Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   IUJ37_RS01810 Genome accession   NZ_CP064387
Coordinates   396673..397329 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli O104:H4 strain PartB-EcoliO104H4-RM8376     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 391673..402329
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  IUJ37_RS01780 (IUJ37_01775) dcyD 392552..393538 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  IUJ37_RS01785 (IUJ37_01780) tcyL 393553..394221 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  IUJ37_RS01790 (IUJ37_01785) tcyN 394218..394970 (+) 753 WP_001272980.1 L-cystine ABC transporter ATP-binding protein TcyN -
  IUJ37_RS01795 (IUJ37_01790) sdiA 395200..395922 (+) 723 WP_001152713.1 transcriptional regulator SdiA -
  IUJ37_RS01800 (IUJ37_01795) yecF 395990..396214 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  IUJ37_RS01805 (IUJ37_01800) yecU 396201..396377 (-) 177 WP_000590344.1 protein YecU -
  IUJ37_RS26695 - 396415..396531 (-) 117 Protein_357 transcriptional regulator -
  IUJ37_RS01810 (IUJ37_01805) letA 396673..397329 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  IUJ37_RS01815 (IUJ37_01810) uvrC 397326..399158 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  IUJ37_RS01820 (IUJ37_01815) pgsA 399215..399763 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  IUJ37_RS01840 (IUJ37_01835) yecA 400413..401078 (+) 666 WP_000847876.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=443451 IUJ37_RS01810 WP_000611335.1 396673..397329(+) (letA) [Escherichia coli O104:H4 strain PartB-EcoliO104H4-RM8376]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=443451 IUJ37_RS01810 WP_000611335.1 396673..397329(+) (letA) [Escherichia coli O104:H4 strain PartB-EcoliO104H4-RM8376]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGATATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486