Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   IN878_RS04905 Genome accession   NZ_CP063332
Coordinates   969575..970231 (-) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain BS74R-D     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 964575..975231
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  IN878_RS04875 (IN878_04880) yecA 965826..966491 (-) 666 WP_000847902.1 UPF0149 family protein YecA -
  IN878_RS04895 (IN878_04900) pgsA 967141..967689 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  IN878_RS04900 (IN878_04905) uvrC 967746..969578 (-) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  IN878_RS04905 (IN878_04910) letA 969575..970231 (-) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  IN878_RS26225 - 970373..970489 (+) 117 WP_001302039.1 hypothetical protein -
  IN878_RS04910 (IN878_04915) yecU 970527..970703 (+) 177 WP_000590347.1 protein YecU -
  IN878_RS04915 (IN878_04920) yecF 970690..970914 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  IN878_RS04920 (IN878_04925) sdiA 970982..971704 (-) 723 WP_001154287.1 transcriptional regulator SdiA -
  IN878_RS04925 (IN878_04930) tcyN 971934..972686 (-) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  IN878_RS04930 (IN878_04935) tcyL 972683..973351 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  IN878_RS04935 (IN878_04940) dcyD 973366..974352 (-) 987 WP_001128213.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=437813 IN878_RS04905 WP_000611335.1 969575..970231(-) (letA) [Escherichia coli strain BS74R-D]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=437813 IN878_RS04905 WP_000611335.1 969575..970231(-) (letA) [Escherichia coli strain BS74R-D]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
TAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCTAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486