Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   IQS24_RS13015 Genome accession   NZ_CP063473
Coordinates   2659804..2660460 (-) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain EM18-18-42     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2654804..2665460
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  IQS24_RS12985 (IQS24_12990) yecA 2656056..2656721 (-) 666 WP_000847880.1 UPF0149 family protein YecA -
  IQS24_RS13005 (IQS24_13010) pgsA 2657370..2657918 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  IQS24_RS13010 (IQS24_13015) uvrC 2657975..2659807 (-) 1833 WP_001283424.1 excinuclease ABC subunit UvrC Machinery gene
  IQS24_RS13015 (IQS24_13020) letA 2659804..2660460 (-) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  IQS24_RS24685 - 2660602..2660718 (+) 117 WP_001302039.1 hypothetical protein -
  IQS24_RS13020 (IQS24_13025) yecU 2660756..2660932 (+) 177 WP_205595407.1 protein YecU -
  IQS24_RS13025 (IQS24_13030) yecF 2660919..2661143 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  IQS24_RS13030 (IQS24_13035) sdiA 2661211..2661933 (-) 723 WP_001154273.1 transcriptional regulator SdiA -
  IQS24_RS13035 (IQS24_13040) tcyN 2662163..2662915 (-) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  IQS24_RS13040 (IQS24_13045) tcyL 2662912..2663580 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  IQS24_RS13045 (IQS24_13050) dcyD 2663595..2664581 (-) 987 WP_001128215.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=439736 IQS24_RS13015 WP_000611328.1 2659804..2660460(-) (letA) [Escherichia coli strain EM18-18-42]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=439736 IQS24_RS13015 WP_000611328.1 2659804..2660460(-) (letA) [Escherichia coli strain EM18-18-42]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGTCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482