Detailed information NTG0441898

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: IRJ26_RS10710
• Genome accession: NZ_CP064094
• Coordinates: 2039591..2040748 (+)
• Length: 385 a.a.
• NCBI ID: WP_003227983.1
• Uniprot ID: Q3LHN6
• Organism: Bacillus subtilis strain N1108-5at
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 2034591..2045748

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
IRJ26_RS10690	tuaH	2035059..2036252 (+)	1194	WP_003243252.1	glycosyltransferase family 1 protein	-
IRJ26_RS10695	tagO	2036397..2037473 (+)	1077	WP_003227975.1	MraY family glycosyltransferase	-
IRJ26_RS10700	tagV	2037546..2038721 (-)	1176	WP_003244117.1	polyisoprenyl-teichoic acid--peptidoglycan teichoic acid transferase TagV	-
IRJ26_RS10705	yvyE	2038721..2039374 (-)	654	WP_003227979.1	YigZ family protein	-
IRJ26_RS10710	degS	2039591..2040748 (+)	1158	WP_003227983.1	two-component sensor histidine kinase DegS	Regulator
IRJ26_RS10715	degU	2040831..2041520 (+)	690	WP_003219701.1	two-component system response regulator DegU	-
IRJ26_RS10720	fakBA	2041618..2042463 (+)	846	WP_003244125.1	DegV family protein	-
IRJ26_RS10725	comFA	2042569..2043960 (+)	1392	WP_003243962.1	ATP-dependent helicase ComFA	Machinery gene
IRJ26_RS10730	comFB	2044020..2044316 (+)	297	WP_003227989.1	late competence protein ComFB	-
IRJ26_RS10735	comFC	2044280..2045002 (+)	723	WP_003227991.1	comF operon protein ComFC	Machinery gene
IRJ26_RS10740	yvyF	2045076..2045495 (+)	420	WP_003227995.1	TIGR03826 family flagellar region protein	-

Sequence

Protein

• Length: 385 a.a.
• Molecular weight: 44957.76 Da
• Isoelectric Point: 6.2957

>NTDB_id=441898 IRJ26_RS10710 WP_003227983.1 2039591..2040748(+) (degS) [Bacillus subtilis strain N1108-5at]
MNKTKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVQTRHARNRLSEVSR
NFHRFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLREVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGAEDGFQEIKNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGETEDQRLAPQFEVALFRLAQEAVSNALKHSESEEITVKVEI
TKDFVILMIKDNGKGFDLKEAKEKKNKSFGLLGMKERVDLLEGTMTIDSKIGLGTFIMIKVPLSL

Nucleotide

• Length: 1158 bp

>NTDB_id=441898 IRJ26_RS10710 WP_003227983.1 2039591..2040748(+) (degS) [Bacillus subtilis strain N1108-5at]
ATGAATAAAACAAAGATGGATTCCAAAGTGCTGGATTCTATTTTGATGAAGATGCTGAAAACCGTTGACGGGAGCAAGGA
CGAGGTTTTTCAAATCGGGGAGCAGTCACGCCAGCAGTATGAACAGCTGGTCGAAGAACTGAAACAAATTAAACAGCAGG
TGTATGAAGTGATTGAGCTTGGCGATAAACTTGAAGTGCAAACTCGCCATGCGAGAAACCGTTTATCCGAGGTCAGCCGT
AATTTTCATAGATTCAGTGAAGAGGAAATCCGCAATGCTTATGAAAAAGCCCATAAGCTGCAGGTAGAATTGACGATGAT
CCAGCAGCGTGAGAAGCAATTGCGCGAACGGCGGGACGATTTGGAGCGCAGATTGCTAGGGCTTCAGGAAATCATTGAGC
GGTCAGAATCATTAGTAAGCCAAATTACAGTTGTGCTCAACTACTTGAATCAGGATTTGCGCGAAGTTGGACTGCTTCTT
GCTGATGCTCAGGCAAAACAGGATTTCGGCTTAAGAATTATTGAGGCGCAGGAAGAAGAGCGAAAAAGAGTCTCAAGAGA
AATCCATGACGGACCCGCTCAAATGCTGGCGAATGTTATGATGAGATCGGAATTAATCGAGCGGATTTTCCGTGACCGGG
GCGCAGAGGACGGATTCCAAGAAATTAAAAATCTCCGCCAAAATGTTCGGAATGCCCTTTACGAAGTGAGAAGGATTATA
TATGATTTAAGACCGATGGCCCTTGATGACCTAGGCCTGATTCCAACTTTAAGAAAATATCTATATACAACCGAGGAATA
TAACGGGAAGGTCAAAATACATTTTCAGTGCATTGGAGAAACAGAGGATCAGAGGCTAGCGCCTCAGTTTGAGGTTGCGC
TCTTCAGGCTCGCACAGGAAGCTGTGTCTAATGCGCTAAAGCATTCTGAATCTGAAGAAATTACAGTCAAAGTTGAGATC
ACAAAGGATTTTGTGATTTTAATGATAAAAGATAACGGTAAAGGGTTCGACCTGAAGGAAGCGAAAGAGAAGAAAAACAA
ATCATTCGGCTTGCTGGGCATGAAAGAAAGAGTAGATTTATTGGAAGGAACGATGACAATAGATTCGAAAATAGGTCTTG
GGACATTTATTATGATTAAGGTTCCGTTATCTCTTTGA

Domains

Predicted by InterProScan.

• Histidine kinase (HisKA_3) (180-248)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

3D structure

• AlphaFold DB: Q3LHN6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	100	100	1