Detailed information    

insolico Bioinformatically predicted

Overview

Name   sigH   Type   Regulator
Locus tag   HLB22_RS02520 Genome accession   NZ_CP053101
Coordinates   550030..550599 (+) Length   189 a.a.
NCBI ID   WP_000872873.1    Uniprot ID   -
Organism   Staphylococcus aureus strain EDCC5398     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 545030..555599
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HLB22_RS02495 (HLB22_02495) cysE 546243..546890 (+) 648 WP_001805237.1 serine O-acetyltransferase -
  HLB22_RS02500 (HLB22_02500) cysS 546874..548274 (+) 1401 WP_000631963.1 cysteine--tRNA ligase -
  HLB22_RS02505 (HLB22_02505) - 548267..548671 (+) 405 WP_000370182.1 Mini-ribonuclease 3 -
  HLB22_RS02510 (HLB22_02510) rlmB 548679..549425 (+) 747 WP_000390332.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
  HLB22_RS02515 (HLB22_02515) - 549425..549949 (+) 525 WP_000664732.1 NYN domain-containing protein -
  HLB22_RS02520 (HLB22_02520) sigH 550030..550599 (+) 570 WP_000872873.1 RNA polymerase sigma factor Regulator
  HLB22_RS02525 (HLB22_02525) rpmG 550714..550857 (+) 144 WP_001788193.1 50S ribosomal protein L33 -
  HLB22_RS02530 (HLB22_02530) secE 550913..551095 (+) 183 WP_001074473.1 preprotein translocase subunit SecE -
  HLB22_RS02535 (HLB22_02535) nusG 551108..551656 (+) 549 WP_001288298.1 transcription termination/antitermination protein NusG -
  HLB22_RS02540 (HLB22_02540) rplK 551837..552259 (+) 423 WP_001085795.1 50S ribosomal protein L11 -
  HLB22_RS02545 (HLB22_02545) rplA 552467..553159 (+) 693 WP_001074619.1 50S ribosomal protein L1 -
  HLB22_RS02550 (HLB22_02550) rplJ 553431..553931 (+) 501 WP_001273087.1 50S ribosomal protein L10 -
  HLB22_RS02555 (HLB22_02555) rplL 553974..554342 (+) 369 WP_001273586.1 50S ribosomal protein L7/L12 -
  HLB22_RS02560 (HLB22_02560) - 554517..555125 (+) 609 WP_000020302.1 class I SAM-dependent methyltransferase -

Sequence

Protein


Download         Length: 189 a.a.        Molecular weight: 23028.91 Da        Isoelectric Point: 9.4170

>NTDB_id=443021 HLB22_RS02520 WP_000872873.1 550030..550599(+) (sigH) [Staphylococcus aureus strain EDCC5398]
MKYDLTTQDSTIKRNNAINDKDFEKLVMDLQPLIIRRIKTFGFNHYDLEDLYQEILIRMYRSVQTFDFSGEQPFTNYVQC
LITSVKYDYLRKYLATNKRMDNLINEYRVTYPCAIKRFDVENNYLNKLAIKELICQFKYLSAFEKDVMYLMCEQYKPREI
AQLMHVKEKVIYNAIQRCKNKIKRYFKMI

Nucleotide


Download         Length: 570 bp        

>NTDB_id=443021 HLB22_RS02520 WP_000872873.1 550030..550599(+) (sigH) [Staphylococcus aureus strain EDCC5398]
TTGAAATATGATTTGACAACTCAAGACAGTACAATCAAACGTAACAATGCAATAAATGATAAAGACTTCGAAAAGTTAGT
AATGGATCTACAACCATTAATTATTCGACGCATCAAAACATTTGGATTTAATCATTATGATTTAGAAGACTTATATCAAG
AAATACTTATACGGATGTATAGGTCGGTCCAAACATTTGATTTTAGTGGAGAGCAGCCTTTCACAAATTATGTTCAATGT
TTAATTACGTCTGTAAAGTATGATTATTTGAGAAAATATTTAGCTACAAATAAAAGAATGGATAATTTGATTAATGAATA
TAGAGTTACGTATCCATGTGCAATAAAGCGTTTTGATGTTGAAAACAATTATTTGAATAAATTAGCAATTAAAGAGTTGA
TTTGTCAGTTTAAGTATTTGAGTGCATTTGAAAAAGATGTCATGTATTTAATGTGTGAACAATATAAGCCGAGAGAAATT
GCTCAATTGATGCATGTAAAAGAGAAAGTGATTTATAATGCCATACAACGATGTAAAAATAAAATAAAACGTTATTTCAA
AATGATTTGA

Domains

Predicted by InterproScan.

Sigma-70 region 2 (Sigma70_r2)

(26-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sigH Staphylococcus aureus N315

99.471

100

0.995
  sigH Staphylococcus aureus MW2

98.413

100

0.984