Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB8   Type   Machinery gene
Locus tag   HK441_RS01140 Genome accession   NZ_CP053394
Coordinates   250026..250763 (+) Length   245 a.a.
NCBI ID   WP_001916845.1    Uniprot ID   A0AAE7DV68
Organism   Helicobacter pylori strain HP1352     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 245026..255763
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HK441_RS01115 (HK441_01115) panD 247184..247537 (+) 354 WP_001916849.1 aspartate 1-decarboxylase -
  HK441_RS01120 (HK441_01120) - 247540..247842 (+) 303 WP_000347926.1 YbaB/EbfC family nucleoid-associated protein -
  HK441_RS01125 (HK441_01125) - 247842..248837 (+) 996 WP_001916848.1 PDZ domain-containing protein -
  HK441_RS01130 (HK441_01130) comB6 248845..249900 (+) 1056 WP_171407256.1 P-type conjugative transfer protein TrbL Machinery gene
  HK441_RS01135 (HK441_01135) comB7 249916..250029 (+) 114 WP_001217868.1 hypothetical protein Machinery gene
  HK441_RS01140 (HK441_01140) comB8 250026..250763 (+) 738 WP_001916845.1 virB8 family protein Machinery gene
  HK441_RS01145 (HK441_01145) comB9 250763..251740 (+) 978 WP_001916844.1 TrbG/VirB9 family P-type conjugative transfer protein Machinery gene
  HK441_RS01150 (HK441_01150) comB10 251733..252869 (+) 1137 WP_001916843.1 DNA type IV secretion system protein ComB10 Machinery gene
  HK441_RS01155 (HK441_01155) - 252940..254352 (+) 1413 WP_001916842.1 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase -
  HK441_RS01160 (HK441_01160) gmd 254382..255527 (+) 1146 WP_001916841.1 GDP-mannose 4,6-dehydratase -

Sequence

Protein


Download         Length: 245 a.a.        Molecular weight: 28485.68 Da        Isoelectric Point: 8.9546

>NTDB_id=444748 HK441_RS01140 WP_001916845.1 250026..250763(+) (comB8) [Helicobacter pylori strain HP1352]
MKEKPFNSEQLIYLEELLSHQEKHLENKLSGFSVSDLDMQSVFRLERNRLKIAYKLLGLMSFIALILAIVLISVLPLQKT
EHHFVDFLNQDKHYAIIQRADKSISSNEALARSLIGAYVLNRESINRIDDKSRYELVRLQSSSKVWQRFEDLIKTQNSIY
AQSHLEREVHIVNIAIYQQDNNPIASVSIAAKLLNENKLVYEKRYKIVLSYLFDTPDFDYASMPKNPTGFKVTRYSITEI
TNRGD

Nucleotide


Download         Length: 738 bp        

>NTDB_id=444748 HK441_RS01140 WP_001916845.1 250026..250763(+) (comB8) [Helicobacter pylori strain HP1352]
ATGAAAGAAAAGCCTTTCAATAGCGAGCAGTTGATCTATTTAGAAGAGCTTTTAAGCCACCAAGAAAAGCATTTAGAAAA
CAAGCTTTCTGGTTTTTCGGTAAGTGATTTGGACATGCAAAGCGTGTTCAGATTGGAGAGAAACCGCTTGAAAATCGCTT
ATAAACTCTTAGGCTTGATGAGTTTTATCGCTCTTATCTTAGCGATCGTGTTAATCAGTGTTCTACCCTTACAAAAAACC
GAACACCATTTCGTGGATTTTTTAAATCAGGACAAGCATTACGCCATTATCCAAAGAGCGGATAAAAGCATTTCTAGTAA
TGAAGCGTTGGCTCGTTCGCTCATTGGGGCGTATGTGTTAAACCGAGAGAGCATTAACCGCATTGATGATAAATCGCGCT
ATGAATTGGTGCGCTTGCAAAGCAGTTCTAAAGTGTGGCAACGCTTTGAAGATTTGATTAAAACCCAAAACAGCATTTAT
GCGCAAAGCCATTTAGAAAGAGAAGTCCATATCGTCAATATTGCGATCTATCAGCAAGACAATAACCCCATTGCGAGCGT
GTCCATTGCGGCTAAACTTTTGAACGAAAACAAGCTCGTGTATGAAAAGCGTTATAAAATCGTATTGAGTTATTTGTTTG
ACACCCCGGATTTTGATTACGCTTCCATGCCTAAAAACCCTACCGGCTTTAAAGTTACTCGCTACAGCATCACTGAAATC
ACTAATAGGGGCGATTGA

Domains

Predicted by InterproScan.

VirB8 protein (VirB8)

(38-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB8 Helicobacter pylori P1

97.571

100

0.984