Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   HKM25_RS01945 Genome accession   NZ_CP053210
Coordinates   366939..367628 (+) Length   229 a.a.
NCBI ID   WP_000518018.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 6A-10     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 361939..372628
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HKM25_RS01920 (HKM25_387) gpsB 362048..362377 (+) 330 WP_000146522.1 cell division regulator GpsB -
  HKM25_RS01930 (HKM25_389) - 362863..364020 (+) 1158 WP_000711402.1 class I SAM-dependent RNA methyltransferase -
  HKM25_RS01935 (HKM25_390) mapZ 364033..365427 (+) 1395 WP_000039258.1 mid-cell-anchored protein MapZ -
  HKM25_RS01940 (HKM25_391) gndA 365503..366927 (+) 1425 WP_000158783.1 NADP-dependent phosphogluconate dehydrogenase -
  HKM25_RS01945 (HKM25_392) covR 366939..367628 (+) 690 WP_000518018.1 response regulator transcription factor Regulator
  HKM25_RS01950 (HKM25_393) cbpC 367726..368691 (+) 966 WP_000771090.1 choline-binding protein CbpC -
  HKM25_RS01955 (HKM25_394) cbpJ 368710..369708 (+) 999 WP_000771122.1 choline-binding protein CbpJ -
  HKM25_RS01960 (HKM25_395) - 369826..371058 (-) 1233 WP_000765699.1 MFS transporter -
  HKM25_RS01965 - 371218..371688 (-) 471 WP_001809487.1 lanthionine synthetase LanC family protein -
  HKM25_RS01970 (HKM25_397) - 371588..371977 (-) 390 WP_196301600.1 lanthionine synthetase LanC family protein -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26898.22 Da        Isoelectric Point: 6.9836

>NTDB_id=443423 HKM25_RS01945 WP_000518018.1 366939..367628(+) (covR) [Streptococcus pneumoniae strain 6A-10]
MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQTDYDLMLLNVNLGDMMAQDFAEKLSRTKPASVIMIL
DHWEDLQEELEVVQRFAVSYIYKPVLIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=443423 HKM25_RS01945 WP_000518018.1 366939..367628(+) (covR) [Streptococcus pneumoniae strain 6A-10]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTAGCTCATTTTTTAAGTTTGGAACTCCAGAAAGAGCAGTA
TCGGGTTGATCTGGTAGAGGAGGGGCAAAAAGCCCTCTCCATGGCTCTTCAGACAGACTATGATTTGATGTTATTGAACG
TTAATCTGGGAGATATGATGGCTCAGGATTTTGCAGAAAAATTGAGTCGAACTAAACCTGCCTCAGTCATCATGATTTTA
GATCATTGGGAAGACTTGCAAGAAGAGCTGGAAGTTGTTCAGCGTTTTGCAGTTTCATACATTTATAAGCCAGTCCTTAT
CGAAAATCTGGTAGCGCGTATTTCGGCGATCTTCCGAGGTCGGGACTTCATTGATCAACACTGCAGTCTGATGAAAGTTC
CAAGGACCTACCGCAATCTTAGGATAGATGTTGAACATCACACGGTTTATCGTGGTGAAGAGATGATTGCTCTGACCCGC
CGTGAGTATGACCTTTTGGCGACACTTATGGGAAGCAAGAAAGTATTGACTCGTGAGCAATTGTTGGAAAGTGTTTGGAA
GTATGAAAGTGCGACCGAGACAAATATCGTAGATGTCTATATCCGCTATCTACGGAGCAAGCTTGATGTTAAAGGCCAAA
AAAGCTACATTAAAACCGTGCGTGGTGTTGGATATACCATGCAAGAATAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

47.826

100

0.48
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.087

100

0.463