Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   IQS22_RS16550 Genome accession   NZ_CP063479
Coordinates   3441821..3442477 (-) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain EM06-18-14     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 3436821..3447477
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  IQS22_RS16520 (IQS22_16530) - 3437951..3438691 (+) 741 Protein_3261 hypothetical protein -
  IQS22_RS16540 (IQS22_16550) pgsA 3439387..3439935 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  IQS22_RS16545 (IQS22_16555) uvrC 3439992..3441824 (-) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  IQS22_RS16550 (IQS22_16560) letA 3441821..3442477 (-) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  IQS22_RS24685 - 3442619..3442690 (+) 72 Protein_3265 transcriptional regulator -
  IQS22_RS16555 (IQS22_16565) yecU 3442773..3442949 (+) 177 WP_000590347.1 protein YecU -
  IQS22_RS16560 (IQS22_16570) yecF 3442936..3443160 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  IQS22_RS16565 (IQS22_16575) sdiA 3443227..3443949 (-) 723 WP_001154271.1 transcriptional regulator SdiA -
  IQS22_RS16570 (IQS22_16580) tcyN 3444179..3444931 (-) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  IQS22_RS16575 (IQS22_16585) tcyL 3444928..3445596 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  IQS22_RS16580 (IQS22_16590) dcyD 3445611..3446597 (-) 987 WP_001128215.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=439918 IQS22_RS16550 WP_000611335.1 3441821..3442477(-) (letA) [Escherichia coli strain EM06-18-14]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=439918 IQS22_RS16550 WP_000611335.1 3441821..3442477(-) (letA) [Escherichia coli strain EM06-18-14]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTTGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486