Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   HC661_RS05795 Genome accession   NZ_CP051463
Coordinates   1117418..1118074 (+) Length   218 a.a.
NCBI ID   WP_003155032.1    Uniprot ID   I2C3J8
Organism   Bacillus velezensis strain UCMB5140     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 1112418..1123074
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HC661_RS05770 (HC661_11230) oppF 1112948..1113865 (+) 918 WP_012117283.1 oligopeptide ABC transporter ATP-binding protein OppF -
  HC661_RS05775 (HC661_11240) - 1113972..1115159 (+) 1188 WP_015417212.1 putative glycoside hydrolase -
  HC661_RS05780 (HC661_11250) - 1115277..1115855 (+) 579 WP_007409110.1 GNAT family N-acetyltransferase -
  HC661_RS05785 (HC661_11260) spx 1116033..1116428 (+) 396 WP_003155034.1 transcriptional regulator Spx -
  HC661_RS05790 (HC661_11270) - 1116486..1117142 (-) 657 WP_015417213.1 TerC family protein -
  HC661_RS19575 - 1117325..1117435 (+) 111 Protein_1085 adaptor protein MecA -
  HC661_RS05795 (HC661_11280) mecA 1117418..1118074 (+) 657 WP_003155032.1 adaptor protein MecA Regulator
  HC661_RS05800 (HC661_11290) - 1118225..1119412 (+) 1188 WP_015417214.1 competence protein CoiA family protein -
  HC661_RS05805 (HC661_11300) pepF 1119615..1121444 (+) 1830 WP_007409107.1 oligoendopeptidase F Regulator
  HC661_RS05810 (HC661_11310) - 1121482..1121649 (-) 168 WP_003155026.1 hypothetical protein -
  HC661_RS05815 (HC661_11320) spxH 1121936..1122838 (-) 903 WP_015417215.1 protease adaptor protein SpxH -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25964.75 Da        Isoelectric Point: 4.1143

>NTDB_id=438397 HC661_RS05795 WP_003155032.1 1117418..1118074(+) (mecA) [Bacillus velezensis strain UCMB5140]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHDEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPADENLDALLDDFQKEEQAESREDKEQKLQFTLRFDDFEDLISLSKLNLNGIKTTLYSFEDR
YYLYADFYEQTDEEVENQLSILLEYAHESSVSIHRLEEYGKLVIADHALYTIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=438397 HC661_RS05795 WP_003155032.1 1117418..1118074(+) (mecA) [Bacillus velezensis strain UCMB5140]
ATGGAAATAGAAAGAATTAATGAGCATACTGTAAAATTTTATATGTCTTATGGTGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATCTGGTACAATCGCGAGCGCAGTGAAGAACTGTTCTGGGAAGTCATGGATGAAGTGCATGATGAAGAGGAAT
TCGCTGTCGAGGGTCCTCTTTGGATTCAGGTTCAGGCATTGGACAAAGGACTGGAAATAATCGTAACAAAAGCCCAGCTT
TCCAAGGACGGACAAAAACTCGAACTGCCGATCCCGGAAGATAAAAAACAAGAGCCGGCAGATGAAAATCTCGATGCTTT
ACTTGATGATTTCCAGAAAGAAGAGCAGGCCGAGAGCCGGGAAGATAAGGAGCAAAAGCTTCAGTTCACTTTGCGGTTCG
ATGATTTTGAGGATCTCATCTCGCTATCAAAATTGAATCTTAACGGAATCAAAACGACCCTGTATTCGTTTGAAGACCGA
TATTATTTATATGCAGATTTTTATGAGCAAACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGTTGGAGTACGCGCA
CGAATCATCAGTCAGCATTCACCGTCTTGAAGAATACGGCAAATTGGTGATCGCTGATCATGCGTTATATACAATAAAAA
AACACTTTGCATCATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I2C3J8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

89.45

100

0.895