Detailed information    

insolico Bioinformatically predicted

Overview

Name   sigH   Type   Regulator
Locus tag   HA035_RS06170 Genome accession   NZ_CP053353
Coordinates   1253364..1253933 (+) Length   189 a.a.
NCBI ID   WP_000872873.1    Uniprot ID   -
Organism   Staphylococcus aureus strain 16405     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1248364..1258933
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HA035_RS06145 (HA035_06145) cysE 1249577..1250224 (+) 648 WP_001805237.1 serine O-acetyltransferase -
  HA035_RS06150 (HA035_06150) cysS 1250208..1251608 (+) 1401 WP_000631963.1 cysteine--tRNA ligase -
  HA035_RS06155 (HA035_06155) - 1251601..1252005 (+) 405 WP_000370182.1 Mini-ribonuclease 3 -
  HA035_RS06160 (HA035_06160) rlmB 1252013..1252759 (+) 747 WP_000390328.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
  HA035_RS06165 (HA035_06165) - 1252759..1253283 (+) 525 WP_000664738.1 NYN domain-containing protein -
  HA035_RS06170 (HA035_06170) sigH 1253364..1253933 (+) 570 WP_000872873.1 RNA polymerase sigma factor Regulator
  HA035_RS06175 (HA035_06175) rpmG 1254048..1254191 (+) 144 WP_001788193.1 50S ribosomal protein L33 -
  HA035_RS06180 (HA035_06180) secE 1254247..1254429 (+) 183 WP_001074474.1 preprotein translocase subunit SecE -
  HA035_RS06185 (HA035_06185) nusG 1254442..1254990 (+) 549 WP_001288302.1 transcription termination/antitermination protein NusG -
  HA035_RS06190 (HA035_06190) rplK 1255171..1255593 (+) 423 WP_001085792.1 50S ribosomal protein L11 -
  HA035_RS06195 (HA035_06195) rplA 1255801..1256493 (+) 693 WP_001074619.1 50S ribosomal protein L1 -
  HA035_RS06200 (HA035_06200) rplJ 1256765..1257265 (+) 501 WP_001273085.1 50S ribosomal protein L10 -
  HA035_RS06205 (HA035_06205) rplL 1257308..1257676 (+) 369 WP_001273586.1 50S ribosomal protein L7/L12 -
  HA035_RS06210 (HA035_06210) - 1257851..1258459 (+) 609 WP_000020304.1 class I SAM-dependent methyltransferase -

Sequence

Protein


Download         Length: 189 a.a.        Molecular weight: 23028.91 Da        Isoelectric Point: 9.4170

>NTDB_id=444236 HA035_RS06170 WP_000872873.1 1253364..1253933(+) (sigH) [Staphylococcus aureus strain 16405]
MKYDLTTQDSTIKRNNAINDKDFEKLVMDLQPLIIRRIKTFGFNHYDLEDLYQEILIRMYRSVQTFDFSGEQPFTNYVQC
LITSVKYDYLRKYLATNKRMDNLINEYRVTYPCAIKRFDVENNYLNKLAIKELICQFKYLSAFEKDVMYLMCEQYKPREI
AQLMHVKEKVIYNAIQRCKNKIKRYFKMI

Nucleotide


Download         Length: 570 bp        

>NTDB_id=444236 HA035_RS06170 WP_000872873.1 1253364..1253933(+) (sigH) [Staphylococcus aureus strain 16405]
TTGAAATACGATTTGACAACTCAAGACAGTACAATCAAACGTAACAATGCAATAAATGATAAAGACTTCGAAAAGTTAGT
AATGGATCTACAACCATTAATTATTCGACGCATCAAAACATTTGGATTTAATCATTATGATTTAGAAGACTTATATCAAG
AAATACTTATACGGATGTATAGGTCGGTCCAAACATTTGATTTTAGTGGAGAGCAGCCTTTCACAAATTATGTTCAATGT
TTAATTACGTCTGTAAAGTATGATTATTTGAGAAAATATTTAGCTACAAATAAAAGAATGGATAATTTGATTAATGAATA
TAGAGTTACGTATCCATGTGCAATAAAGCGTTTTGATGTTGAAAACAATTATTTGAATAAATTAGCAATTAAAGAGTTGA
TTTGTCAGTTTAAGTATTTGAGTGCATTTGAAAAAGATGTCATGTATTTAATGTGTGAACAATATAAGCCGAGAGAAATT
GCTCAATTGATGCATGTAAAAGAGAAAGTGATTTATAATGCCATACAACGATGTAAAAATAAAATAAAACGTTATTTCAA
AATGATTTGA

Domains

Predicted by InterproScan.

Sigma-70 region 2 (Sigma70_r2)

(26-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sigH Staphylococcus aureus N315

99.471

100

0.995
  sigH Staphylococcus aureus MW2

98.413

100

0.984