Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   ITP52_RS01530 Genome accession   NZ_CP064818
Coordinates   364963..366846 (-) Length   627 a.a.
NCBI ID   WP_041850821.1    Uniprot ID   -
Organism   Bacillus subtilis strain SH1     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 359963..371846
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ITP52_RS01500 (ITP52_01500) fabD 360553..361419 (-) 867 WP_015715909.1 ACP S-malonyltransferase -
  ITP52_RS01505 (ITP52_01505) - 361416..361682 (-) 267 WP_120363368.1 hypothetical protein -
  ITP52_RS01510 (ITP52_01510) pksB 361793..362470 (-) 678 WP_029726478.1 MBL fold metallo-hydrolase -
  ITP52_RS01515 (ITP52_01515) pksA 362659..363276 (-) 618 WP_021479267.1 TetR/AcrR family transcriptional regulator -
  ITP52_RS01520 (ITP52_01520) - 363397..363954 (+) 558 WP_038428985.1 hypothetical protein -
  ITP52_RS01525 (ITP52_01525) ymzD 364109..364564 (+) 456 WP_080332606.1 regulatory YrvL family protein -
  ITP52_RS01530 (ITP52_01530) hexB 364963..366846 (-) 1884 WP_041850821.1 DNA mismatch repair endonuclease MutL Machinery gene
  ITP52_RS01535 (ITP52_01535) mutS 366862..369437 (-) 2576 Protein_307 DNA mismatch repair protein MutS -
  ITP52_RS01540 (ITP52_01540) cotE 369570..370115 (-) 546 WP_003231833.1 outer spore coat protein CotE -
  ITP52_RS01545 (ITP52_01545) ymcA 370377..370808 (-) 432 WP_003231834.1 regulatory iron-sulfur-containing complex subunit RicA Regulator

Sequence

Protein


Download         Length: 627 a.a.        Molecular weight: 70402.43 Da        Isoelectric Point: 6.0358

>NTDB_id=444934 ITP52_RS01530 WP_041850821.1 364963..366846(-) (hexB) [Bacillus subtilis strain SH1]
MAKVIQLSDELSNKIAAGEVVERPASVVKELVENAIDADSTVIEIDIEEAGLASIRVLDNGEGMENEDCKRAFRRHATSK
IKDENDLFRVRTLGFRGEALPSIASVSHLEITTSTGEGAGTKLVLQGGNIISESRSSSRKGTEIVVSNLFFNTPARLKYM
KTVHTELGNITDVVNRIALAHPEVSIRLRHHGKNLLQTNGNGDVRHVLAAIYGTAVAKKMLPLHASSLDFEVKGYIALPE
ITRASRNYMSSVVNGRYIKNFPLVKAVHEGYHTLLPIGRHPITFIEITMDPILVDVNVHPSKLEVRLSKETELHDLIRDG
IKDVFKQQQLIPSAQLPKKSAPVIKNEQQFITFDEKPPEKKVPEKSTAPSYSPMKLSSVVKEPVDAEEELPPLQFDAPPI
VDQKQILEVSDVSAKEPDTFEQECHEGQQQPASERVPIMYPIGQMHGTYILAQNENGLYIIDQHAAQERIKYEYFREKVG
EVEPEVQDMIVPLTFHYSTNEALIIEQHKQELESVGVFLESFGSNSYIVRCHPAWFPKGEEAELIEEIIQQVLDSKNIDI
KKLREEAAIMMSCKGSIKANRHLRNDEIKALLDDLRSTSDPFTCPHGRPIIIHHSTYEMEKMFKRVM

Nucleotide


Download         Length: 1884 bp        

>NTDB_id=444934 ITP52_RS01530 WP_041850821.1 364963..366846(-) (hexB) [Bacillus subtilis strain SH1]
GTGGCAAAAGTCATCCAACTGTCAGATGAGCTTTCAAATAAAATAGCGGCGGGCGAGGTTGTGGAACGGCCCGCCTCAGT
CGTCAAAGAATTGGTGGAAAATGCGATCGACGCTGACAGCACAGTCATTGAAATCGATATTGAGGAAGCAGGCCTTGCAT
CCATTCGGGTCTTGGATAACGGCGAAGGAATGGAGAATGAAGATTGCAAGCGAGCTTTCCGCCGCCACGCAACGAGTAAA
ATAAAAGATGAAAATGATTTATTCAGGGTGAGAACGCTCGGTTTCAGGGGAGAAGCCCTGCCGAGTATCGCGTCAGTCTC
TCATCTGGAGATTACAACAAGCACTGGTGAAGGAGCTGGGACGAAGCTCGTCCTCCAAGGAGGAAACATCATTTCCGAAT
CGCGTTCCTCAAGCAGGAAGGGAACTGAAATTGTCGTTTCCAACCTGTTTTTTAACACACCGGCCCGTTTGAAATATATG
AAAACCGTTCATACAGAGCTTGGAAACATTACGGATGTGGTTAACCGTATTGCTCTGGCGCATCCAGAGGTATCGATCCG
CCTGCGCCATCATGGGAAAAACCTGCTTCAAACGAACGGAAACGGAGATGTGCGCCATGTACTGGCAGCGATTTACGGCA
CGGCTGTCGCCAAAAAAATGCTTCCGCTGCATGCGAGCTCCTTGGATTTTGAAGTAAAGGGATATATCGCCCTCCCAGAG
ATTACACGGGCGTCGAGAAACTATATGTCGTCTGTGGTCAATGGCCGTTACATTAAAAATTTCCCGCTCGTCAAAGCGGT
TCATGAAGGCTATCATACGCTTCTGCCGATCGGACGCCATCCGATTACTTTTATAGAAATTACGATGGACCCGATTTTAG
TCGATGTCAACGTGCATCCATCGAAGCTTGAGGTCCGGCTCAGCAAGGAAACAGAGCTTCATGACTTAATTCGTGACGGA
ATTAAAGATGTATTTAAACAGCAGCAGCTGATTCCGAGTGCCCAGCTCCCGAAAAAATCGGCACCTGTTATCAAAAATGA
GCAGCAGTTCATAACCTTTGATGAAAAGCCTCCGGAAAAAAAAGTTCCGGAAAAATCGACTGCGCCATCTTATTCACCAA
TGAAGCTCAGCTCAGTCGTGAAAGAGCCGGTTGATGCGGAGGAAGAATTGCCACCTCTCCAATTTGATGCTCCTCCTATC
GTTGATCAGAAACAAATCCTTGAGGTGTCCGATGTTTCAGCGAAAGAGCCAGATACATTTGAGCAGGAATGCCATGAGGG
ACAGCAGCAGCCAGCGTCTGAGCGGGTTCCGATTATGTACCCGATCGGCCAGATGCACGGGACTTATATATTGGCACAAA
ACGAAAACGGCCTGTATATTATCGACCAGCACGCCGCCCAAGAACGTATTAAATATGAGTACTTTCGTGAAAAGGTGGGG
GAGGTTGAGCCTGAGGTGCAGGATATGATTGTACCGCTGACGTTCCACTACTCCACAAATGAGGCTTTGATTATTGAACA
GCACAAACAAGAGCTCGAAAGCGTCGGTGTCTTTTTAGAGTCATTCGGCTCCAACAGTTACATCGTCCGCTGCCACCCGG
CCTGGTTTCCAAAGGGAGAAGAAGCAGAGCTTATAGAAGAAATCATTCAGCAGGTGCTCGACTCCAAAAATATAGATATT
AAAAAACTCCGCGAGGAAGCGGCGATTATGATGAGCTGCAAAGGCTCCATCAAAGCAAATCGCCACCTCAGAAACGATGA
AATCAAAGCGCTTCTCGACGACCTCCGAAGCACATCAGACCCATTTACATGCCCGCACGGCCGCCCGATCATCATACACC
ATTCCACTTATGAGATGGAAAAGATGTTCAAACGCGTGATGTAG

Domains

Predicted by InterProScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-124)

MutL C terminal dimerisation domain (MutL_C)

(442-583)

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(209-324)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

46.047

100

0.474