Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicX   Type   Regulator
Locus tag   HKM25_RS05750 Genome accession   NZ_CP053210
Coordinates   1150390..1151199 (-) Length   269 a.a.
NCBI ID   WP_001289493.1    Uniprot ID   Q9RCS5
Organism   Streptococcus pneumoniae strain 6A-10     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1145390..1156199
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HKM25_RS05735 (HKM25_1172) - 1147855..1149726 (-) 1872 WP_000150982.1 Eco57I restriction-modification methylase domain-containing protein -
  HKM25_RS05740 (HKM25_1173) - 1149801..1150055 (-) 255 WP_001809704.1 type II toxin-antitoxin system RelE/ParE family toxin -
  HKM25_RS05745 (HKM25_1174) - 1150057..1150299 (-) 243 WP_000208080.1 DUF6290 family protein -
  HKM25_RS05750 (HKM25_1175) vicX 1150390..1151199 (-) 810 WP_001289493.1 MBL fold metallo-hydrolase Regulator
  HKM25_RS05755 (HKM25_1176) micB 1151201..1152550 (-) 1350 WP_000886210.1 cell wall metabolism sensor histidine kinase VicK Regulator
  HKM25_RS05760 (HKM25_1177) micA 1152543..1153247 (-) 705 WP_000722076.1 response regulator YycF Regulator
  HKM25_RS05765 (HKM25_1178) mutY 1153302..1154477 (-) 1176 WP_000886147.1 A/G-specific adenine glycosylase -
  HKM25_RS11950 - 1154577..1154702 (+) 126 WP_001818232.1 hypothetical protein -

Sequence

Protein


Download         Length: 269 a.a.        Molecular weight: 29916.89 Da        Isoelectric Point: 6.1743

>NTDB_id=443439 HKM25_RS05750 WP_001289493.1 1150390..1151199(-) (vicX) [Streptococcus pneumoniae strain 6A-10]
MSEIGFKYSILASGSSGNSFYLETSKKKLLVDAGLSGKKITSLLAEINRKPEDLDAILITHEHSDHIHGVGVLARKYGMD
LYANEKTWQAMENSKYLGKVDSSQKHIFEMGKTKTFGDIDIESFGVSHDAVAPQFYRFMKDDKSFVLLTDTGYVSDRMAG
IVENADGYLIEANHDVEILRSGSYAWRLKQRILSDLGHLSNEDGAEAMIRTLGNRTKKIYLGHLSKENNIKELAHMTMVN
QLAQADLGVGVDFKVYDTSPDTATPLTEI

Nucleotide


Download         Length: 810 bp        

>NTDB_id=443439 HKM25_RS05750 WP_001289493.1 1150390..1151199(-) (vicX) [Streptococcus pneumoniae strain 6A-10]
ATGAGTGAAATAGGCTTTAAATACAGTATTTTAGCGTCGGGTTCCAGTGGAAATTCTTTTTATCTGGAAACCTCAAAAAA
GAAGCTTTTAGTAGATGCAGGCTTGTCTGGCAAGAAAATTACCAGTCTGCTAGCTGAAATTAACCGTAAGCCAGAAGACC
TGGATGCCATCTTGATTACCCATGAGCATTCAGATCATATCCATGGAGTAGGCGTTTTGGCTCGCAAGTATGGTATGGAT
CTTTATGCCAATGAAAAGACCTGGCAAGCTATGGAAAATAGTAAATATCTTGGCAAGGTGGATTCTTCGCAAAAGCATAT
TTTTGAAATGGGTAAAACCAAAACCTTTGGAGATATCGACATCGAGAGTTTTGGTGTAAGCCATGATGCAGTCGCACCGC
AGTTCTATCGCTTTATGAAGGATGATAAGAGTTTTGTCCTCTTGACAGATACAGGTTATGTCAGTGACCGTATGGCGGGC
ATTGTCGAAAATGCGGATGGTTATCTTATCGAGGCCAACCATGATGTAGAGATTTTGCGATCAGGTTCTTACGCTTGGCG
CCTCAAACAACGAATCCTATCTGACCTTGGTCACCTTTCTAACGAGGACGGTGCTGAAGCTATGATTCGGACGCTAGGAA
ATCGTACTAAGAAGATTTACCTTGGGCATTTATCTAAGGAAAATAATATCAAGGAACTGGCTCATATGACCATGGTCAAT
CAGCTGGCTCAAGCTGATCTGGGAGTCGGAGTAGACTTTAAGGTTTATGATACCTCACCAGATACCGCAACACCATTGAC
AGAGATATAG

Domains

Predicted by InterproScan.

Metallo-beta-lactamase superfamily (Lactamase_B)

(15-223)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q9RCS5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicX Streptococcus mutans UA159

77.323

100

0.773