Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   FOI11_RS03315 Genome accession   NZ_CP063369
Coordinates   722756..723412 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain 1409     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 717756..728412
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FOI11_RS03285 (FOI11_003280) dcyD 718635..719621 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  FOI11_RS03290 (FOI11_003285) tcyL 719636..720304 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  FOI11_RS03295 (FOI11_003290) tcyN 720301..721053 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  FOI11_RS03300 (FOI11_003295) sdiA 721283..722005 (+) 723 WP_001154273.1 transcriptional regulator SdiA -
  FOI11_RS03305 (FOI11_003300) yecF 722073..722297 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  FOI11_RS03310 (FOI11_003305) yecU 722284..722460 (-) 177 WP_000590344.1 protein YecU -
  FOI11_RS24995 - 722498..722614 (-) 117 WP_001302039.1 hypothetical protein -
  FOI11_RS03315 (FOI11_003310) letA 722756..723412 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  FOI11_RS03320 (FOI11_003315) uvrC 723409..725241 (+) 1833 WP_032176379.1 excinuclease ABC subunit UvrC Machinery gene
  FOI11_RS03325 (FOI11_003320) pgsA 725298..725846 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  FOI11_RS03345 (FOI11_003340) - 726545..727282 (-) 738 Protein_656 hypothetical protein -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=438102 FOI11_RS03315 WP_000611335.1 722756..723412(+) (letA) [Escherichia coli strain 1409]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=438102 FOI11_RS03315 WP_000611335.1 722756..723412(+) (letA) [Escherichia coli strain 1409]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486