Detailed information NTG0444925

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: EYQ96_RS06315
• Genome accession: NZ_CP053477
• Coordinates: 1203513..1204556 (+)
• Length: 347 a.a.
• NCBI ID: WP_002452288.1
• Uniprot ID: A0A2T4Q1J8
• Organism: Staphylococcus warneri strain WB224
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1198513..1209556

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EYQ96_RS06290 (EYQ96_06310)	-	1199570..1200295 (+)	726	WP_023373124.1	type 1 glutamine amidotransferase	-
EYQ96_RS06295 (EYQ96_06315)	-	1200362..1201348 (-)	987	WP_023373122.1	aromatic acid exporter family protein	-
EYQ96_RS06300 (EYQ96_06320)	map	1201515..1202270 (+)	756	WP_023373120.1	type I methionyl aminopeptidase	-
EYQ96_RS06305 (EYQ96_06325)	-	1202414..1202800 (+)	387	WP_023373118.1	DUF2543 family protein	-
EYQ96_RS06310 (EYQ96_06330)	liaF	1202815..1203516 (+)	702	WP_023373116.1	cell wall-active antibiotics response protein LiaF	-
EYQ96_RS06315 (EYQ96_06335)	vraS	1203513..1204556 (+)	1044	WP_002452288.1	sensor histidine kinase	Regulator
EYQ96_RS06320 (EYQ96_06340)	vraR	1204546..1205175 (+)	630	WP_002466112.1	two-component system response regulator VraR	Regulator
EYQ96_RS06325 (EYQ96_06345)	-	1205234..1206469 (-)	1236	WP_023373114.1	YihY/virulence factor BrkB family protein	-
EYQ96_RS06330 (EYQ96_06350)	-	1206697..1206981 (-)	285	WP_002466132.1	YtxH domain-containing protein	-
EYQ96_RS06335 (EYQ96_06355)	-	1206988..1207452 (-)	465	WP_023373112.1	low molecular weight protein-tyrosine-phosphatase	-
EYQ96_RS06340 (EYQ96_06360)	-	1207599..1207802 (+)	204	WP_041613607.1	DUF1128 domain-containing protein	-
EYQ96_RS06345 (EYQ96_06365)	-	1207815..1209056 (+)	1242	WP_023373108.1	aminopeptidase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40101.60 Da
• Isoelectric Point: 6.2449

>NTDB_id=444925 EYQ96_RS06315 WP_002452288.1 1203513..1204556(+) (vraS) [Staphylococcus warneri strain WB224]
MNHYIRAIGSMLILIYSMLTAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNIIVILLCIIVGSVLAYKINQQNDWIKT
QIERSIEGETVGINDQNIELYSETLEIYHTLVPLNQELHRLRMKTQNLTNENYNMNDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETQLEPPLDQQIPVLEKMIQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QEFKVPKGIEDHLFRITQEAISNTLRHSNGTRVTVELFNKQDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYGD

Nucleotide

• Length: 1044 bp

>NTDB_id=444925 EYQ96_RS06315 WP_002452288.1 1203513..1204556(+) (vraS) [Staphylococcus warneri strain WB224]
ATGAACCACTATATAAGAGCTATTGGGTCTATGCTGATATTGATATATAGTATGTTAACGGCGTTCTTATTTATTGATAA
AGTTTTTGTCAACATCATTTACTTTCAAGGCATGTTTTATACACAAATTTTCGGTATTCCAGTGTTCTTATTTTTAAATA
TTATAGTTATATTATTATGTATTATAGTAGGGTCAGTTTTAGCATATAAAATTAATCAACAGAATGATTGGATTAAAACT
CAAATTGAGCGATCAATTGAAGGGGAAACTGTTGGAATTAATGACCAAAATATTGAATTGTATAGCGAGACGTTGGAAAT
ATATCACACACTCGTTCCATTAAATCAAGAGTTACATCGATTAAGAATGAAAACACAAAATTTAACTAACGAAAATTATA
ATATGAATGATGTTAAAGTTAAAAAAATTATTGAAGATGAGCGACAACGCTTAGCTAGGGAATTGCATGATTCTGTAAGC
CAACAATTATTTGCAGCAAGTATGATGTTATCAGCAATAAAAGAAACACAGTTAGAACCACCATTAGATCAACAAATACC
CGTTCTTGAAAAAATGATTCAAGATTCACAACTTGAAATGAGAGCATTGTTACTTCATTTAAGACCACTAGGATTAAAAG
ATAAATCATTAGGTGAAGGTATTAAAGATTTAGTCATTGACCTTCAAAAGAAAGTACCAATGAAAGTAGTCCATGAAATC
CAAGAATTTAAAGTACCAAAAGGAATAGAAGATCATTTATTCAGAATCACACAAGAAGCAATTTCAAATACTTTGAGACA
TTCTAATGGTACAAGAGTAACGGTTGAATTATTTAATAAGCAAGATTATCTACTTTTACGTATACAAGATAATGGTAAAG
GTTTTAATGTAGATGAGAAACTTGAACAAAGCTATGGATTAAAGAATATGCGTGAACGTGCACTAGAAATTGGTGCCACA
TTCCATATCGTATCATTACCAGACTCTGGTACACGTATTGAAGTTAAAGCACCATTAAACAAGGAGGATTCGTATGGCGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase (HisKA_3) (147-210)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

3D structure

• AlphaFold DB: A0A2T4Q1J8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	94.524	100	0.945