Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   IM723_RS06915 Genome accession   NZ_CP063275
Coordinates   1336238..1336882 (-) Length   214 a.a.
NCBI ID   WP_002951384.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain DMST-H2     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1331238..1341882
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  IM723_RS06890 - 1333340..1334338 (-) 999 WP_065972436.1 NAD(P)/FAD-dependent oxidoreductase -
  IM723_RS06895 trmD 1334340..1335059 (-) 720 WP_211836830.1 tRNA (guanosine(37)-N1)-methyltransferase TrmD -
  IM723_RS06900 rimM 1335049..1335567 (-) 519 WP_011226286.1 ribosome maturation factor RimM -
  IM723_RS06915 vraR 1336238..1336882 (-) 645 WP_002951384.1 response regulator transcription factor Regulator
  IM723_RS06920 - 1336872..1337882 (-) 1011 WP_065972437.1 sensor histidine kinase -
  IM723_RS06925 liaF 1337879..1338577 (-) 699 WP_065972438.1 cell wall-active antibiotics response protein LiaF -
  IM723_RS10075 - 1338843..1338998 (-) 156 WP_244810375.1 ion channel -
  IM723_RS06935 stkP/pknB 1339635..1341506 (-) 1872 WP_014621795.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 24048.39 Da        Isoelectric Point: 4.5864

>NTDB_id=437756 IM723_RS06915 WP_002951384.1 1336238..1336882(-) (vraR) [Streptococcus thermophilus strain DMST-H2]
MSNKINVILVDDHEMVRLGLKSFLNLQGDVEVVGEAENGREGVDLALELRPDVVVMDLVMPELDGVQATLELLKEWPEAK
ILVLTSYLDNEKIYPVIEAGAKGYMLKTSSAAEILNSIRKVYRGEEAIETEVDNKIKYHDSHPNLHDDLTARERDILALL
AKGYDNQTIANELFISLKTVKTHVSNILGKLNVDDRTQAVVYAFRHHLVSQDDE

Nucleotide


Download         Length: 645 bp        

>NTDB_id=437756 IM723_RS06915 WP_002951384.1 1336238..1336882(-) (vraR) [Streptococcus thermophilus strain DMST-H2]
ATGTCGAATAAGATTAATGTAATTTTGGTAGATGACCATGAAATGGTTCGTTTAGGCCTTAAGAGTTTCTTGAATCTCCA
AGGAGATGTAGAAGTGGTTGGAGAGGCAGAAAACGGCCGTGAGGGTGTCGATCTTGCCCTGGAGCTACGACCAGATGTCG
TTGTTATGGACCTTGTTATGCCTGAGCTAGATGGTGTTCAGGCGACTTTGGAATTGCTCAAAGAATGGCCTGAAGCTAAG
ATTCTAGTTTTGACCAGCTATTTGGACAATGAAAAAATTTATCCAGTCATTGAAGCTGGCGCCAAAGGCTATATGCTTAA
AACGAGCAGTGCAGCAGAGATTCTAAATAGTATCCGTAAGGTTTACCGTGGAGAGGAAGCTATCGAAACTGAGGTAGACA
ATAAGATTAAATACCACGATAGTCACCCGAACTTACATGATGACTTGACCGCGCGCGAACGTGATATCTTAGCCCTCCTA
GCTAAAGGCTATGACAATCAAACCATTGCTAACGAACTTTTTATTTCTTTAAAAACCGTCAAGACTCATGTGTCTAATAT
CCTTGGGAAATTAAATGTTGATGACCGTACTCAGGCTGTAGTTTATGCCTTTAGACATCATCTGGTTTCACAGGATGATG
AATAA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(7-118)

Bacterial regulatory proteins, luxR family (GerE)

(149-203)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

50.485

96.262

0.486
  degU Bacillus subtilis subsp. subtilis str. 168

36.161

100

0.379