Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   IQS15_RS17615 Genome accession   NZ_CP063487
Coordinates   3679925..3681757 (+) Length   610 a.a.
NCBI ID   WP_046425971.1    Uniprot ID   -
Organism   Escherichia coli strain EF7-18-51     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 3674925..3686757
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  IQS15_RS17580 (IQS15_17590) dcyD 3675151..3676137 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  IQS15_RS17585 (IQS15_17595) tcyL 3676152..3676820 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  IQS15_RS17590 (IQS15_17600) tcyN 3676817..3677569 (+) 753 WP_001272991.1 L-cystine ABC transporter ATP-binding protein TcyN -
  IQS15_RS17595 (IQS15_17605) sdiA 3677799..3678521 (+) 723 WP_024231281.1 transcriptional regulator SdiA -
  IQS15_RS17600 (IQS15_17610) yecF 3678589..3678813 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  IQS15_RS17605 (IQS15_17615) yecU 3678800..3678976 (-) 177 WP_000590347.1 protein YecU -
  IQS15_RS17610 (IQS15_17620) letA 3679272..3679928 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  IQS15_RS17615 (IQS15_17625) uvrC 3679925..3681757 (+) 1833 WP_046425971.1 excinuclease ABC subunit UvrC Machinery gene
  IQS15_RS17620 (IQS15_17630) pgsA 3681814..3682362 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  IQS15_RS17640 (IQS15_17650) - 3683057..3683797 (-) 741 Protein_3464 hypothetical protein -
  IQS15_RS17645 (IQS15_17655) - 3683878..3685077 (+) 1200 WP_001172378.1 site-specific integrase -
  IQS15_RS17650 (IQS15_17660) - 3685183..3685350 (+) 168 WP_223717474.1 hypothetical protein -
  IQS15_RS17655 (IQS15_17665) - 3685447..3685818 (+) 372 WP_223717473.1 hypothetical protein -
  IQS15_RS17660 (IQS15_17670) - 3685844..3686377 (+) 534 WP_000045627.1 hypothetical protein -

Sequence

Protein


Download         Length: 610 a.a.        Molecular weight: 68216.09 Da        Isoelectric Point: 9.3685

>NTDB_id=440094 IQS15_RS17615 WP_046425971.1 3679925..3681757(+) (uvrC) [Escherichia coli strain EF7-18-51]
MSDQFDAKAFLKTVTSQPGVYRMYDAGGTVIYVGKAKDLKKRLSSYFRSNLASRKTEALVAQIQQIDVTVTHTETEALLL
EHNYIKLYQPRYNVLLRDDKSYPFIFLSGDTHPRLAMHRGAKHAKGEYFGPFPNGYAVRETLALLQKIFPIRQCENSVYR
NRSRPCLQYQIGRCLGPCVEGLVSEEEYAQQVEYVRLFLSGKDDQVLTQLISRMETASQNLEFEEAARIRDQIQAVRRVT
EKQFVSNTGDDLDVIGVAFDVGMACVHVLFIRQGKVLGSRSYFPKVPGGTELSEVVETFVGQFYLQGSQMRTLPGEILLD
FNLSDKTLLADSLSELAGRKINVQTKPRGDRARYLKLARTNAATALTSKLSQQSTVHQRLTALASVLKLPEVKRMECFDI
SHTMGEQTVASCVVFDANGPLRAEYRRYNITGITPGDDYAAMNQVLRRRYGKAIDDSKIPDVILIDGGKGQLAQAKNVFA
ELDVSWDKNHPLLLGVAKGADRKAGLETLFFEPEGEGFSLPPDSPALHVIQHIRDESHDHAIGGHRKKRAKVKNTSSLET
IEGVGPKRRQMLLKYMGGLQGLRNASVEEIAKVPGISQGLAEKIFWSLKH

Nucleotide


Download         Length: 1833 bp        

>NTDB_id=440094 IQS15_RS17615 WP_046425971.1 3679925..3681757(+) (uvrC) [Escherichia coli strain EF7-18-51]
GTGAGTGATCAGTTTGACGCAAAAGCGTTTTTAAAAACCGTAACCAGCCAGCCTGGCGTTTATCGCATGTACGATGCTGG
TGGTACGGTTATCTATGTCGGCAAAGCGAAAGACCTGAAAAAACGGCTTTCCAGCTATTTCCGTAGCAACCTCGCTTCGC
GCAAAACCGAAGCGCTGGTCGCCCAGATCCAGCAAATTGATGTAACGGTTACTCATACAGAAACCGAAGCGCTGTTGCTG
GAACACAACTACATCAAACTCTATCAGCCGCGTTACAACGTTTTACTACGCGATGATAAATCATATCCTTTTATCTTCCT
GAGTGGCGATACCCATCCGCGTCTGGCGATGCATCGTGGTGCGAAGCATGCCAAAGGTGAATATTTCGGCCCGTTCCCGA
ATGGCTATGCCGTACGTGAAACACTGGCGCTACTGCAAAAGATTTTCCCCATTCGCCAGTGCGAAAACAGTGTTTATCGC
AATCGCTCGCGTCCGTGTCTGCAATATCAGATAGGACGTTGTCTGGGGCCGTGCGTTGAAGGACTGGTGAGTGAAGAAGA
ATACGCTCAGCAGGTCGAGTATGTGCGCCTGTTTTTGTCTGGCAAAGATGATCAGGTGCTTACGCAACTGATTAGCCGTA
TGGAAACTGCCAGCCAGAATCTGGAGTTTGAAGAAGCGGCACGTATTCGCGACCAAATTCAGGCGGTGCGACGCGTCACC
GAAAAACAGTTTGTGTCCAATACCGGCGACGACCTCGACGTTATTGGTGTGGCGTTCGATGTGGGCATGGCTTGTGTCCA
CGTATTGTTCATTCGTCAGGGCAAAGTGCTTGGCAGCCGCAGCTATTTCCCGAAAGTGCCTGGCGGTACGGAACTGAGCG
AGGTGGTGGAAACCTTCGTAGGACAGTTCTATTTACAAGGCAGCCAGATGCGCACCTTACCGGGTGAGATCCTGCTCGAT
TTTAATCTTAGCGATAAAACGCTGCTCGCCGATTCCCTTTCAGAACTGGCGGGACGCAAGATTAATGTTCAAACCAAACC
TCGTGGCGATAGGGCGCGTTACCTGAAACTCGCGCGCACCAATGCGGCGACGGCCTTAACCAGCAAACTTTCGCAGCAAT
CTACCGTTCACCAGCGGCTTACAGCACTTGCCAGCGTGTTGAAATTGCCGGAAGTGAAGCGGATGGAGTGCTTTGACATC
AGCCATACCATGGGTGAACAAACCGTCGCTTCCTGTGTGGTGTTTGATGCTAACGGCCCGCTGCGTGCGGAGTATCGGCG
CTATAACATTACTGGCATCACGCCGGGCGATGATTATGCGGCGATGAATCAGGTGCTGCGTCGGCGTTATGGTAAAGCCA
TCGACGACAGTAAGATCCCGGATGTGATACTTATCGACGGCGGCAAAGGCCAGCTTGCGCAGGCGAAAAATGTCTTCGCC
GAACTGGATGTCTCATGGGATAAAAATCATCCGCTGCTACTTGGCGTTGCCAAAGGAGCAGATCGTAAGGCTGGGCTGGA
AACGCTGTTCTTTGAGCCGGAAGGTGAGGGATTCAGTTTGCCGCCAGATTCTCCCGCGCTGCATGTTATCCAGCATATTC
GCGATGAATCACATGATCACGCGATTGGCGGGCACCGTAAAAAACGGGCGAAGGTCAAAAATACCAGTTCCCTGGAAACC
ATTGAAGGCGTCGGGCCAAAACGCCGGCAAATGTTGTTGAAATATATGGGTGGTTTGCAAGGTTTACGTAACGCCAGCGT
CGAGGAAATTGCAAAAGTGCCGGGTATTTCGCAAGGTCTGGCAGAAAAGATCTTCTGGTCGTTGAAACATTGA

Domains

Predicted by InterProScan.

UvrB/uvrC motif (UVR)

(205-237)

Helix-hairpin-helix domain (HHH_5)

(558-609)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-542)

GIY-YIG catalytic domain (GIY-YIG)

(18-93)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae TIGR4

37.891

99.508

0.377
  uvrC Streptococcus pneumoniae R6

37.562

99.508

0.374
  uvrC Streptococcus pneumoniae D39

37.562

99.508

0.374