Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGA   Type   Machinery gene
Locus tag   HGO93_RS02375 Genome accession   NZ_CP051482
Coordinates   446322..447296 (+) Length   324 a.a.
NCBI ID   WP_000697220.1    Uniprot ID   W8U5L8
Organism   Staphylococcus aureus strain NGA104a     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 441322..452296
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HGO93_RS02340 (HGO93_08000) rpmG 441782..441931 (+) 150 WP_001265709.1 50S ribosomal protein L33 -
  HGO93_RS02345 (HGO93_07995) - 442140..442679 (+) 540 WP_000164546.1 5-formyltetrahydrofolate cyclo-ligase -
  HGO93_RS02350 (HGO93_07990) - 442691..444154 (+) 1464 WP_001017865.1 rhomboid family intramembrane serine protease -
  HGO93_RS02355 (HGO93_07985) - 444135..444338 (+) 204 WP_000087561.1 YqgQ family protein -
  HGO93_RS02360 (HGO93_07980) - 444335..445321 (+) 987 WP_000161314.1 ROK family glucokinase -
  HGO93_RS02365 (HGO93_07975) - 445321..445650 (+) 330 WP_001018871.1 MTH1187 family thiamine-binding protein -
  HGO93_RS02370 (HGO93_07970) - 445647..446270 (+) 624 WP_001223010.1 MBL fold metallo-hydrolase -
  HGO93_RS02375 (HGO93_07965) comGA 446322..447296 (+) 975 WP_000697220.1 competence type IV pilus ATPase ComGA Machinery gene
  HGO93_RS02380 (HGO93_07960) comGB 447268..448338 (+) 1071 WP_000776422.1 competence type IV pilus assembly protein ComGB Machinery gene
  HGO93_RS02385 (HGO93_07955) comGC 448352..448663 (+) 312 WP_000472256.1 competence type IV pilus major pilin ComGC Machinery gene
  HGO93_RS02390 (HGO93_07950) comGD 448641..449087 (+) 447 WP_001788899.1 competence type IV pilus minor pilin ComGD Machinery gene
  HGO93_RS02395 (HGO93_07945) comGE 449074..449373 (+) 300 WP_000844413.1 hypothetical protein Machinery gene
  HGO93_RS02400 (HGO93_07940) comGF 449291..449788 (+) 498 WP_078368986.1 competence type IV pilus minor pilin ComGF Machinery gene
  HGO93_RS02405 (HGO93_07935) - 449885..450031 (+) 147 WP_001789879.1 hypothetical protein -
  HGO93_RS02410 (HGO93_07930) - 450021..450545 (+) 525 WP_001015121.1 shikimate kinase -
  HGO93_RS02415 (HGO93_07925) gcvT 450704..451795 (+) 1092 WP_000093349.1 glycine cleavage system aminomethyltransferase GcvT -

Sequence

Protein


Download         Length: 324 a.a.        Molecular weight: 36897.96 Da        Isoelectric Point: 8.8516

>NTDB_id=438822 HGO93_RS02375 WP_000697220.1 446322..447296(+) (comGA) [Staphylococcus aureus strain NGA104a]
MKILFQEIINKAIEMKASDVHFIPVKNEVSIKFRINDNLEQYEQIGNSIYQKLLVYMKFQAGLDVSTQQVAQSGRYSYHF
NKIYFLRISTLPLSLGQESCVIRIVPQFFQQQKSTYKFNDFKHLMNKKQGLLLFSGPTGSGKSTLMYQMVSYANKALNLN
VISIEDPVEMQIPGIVQINVNDKAGINYVNSFKAILRCDPDVILIGEIRDKDVAKCVIQASLSGHLVLTTLHATDCKGAI
LRLLEMGISVQELIQATNLIINQRLVTTIKQQRQLVCEILSQQQLRYFFSHNHSLPSSFKNLEDKLDDMTKAGVICETTM
DKYI

Nucleotide


Download         Length: 975 bp        

>NTDB_id=438822 HGO93_RS02375 WP_000697220.1 446322..447296(+) (comGA) [Staphylococcus aureus strain NGA104a]
TTGAAGATTCTATTTCAAGAAATAATTAATAAAGCGATAGAAATGAAAGCGAGTGATGTACATTTTATTCCAGTTAAAAA
TGAAGTAAGTATTAAATTTAGAATTAATGATAACTTGGAGCAGTATGAACAAATTGGGAATAGCATTTATCAAAAGTTAT
TAGTTTATATGAAGTTTCAAGCTGGGCTTGATGTTTCTACACAGCAAGTCGCACAGAGCGGTCGATATAGTTACCATTTC
AATAAAATATATTTTTTGAGAATATCAACTTTACCATTGTCACTTGGCCAAGAAAGTTGTGTTATCAGAATTGTACCTCA
ATTTTTTCAACAACAAAAATCAACTTATAAATTCAATGATTTTAAACACCTCATGAATAAGAAACAAGGATTACTATTGT
TTAGTGGGCCAACTGGTTCAGGAAAGAGTACATTAATGTATCAAATGGTCTCATACGCGAATAAAGCCTTGAATTTAAAT
GTAATTTCTATAGAGGATCCTGTAGAGATGCAAATTCCTGGTATCGTCCAAATTAATGTGAATGATAAAGCTGGCATTAA
CTATGTAAATTCGTTTAAAGCTATTTTAAGATGTGATCCTGATGTTATTTTAATAGGTGAAATCAGAGATAAAGATGTTG
CCAAGTGTGTTATACAGGCTAGTTTAAGTGGTCACCTTGTTCTGACTACATTGCATGCAACTGATTGTAAAGGTGCTATT
TTAAGGCTATTAGAAATGGGCATTTCTGTACAAGAATTGATACAGGCAACTAACTTAATTATAAACCAACGACTTGTAAC
TACTATTAAGCAACAGCGACAATTAGTATGCGAAATTCTATCTCAGCAACAACTCCGATATTTCTTTTCCCATAATCATT
CATTACCATCATCATTTAAGAACTTAGAAGATAAACTTGATGATATGACAAAAGCAGGTGTCATTTGTGAAACTACAATG
GATAAATACATTTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(7-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB W8U5L8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGA Staphylococcus aureus MW2

100

100

1
  comGA Staphylococcus aureus N315

100

100

1