Detailed information    

insolico Bioinformatically predicted

Overview

Name   comK/comK1   Type   Regulator
Locus tag   HH313_RS04820 Genome accession   NZ_CP053070
Coordinates   1015479..1016048 (-) Length   189 a.a.
NCBI ID   WP_000287265.1    Uniprot ID   A0A7U7EXU5
Organism   Staphylococcus aureus strain HL20709 isolate HL20709     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1010479..1021048
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HH313_RS04800 (HH313_000962) - 1011982..1013340 (+) 1359 WP_000021872.1 TrkH family potassium uptake protein -
  HH313_RS04805 (HH313_000963) - 1013479..1014990 (+) 1512 WP_000414178.1 bifunctional UDP-sugar hydrolase/5'-nucleotidase -
  HH313_RS04820 (HH313_000966) comK/comK1 1015479..1016048 (-) 570 WP_000287265.1 competence protein ComK Regulator
  HH313_RS04825 (HH313_000967) - 1016258..1016476 (+) 219 WP_000876826.1 IDEAL domain-containing protein -
  HH313_RS04830 (HH313_000968) - 1016557..1017543 (-) 987 WP_000668820.1 lipoate--protein ligase -
  HH313_RS04835 (HH313_000969) - 1017742..1017918 (+) 177 WP_000214898.1 YkvS family protein -
  HH313_RS04840 (HH313_000970) - 1017933..1018535 (+) 603 WP_001033867.1 CPBP family glutamic-type intramembrane protease -
  HH313_RS04845 (HH313_000971) - 1018931..1020577 (+) 1647 WP_170171870.1 IS1182-like element ISSau3 family transposase -
  HH313_RS14220 - 1020876..1020938 (+) 63 WP_228764722.1 hypothetical protein -

Sequence

Protein


Download         Length: 189 a.a.        Molecular weight: 22601.83 Da        Isoelectric Point: 9.6091

>NTDB_id=442688 HH313_RS04820 WP_000287265.1 1015479..1016048(-) (comK/comK1) [Staphylococcus aureus strain HL20709 isolate HL20709]
MYSQNIYVIRKGDMVIRPAFDDDDQRNGSEIIRFDKTRIQNPFKVQKIIERSCKFYGNTYLGKKAETNRITGISSKPPIL
LTPLFPTYFFPTHSDRQNENIWLNMHYIESIKELKNRKCKVTFINNESIILHVSYHSLWHQYNNSIFYYYMVDKQSRMIS
KNPDQPIDYNKATLNVFEALTRYSLFEDK

Nucleotide


Download         Length: 570 bp        

>NTDB_id=442688 HH313_RS04820 WP_000287265.1 1015479..1016048(-) (comK/comK1) [Staphylococcus aureus strain HL20709 isolate HL20709]
ATGTATTCTCAAAATATTTATGTGATACGCAAAGGAGACATGGTTATTCGACCAGCATTTGATGATGACGATCAAAGAAA
TGGTAGCGAAATAATTCGGTTTGACAAAACGCGTATTCAAAATCCTTTTAAAGTCCAGAAAATCATTGAACGCTCTTGCA
AATTTTATGGTAATACTTATCTTGGCAAGAAAGCAGAGACAAACCGCATCACTGGCATTTCTAGTAAACCACCTATTTTA
CTAACACCATTATTTCCAACTTATTTTTTCCCAACACATTCTGACAGACAAAATGAAAATATTTGGTTAAATATGCATTA
TATCGAAAGTATTAAAGAATTAAAAAATCGTAAATGTAAAGTGACATTTATTAATAATGAATCAATCATTCTTCATGTTT
CATACCACAGTTTATGGCATCAATATAACAATTCCATTTTTTACTATTATATGGTAGATAAACAATCTCGCATGATATCA
AAAAATCCCGACCAACCAATAGATTATAATAAAGCCACATTGAATGTGTTTGAAGCATTGACACGCTATTCTTTATTTGA
AGATAAATAA

Domains

Predicted by InterproScan.

ComK protein (ComK)

(5-156)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7EXU5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comK/comK1 Staphylococcus aureus MW2

100

100

1
  comK/comK1 Staphylococcus aureus N315

100

100

1