Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   HHM65_RS04610 Genome accession   NZ_CP051624
Coordinates   892900..894129 (+) Length   409 a.a.
NCBI ID   WP_003054192.1    Uniprot ID   -
Organism   Streptococcus dysgalactiae subsp. equisimilis strain TPCH-A74     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 887900..899129
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HHM65_RS04585 (HHM65_04590) - 888522..889799 (-) 1278 WP_015057516.1 hydroxymethylglutaryl-CoA reductase, degradative -
  HHM65_RS04590 (HHM65_04595) - 889780..890961 (-) 1182 WP_015057517.1 hydroxymethylglutaryl-CoA synthase -
  HHM65_RS04595 (HHM65_04600) - 891179..892018 (+) 840 WP_003054196.1 thymidylate synthase -
  HHM65_RS04600 (HHM65_04605) - 892099..892596 (+) 498 WP_003054187.1 dihydrofolate reductase -
  HHM65_RS04605 (HHM65_04610) - 892616..892786 (+) 171 WP_003054200.1 hypothetical protein -
  HHM65_RS04610 (HHM65_04615) clpX 892900..894129 (+) 1230 WP_003054192.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  HHM65_RS04615 (HHM65_04620) yihA 894139..894738 (+) 600 WP_003061604.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  HHM65_RS04620 (HHM65_04625) - 894882..895625 (+) 744 WP_012766851.1 hypothetical protein -
  HHM65_RS04625 (HHM65_04630) clpC 895682..897781 (-) 2100 WP_015057518.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  HHM65_RS04630 (HHM65_04635) - 898054..898917 (-) 864 WP_003059989.1 IS982 family transposase -

Sequence

Protein


Download         Length: 409 a.a.        Molecular weight: 45060.54 Da        Isoelectric Point: 4.5866

>NTDB_id=439898 HHM65_RS04610 WP_003054192.1 892900..894129(+) (clpX) [Streptococcus dysgalactiae subsp. equisimilis strain TPCH-A74]
MAGNRTNDIKVYCSFCGKSQDEVKKIIAGNNVFICNECVALSQEIIKEELAEEVLADLTEVPKPKELLEVLNQYVVGQDR
AKRALSVAVYNHYKRVSFTESRDDEDVELQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENI
LLKLIQAADYNVERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQIDTK
NILFIVGGAFDGIEDIVKQRLGEKVIGFGQNSRKIDDNASYMQEIISEDIQKFGLIPEFIGRLPVVAALEQLNTSDLIQI
LTEPRNALVKQYQALLSYDGVELAFDKEALEAIANKAIERKTGARGLRSIIEETMLDIMFEIPSQEDVTKVRITKAAVEG
KSKPVLETA

Nucleotide


Download         Length: 1230 bp        

>NTDB_id=439898 HHM65_RS04610 WP_003054192.1 892900..894129(+) (clpX) [Streptococcus dysgalactiae subsp. equisimilis strain TPCH-A74]
ATGGCAGGAAATCGTACAAACGATATTAAAGTATATTGCTCATTTTGTGGTAAGAGCCAAGACGAAGTCAAAAAAATTAT
TGCAGGGAATAATGTTTTTATCTGTAATGAATGTGTGGCTTTGTCACAAGAAATTATTAAAGAAGAGTTGGCAGAAGAAG
TGTTAGCTGACCTAACAGAAGTTCCAAAACCAAAAGAACTCCTTGAGGTTTTAAACCAGTATGTTGTTGGTCAAGATCGT
GCCAAACGTGCTTTATCAGTAGCTGTTTACAATCATTACAAACGCGTGTCATTCACGGAAAGTCGTGATGATGAAGATGT
TGAATTGCAAAAATCAAACATTTTAATGATTGGTCCAACAGGTTCAGGAAAGACTTTTCTCGCTCAAACCTTAGCTAAGA
GCTTAAATGTTCCTTTTGCGATTGCTGATGCAACCTCACTGACTGAAGCAGGGTATGTTGGAGAAGATGTGGAAAATATT
CTTCTCAAGCTTATCCAAGCAGCTGATTATAATGTGGAACGAGCAGAGCGTGGTATCATCTATGTCGATGAAATTGATAA
GATTGCTAAAAAAGGTGAAAATGTGTCCATCACACGTGATGTTTCTGGTGAGGGAGTTCAACAGGCCTTGCTAAAAATCA
TTGAAGGAACGGTTGCTAGTGTTCCTCCTCAAGGCGGTCGTAAGCATCCAAATCAGGAAATGATTCAAATTGATACCAAG
AATATCTTGTTTATTGTTGGGGGAGCCTTTGATGGCATTGAAGACATTGTCAAACAACGTTTAGGAGAAAAAGTCATTGG
TTTTGGTCAAAACAGCCGAAAAATCGATGACAATGCTTCTTATATGCAAGAGATTATTTCAGAAGATATCCAAAAATTTG
GTCTTATCCCAGAGTTTATTGGACGCTTGCCAGTCGTAGCTGCTCTTGAACAACTAAACACATCAGATTTGATTCAAATT
TTGACGGAACCAAGAAATGCCCTAGTCAAGCAATATCAGGCTCTTCTTTCTTACGATGGTGTCGAATTGGCATTTGATAA
GGAAGCCTTAGAAGCCATTGCAAATAAAGCCATTGAGCGTAAGACAGGCGCGCGTGGTCTTCGTTCTATTATCGAAGAAA
CGATGTTAGACATTATGTTTGAAATTCCAAGCCAAGAAGATGTCACAAAAGTGCGTATCACCAAGGCTGCTGTCGAAGGC
AAGTCAAAACCCGTTTTAGAGACAGCTTAA

Domains

Predicted by InterproScan.

AAA domain (Cdc48 subfamily) (AAA_2)

(110-305)

ClpX C4-type zinc finger (zf-C4_ClpX)

(12-48)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(312-391)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

89.487

100

0.895
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

58.853

98.044

0.577