Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   I2T83_RS10465 Genome accession   NZ_CP065136
Coordinates   2191823..2192479 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain EE72d     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2186823..2197479
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I2T83_RS10435 (I2T83_10435) dcyD 2187703..2188689 (+) 987 WP_020232905.1 D-cysteine desulfhydrase -
  I2T83_RS10440 (I2T83_10440) tcyL 2188704..2189372 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  I2T83_RS10445 (I2T83_10445) tcyN 2189369..2190121 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  I2T83_RS10450 (I2T83_10450) sdiA 2190351..2191073 (+) 723 WP_001154271.1 transcriptional regulator SdiA -
  I2T83_RS10455 (I2T83_10455) yecF 2191140..2191364 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  I2T83_RS10460 (I2T83_10460) yecU 2191351..2191527 (-) 177 WP_000590347.1 protein YecU -
  I2T83_RS10465 (I2T83_10465) letA 2191823..2192479 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  I2T83_RS10470 (I2T83_10470) uvrC 2192476..2194308 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  I2T83_RS10475 (I2T83_10475) pgsA 2194365..2194913 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  I2T83_RS10495 (I2T83_10495) yecA 2195563..2196228 (+) 666 WP_000847881.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=445595 I2T83_RS10465 WP_000611328.1 2191823..2192479(+) (letA) [Escherichia coli strain EE72d]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=445595 I2T83_RS10465 WP_000611328.1 2191823..2192479(+) (letA) [Escherichia coli strain EE72d]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAATGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCTGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATCCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482