Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   IPV39_RS12140 Genome accession   NZ_CP063395
Coordinates   2563496..2564167 (+) Length   223 a.a.
NCBI ID   WP_023086109.1    Uniprot ID   -
Organism   Pseudomonas aeruginosa strain ST167_d57blood     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2558496..2569167
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  IPV39_RS12105 (IPV39_12110) ppyR 2558969..2559226 (+) 258 WP_023086108.1 psl/pyoverdine operon transcriptional regulator PpyR -
  IPV39_RS12110 (IPV39_12115) - 2559213..2560406 (+) 1194 WP_003122598.1 NnrS family protein -
  IPV39_RS12115 (IPV39_12120) - 2560407..2560673 (-) 267 WP_003115326.1 DUF5329 domain-containing protein -
  IPV39_RS12120 (IPV39_12125) - 2560657..2561550 (-) 894 WP_003115327.1 hypothetical protein -
  IPV39_RS12125 (IPV39_12130) - 2561577..2562659 (-) 1083 WP_003113385.1 hypothetical protein -
  IPV39_RS12130 (IPV39_12135) - 2562874..2563182 (+) 309 WP_003090497.1 PepSY domain-containing protein -
  IPV39_RS12135 (IPV39_12140) - 2563182..2563496 (+) 315 WP_003097704.1 PepSY domain-containing protein -
  IPV39_RS12140 (IPV39_12145) ciaR 2563496..2564167 (+) 672 WP_023086109.1 two-component system response regulator CarR Regulator
  IPV39_RS12145 (IPV39_12150) carS 2564164..2565501 (+) 1338 WP_003090493.1 two-component system sensor histidine kinase CarS -
  IPV39_RS12150 (IPV39_12155) - 2565592..2565900 (+) 309 WP_003113384.1 hypothetical protein -
  IPV39_RS12155 (IPV39_12160) - 2565905..2568049 (-) 2145 WP_003113383.1 methyl-accepting chemotaxis protein -

Sequence

Protein


Download         Length: 223 a.a.        Molecular weight: 24787.23 Da        Isoelectric Point: 5.5825

>NTDB_id=439233 IPV39_RS12140 WP_023086109.1 2563496..2564167(+) (ciaR) [Pseudomonas aeruginosa strain ST167_d57blood]
MRLLLVEDHVPLADELMASLTRQGYAVDWLADGRDAAVQGASEPYDLIILDLGLPGRPGLEILQEWRGLGLATPVLILTA
RDSWAERIDGLKAGADDYLTKPFHPEELALRIQALLRRAHGLANQSQLEAAGLRLDEQRQCVCLNGADVDLTAAEFRLLR
YFMLHPGQVLSKGHLAEHLYDGETERDSNVIEVHVNHLRRKLGREVIETRRGQGYRYAGVAAG

Nucleotide


Download         Length: 672 bp        

>NTDB_id=439233 IPV39_RS12140 WP_023086109.1 2563496..2564167(+) (ciaR) [Pseudomonas aeruginosa strain ST167_d57blood]
ATGCGGTTGCTGCTGGTTGAGGATCACGTTCCCCTGGCCGACGAACTGATGGCCAGCCTGACCCGCCAGGGCTACGCGGT
GGACTGGCTGGCCGACGGCCGCGACGCGGCGGTGCAGGGCGCCAGCGAACCCTACGACCTGATCATCCTCGACCTCGGCC
TGCCCGGGCGTCCCGGCCTGGAGATACTCCAGGAGTGGCGTGGGCTGGGACTCGCGACTCCGGTGCTGATCCTCACCGCG
CGCGATTCCTGGGCCGAACGCATCGATGGGCTCAAGGCCGGTGCCGACGACTACCTGACCAAGCCGTTCCATCCGGAAGA
GCTGGCCTTGCGCATCCAGGCCCTGTTGCGCCGCGCCCATGGGCTGGCCAACCAGAGCCAGCTGGAGGCCGCCGGGCTGC
GCCTGGACGAGCAGCGCCAGTGCGTGTGCCTGAACGGCGCCGACGTCGACCTGACCGCCGCCGAATTCCGCCTGCTGCGC
TATTTCATGCTGCACCCCGGCCAGGTCCTGTCCAAGGGGCACCTGGCCGAGCATCTGTACGACGGCGAGACCGAACGCGA
TTCCAACGTCATCGAGGTCCACGTCAACCACCTGCGGCGCAAGCTCGGCCGCGAGGTGATCGAGACCCGCCGTGGCCAGG
GCTACCGCTACGCCGGGGTGGCCGCCGGATGA

Domains

Predicted by InterProScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(147-216)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus mutans UA159

37.727

98.655

0.372
  ciaR Streptococcus pneumoniae Rx1

37.273

98.655

0.368
  ciaR Streptococcus pneumoniae D39

37.273

98.655

0.368
  ciaR Streptococcus pneumoniae TIGR4

37.273

98.655

0.368
  ciaR Streptococcus pneumoniae R6

37.273

98.655

0.368
  vicR Streptococcus mutans UA159

35.965

100

0.368
  micA Streptococcus pneumoniae Cp1015

36.123

100

0.368