Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB8   Type   Machinery gene
Locus tag   HG561_RS00200 Genome accession   NZ_CP051506
Coordinates   33752..34495 (+) Length   247 a.a.
NCBI ID   WP_000660502.1    Uniprot ID   A0A0E0WAE9
Organism   Helicobacter pylori strain SHIM-007     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 28752..39495
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HG561_RS00175 (HG561_00175) panD 30893..31243 (+) 351 WP_000142282.1 aspartate 1-decarboxylase -
  HG561_RS00180 (HG561_00180) - 31254..31556 (+) 303 WP_000347918.1 YbaB/EbfC family nucleoid-associated protein -
  HG561_RS00185 (HG561_00185) - 31556..32563 (+) 1008 WP_202168857.1 PDZ domain-containing protein -
  HG561_RS00190 (HG561_00190) comB6 32571..33626 (+) 1056 WP_000786690.1 P-type conjugative transfer protein TrbL Machinery gene
  HG561_RS00195 (HG561_00195) comB7 33642..33755 (+) 114 WP_001217864.1 hypothetical protein Machinery gene
  HG561_RS00200 (HG561_00200) comB8 33752..34495 (+) 744 WP_000660502.1 virB8 family protein Machinery gene
  HG561_RS00205 (HG561_00205) comB9 34495..35451 (+) 957 WP_202168488.1 TrbG/VirB9 family P-type conjugative transfer protein Machinery gene
  HG561_RS00210 (HG561_00210) comB10 35444..36580 (+) 1137 WP_202168489.1 DNA type IV secretion system protein ComB10 Machinery gene
  HG561_RS00215 (HG561_00215) - 36650..38062 (+) 1413 WP_000694822.1 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase -
  HG561_RS00220 (HG561_00220) gmd 38077..39222 (+) 1146 WP_000659885.1 GDP-mannose 4,6-dehydratase -

Sequence

Protein


Download         Length: 247 a.a.        Molecular weight: 28599.81 Da        Isoelectric Point: 8.9830

>NTDB_id=439305 HG561_RS00200 WP_000660502.1 33752..34495(+) (comB8) [Helicobacter pylori strain SHIM-007]
MKEKPFNSEQLAFLEELLSHQEKHLENKLSGFSVSDLDMQSVFRLERNRLKIAYKLLGLMSFIALILAIVLISVLPLQKT
EHHFVDFLNQDKHYAIIQRADKSISSNEALARSLIGAYVLNRESINRIDDKSRYELVRLQSSSKVWQRFEDLIKTQNSIY
AQSHLEREVHIVNIAIYQQDNNPIASVSIAAKLMNENKLVYEKRYKIALSYLFDTPDFDYASMPKNPTGFKITRYSITEI
APTNRGD

Nucleotide


Download         Length: 744 bp        

>NTDB_id=439305 HG561_RS00200 WP_000660502.1 33752..34495(+) (comB8) [Helicobacter pylori strain SHIM-007]
ATGAAAGAAAAGCCTTTCAATAGCGAGCAGTTGGCTTTTTTAGAAGAGCTTTTAAGCCACCAAGAAAAGCATTTAGAAAA
CAAGCTTTCTGGTTTTTCGGTGAGTGATTTGGACATGCAAAGCGTGTTCAGATTAGAGAGGAACCGCTTGAAAATCGCTT
ATAAACTCTTAGGTTTGATGAGTTTTATCGCTCTTATCTTGGCGATCGTGTTAATCAGTGTTTTACCCCTACAAAAAACC
GAACACCATTTCGTGGATTTTTTAAACCAGGACAAGCATTACGCCATTATCCAAAGAGCGGATAAAAGCATTTCTAGTAA
TGAAGCGTTGGCTCGTTCGCTCATTGGGGCGTATGTGTTAAACAGGGAGAGCATTAATCGCATTGACGATAAATCGCGCT
ATGAATTGGTGCGCTTGCAAAGCAGTTCTAAAGTGTGGCAACGCTTTGAAGATTTGATTAAAACCCAAAACAGCATTTAT
GCGCAAAGCCATCTGGAAAGAGAAGTCCATATCGTCAATATTGCGATCTACCAGCAAGACAATAACCCCATTGCGAGCGT
TTCTATTGCAGCTAAACTCATGAATGAAAACAAGCTAGTTTATGAAAAGCGTTATAAAATCGCGCTGAGTTATTTGTTTG
ACACCCCGGATTTTGATTACGCTTCTATGCCCAAAAACCCTACCGGCTTTAAAATCACTCGCTACAGCATCACTGAAATC
GCGCCGACTAATAGGGGCGATTGA

Domains

Predicted by InterproScan.

VirB8 protein (VirB8)

(38-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0E0WAE9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB8 Helicobacter pylori P1

97.166

100

0.972