [Escherichia coli strain EC-10]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=446077 I3U01_RS09440 WP_000611328.1 1919665..1920321(+) (letA) [Escherichia coli strain EC-10]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGCCTTGAGGCAACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACTGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCTGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCTGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CATTAAGCCAGATCGAACCAGAAAAAACAGAAAGTCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACTAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482