Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB8   Type   Machinery gene
Locus tag   HG570_RS00200 Genome accession   NZ_CP051497
Coordinates   33515..34258 (+) Length   247 a.a.
NCBI ID   WP_000660502.1    Uniprot ID   A0A0E0WAE9
Organism   Helicobacter pylori strain PUNO-007     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 28515..39258
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HG570_RS00175 (HG570_00175) panD 30667..31017 (+) 351 WP_202141747.1 aspartate 1-decarboxylase -
  HG570_RS00180 (HG570_00180) - 31028..31321 (+) 294 WP_000347917.1 YbaB/EbfC family nucleoid-associated protein -
  HG570_RS00185 (HG570_00185) - 31321..32328 (+) 1008 WP_202142471.1 PDZ domain-containing protein -
  HG570_RS00190 (HG570_00190) comB6 32334..33389 (+) 1056 WP_202141748.1 P-type conjugative transfer protein TrbL Machinery gene
  HG570_RS00195 (HG570_00195) comB7 33405..33518 (+) 114 WP_001217868.1 hypothetical protein Machinery gene
  HG570_RS00200 (HG570_00200) comB8 33515..34258 (+) 744 WP_000660502.1 virB8 family protein Machinery gene
  HG570_RS00205 (HG570_00205) comB9 34258..35220 (+) 963 WP_202141749.1 TrbG/VirB9 family P-type conjugative transfer protein Machinery gene
  HG570_RS00210 (HG570_00210) comB10 35213..36349 (+) 1137 WP_202141750.1 DNA type IV secretion system protein ComB10 Machinery gene
  HG570_RS00215 (HG570_00215) - 36419..37831 (+) 1413 WP_202141751.1 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase -
  HG570_RS00220 (HG570_00220) gmd 37846..38991 (+) 1146 WP_202141752.1 GDP-mannose 4,6-dehydratase -

Sequence

Protein


Download         Length: 247 a.a.        Molecular weight: 28599.81 Da        Isoelectric Point: 8.9830

>NTDB_id=439114 HG570_RS00200 WP_000660502.1 33515..34258(+) (comB8) [Helicobacter pylori strain PUNO-007]
MKEKPFNSEQLAFLEELLSHQEKHLENKLSGFSVSDLDMQSVFRLERNRLKIAYKLLGLMSFIALILAIVLISVLPLQKT
EHHFVDFLNQDKHYAIIQRADKSISSNEALARSLIGAYVLNRESINRIDDKSRYELVRLQSSSKVWQRFEDLIKTQNSIY
AQSHLEREVHIVNIAIYQQDNNPIASVSIAAKLMNENKLVYEKRYKIALSYLFDTPDFDYASMPKNPTGFKITRYSITEI
APTNRGD

Nucleotide


Download         Length: 744 bp        

>NTDB_id=439114 HG570_RS00200 WP_000660502.1 33515..34258(+) (comB8) [Helicobacter pylori strain PUNO-007]
ATGAAAGAAAAGCCTTTCAATAGCGAGCAGTTGGCTTTTTTAGAAGAGCTTTTAAGCCACCAAGAAAAGCATTTAGAAAA
CAAGCTTTCTGGTTTTTCGGTGAGTGATTTGGACATGCAAAGCGTGTTCAGACTGGAGAGGAACCGCTTGAAAATCGCTT
ATAAACTCTTAGGCTTGATGAGTTTTATCGCTCTTATTTTAGCGATCGTGTTAATCAGTGTTCTACCCTTACAAAAAACC
GAACACCATTTCGTGGATTTTTTAAACCAGGACAAGCATTACGCCATTATCCAAAGAGCGGATAAAAGCATTTCCAGTAA
TGAAGCGTTGGCTCGTTCGCTCATTGGGGCGTATGTGTTAAACCGAGAGAGCATTAACCGCATTGACGATAAATCGCGCT
ATGAATTGGTGCGCTTGCAAAGCAGTTCTAAAGTGTGGCAACGCTTTGAAGATTTGATTAAAACGCAAAACAGCATTTAT
GCACAAAGCCATTTGGAAAGAGAAGTCCATATCGTCAATATTGCGATCTACCAGCAAGACAATAACCCCATTGCGAGCGT
TTCTATTGCAGCTAAACTCATGAATGAAAACAAACTGGTGTATGAAAAGCGTTATAAAATCGCGCTGAGTTATTTGTTTG
ACACCCCGGATTTTGATTACGCTTCCATGCCCAAAAACCCTACCGGTTTTAAAATCACTCGCTACAGCATCACTGAAATC
GCGCCGACTAATAGGGGCGATTGA

Domains

Predicted by InterproScan.

VirB8 protein (VirB8)

(38-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0E0WAE9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB8 Helicobacter pylori P1

97.166

100

0.972