Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   HLB22_RS07970 Genome accession   NZ_CP053101
Coordinates   1664307..1664993 (-) Length   228 a.a.
NCBI ID   WP_075583650.1    Uniprot ID   -
Organism   Staphylococcus aureus strain EDCC5398     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1659307..1669993
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HLB22_RS07950 (HLB22_07950) rpsT 1660221..1660472 (+) 252 WP_001274017.1 30S ribosomal protein S20 -
  HLB22_RS07955 (HLB22_07955) holA 1660517..1661491 (-) 975 WP_001282562.1 DNA polymerase III subunit delta -
  HLB22_RS07960 (HLB22_07960) comEC 1661548..1663749 (-) 2202 WP_001670363.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  HLB22_RS07965 (HLB22_07965) - 1663754..1664215 (-) 462 WP_000439693.1 ComE operon protein 2 -
  HLB22_RS07970 (HLB22_07970) comEA 1664307..1664993 (-) 687 WP_075583650.1 ComEA family DNA-binding protein Machinery gene
  HLB22_RS07975 (HLB22_07975) - 1665033..1665749 (-) 717 WP_000084824.1 class I SAM-dependent methyltransferase -
  HLB22_RS07980 (HLB22_07980) rsfS 1665752..1666105 (-) 354 WP_001088022.1 ribosome silencing factor -
  HLB22_RS07985 (HLB22_07985) yqeK 1666106..1666690 (-) 585 WP_001019324.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  HLB22_RS07990 (HLB22_07990) nadD 1666680..1667249 (-) 570 WP_000725167.1 nicotinate (nicotinamide) nucleotide adenylyltransferase -
  HLB22_RS07995 (HLB22_07995) yhbY 1667252..1667542 (-) 291 WP_000955235.1 ribosome assembly RNA-binding protein YhbY -
  HLB22_RS08000 (HLB22_08000) aroE 1667546..1668352 (-) 807 WP_000666749.1 shikimate dehydrogenase -
  HLB22_RS08005 (HLB22_08005) yqeH 1668366..1669466 (-) 1101 WP_001280141.1 ribosome biogenesis GTPase YqeH -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 25787.53 Da        Isoelectric Point: 9.6753

>NTDB_id=443040 HLB22_RS07970 WP_075583650.1 1664307..1664993(-) (comEA) [Staphylococcus aureus strain EDCC5398]
MVLLYQFLLRYKDFLTQWKLYIISAVVLIMVLIGFIFWRQDDYTSRNFENKDTALKQSTSENSSLSKLEDVQVKDGDNSK
NKGPVYVDVKGAVKHPNVYKMTSKDRVVDLLDKAQLLEDADVSQINLSEKLTDQKMIFIPHKGQKNVEPQIGVNSVHVKN
GNTNNTKVNLNTASVSELMSVPGVGQAKANAIVEYRNQQGAFQEIDDLKKVKGFGSKTFDKLKSYFTI

Nucleotide


Download         Length: 687 bp        

>NTDB_id=443040 HLB22_RS07970 WP_075583650.1 1664307..1664993(-) (comEA) [Staphylococcus aureus strain EDCC5398]
GTGGTTTTATTGTATCAATTTTTATTACGCTATAAAGATTTTTTAACTCAGTGGAAGTTATATATTATAAGTGCTGTTGT
TTTAATTATGGTATTAATTGGTTTTATATTCTGGAGACAAGATGATTATACTTCAAGAAATTTTGAAAATAAAGATACTG
CTCTGAAACAAAGCACTAGTGAAAATAGTAGTTTGTCCAAATTAGAAGATGTCCAGGTCAAAGATGGAGATAATTCCAAA
AATAAAGGTCCTGTATATGTCGATGTAAAAGGTGCTGTTAAACATCCTAATGTTTATAAAATGACATCTAAGGATAGAGT
AGTTGATTTACTTGATAAAGCACAATTATTGGAGGATGCAGATGTAAGTCAAATTAATTTGTCTGAAAAATTAACAGATC
AAAAAATGATTTTCATACCTCATAAAGGACAAAAGAATGTTGAACCACAAATTGGAGTAAACAGTGTGCATGTAAAAAAT
GGGAACACAAATAATACTAAAGTAAATTTAAATACCGCATCTGTATCAGAATTGATGTCTGTTCCTGGAGTAGGGCAAGC
TAAAGCTAATGCAATTGTTGAATATCGCAACCAACAAGGTGCATTTCAAGAAATTGACGATTTGAAAAAAGTAAAAGGTT
TTGGAAGTAAAACTTTTGATAAACTGAAATCTTATTTCACGATATAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(164-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Staphylococcus aureus MW2

99.123

100

0.991
  comEA Staphylococcus aureus N315

98.246

100

0.982