Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB4   Type   Machinery gene
Locus tag   HGI45_RS00100 Genome accession   NZ_CP051292
Coordinates   14336..16699 (+) Length   787 a.a.
NCBI ID   WP_202137118.1    Uniprot ID   -
Organism   Helicobacter pylori strain ASHA-003     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 9336..21699
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HGI45_RS00070 (HGI45_00070) groES 9356..9712 (-) 357 WP_000671949.1 co-chaperone GroES -
  HGI45_RS00075 (HGI45_00075) dnaG 9998..11677 (+) 1680 WP_202137116.1 DNA primase -
  HGI45_RS00080 (HGI45_00080) - 11674..12726 (+) 1053 WP_202137117.1 MnmA/TRMU family protein -
  HGI45_RS00085 (HGI45_00085) - 12817..13644 (+) 828 WP_001154940.1 DUF5718 family protein -
  HGI45_RS00090 (HGI45_00090) comB2 13790..14071 (+) 282 WP_001272686.1 TrbC/VirB2 family protein Machinery gene
  HGI45_RS00095 (HGI45_00095) comB3 14071..14334 (+) 264 WP_000584950.1 hypothetical protein Machinery gene
  HGI45_RS00100 (HGI45_00100) comB4 14336..16699 (+) 2364 WP_202137118.1 VirB4 family type IV secretion/conjugal transfer ATPase Machinery gene
  HGI45_RS00110 (HGI45_00110) - 17004..18344 (+) 1341 WP_202137119.1 COG3014 family protein -
  HGI45_RS00115 (HGI45_00115) cheV1 18453..19418 (+) 966 WP_202137120.1 chemotaxis protein CheV1 -
  HGI45_RS00120 (HGI45_00120) nspC 19415..20632 (+) 1218 WP_202137121.1 carboxynorspermidine decarboxylase -
  HGI45_RS00125 (HGI45_00125) lpxE 20629..21174 (-) 546 WP_237389292.1 lipid A 1-phosphatase LpxE -

Sequence

Protein


Download         Length: 787 a.a.        Molecular weight: 90250.57 Da        Isoelectric Point: 7.6515

>NTDB_id=437256 HGI45_RS00100 WP_202137118.1 14336..16699(+) (comB4) [Helicobacter pylori strain ASHA-003]
MLEKFLGAIKQKVSNYFLGALPKSYSMSEENNILGLYDEHFLLTKNENLVGILRLEGVSYTHLSTEQLQDLFTERQMALD
SLEKVVARLVVKRRKIDYKQSIQSDSQYLQAILNQFENKEVYENQYFLVLESAHSLQGVLEHKKKSFMHANRENFKDILS
YKAHFLQETFKSLEIQLKNYAPKLLSSKEVLNFYAEYINGFDLPLKPLVGGYLSDSYIASSITFEKDYFIQESFNQKTYN
RLIGIKAYESERITSIAVGALLYQETPLDIIFSIEPMSVNKTLSFLKERAKFSMSNLVKNELLEYQELVKTKRLSMQKFA
LNILIKAPSLEDLDAQTSLILGLLFKENLVGVIETFGLKGGYFSFFPERIYLNHRLRFLTSKALACLMVFERQNLGFKAN
SWGNSPLSVFKNLDYSPFLFNFHNQEVSHNNAKEIDRVNGHTLVIGATGSGKSTLISFLMMSALKYQNMRLLAFDRMQGL
YSFTEFFKGHYHDGQSFSINPFCLEPNLQNLEFLQSFFLSMFDLAPSRDKEALEDMNAISGTIKSLYETLYPKDFSLLDF
KETLKRTSSNQLGLSLEPYLNNPLFNALNDAFNSSAFLNVINLDAITQNPKDLGLLAYYLFYKILEESRKNDSGFLVFLD
EFKSYVENDLLNTKINALITQARKANGVVVLALQDIYQLSGVKNAHSFLSNMGTLILYPQKNARELKHNFNVPLSETEIS
FLENTPLYARQVLVKNLGNGSSNMIDVSLEGLGRYLKIFNSDSSHVNKVKALQKDYPTEWREKLLKS

Nucleotide


Download         Length: 2364 bp        

>NTDB_id=437256 HGI45_RS00100 WP_202137118.1 14336..16699(+) (comB4) [Helicobacter pylori strain ASHA-003]
ATGTTAGAAAAGTTTTTAGGCGCTATCAAGCAAAAAGTTTCAAATTATTTTTTAGGGGCTTTGCCTAAAAGCTATTCAAT
GAGTGAAGAAAACAACATTTTAGGCTTGTATGATGAGCATTTTTTACTCACTAAAAACGAAAACTTAGTGGGCATTCTCC
GTTTAGAGGGGGTGAGTTACACCCATTTAAGCACAGAGCAATTGCAAGATCTTTTCACTGAGCGCCAAATGGCGTTGGAT
TCTTTGGAAAAGGTCGTGGCGCGCCTTGTGGTTAAAAGGCGTAAAATTGATTATAAACAAAGCATTCAATCTGACTCTCA
ATACTTGCAAGCGATCTTGAATCAGTTTGAAAATAAAGAAGTGTATGAAAATCAGTATTTTTTGGTTTTAGAAAGCGCGC
ACTCTTTACAGGGCGTTTTAGAGCATAAGAAAAAATCTTTCATGCACGCTAATAGAGAAAATTTTAAGGATATTCTCTCT
TATAAAGCGCATTTTTTGCAAGAAACTTTTAAAAGTTTAGAAATCCAGCTCAAAAATTATGCCCCCAAACTCTTAAGCTC
TAAAGAGGTTTTGAATTTTTATGCGGAATACATTAACGGGTTTGATCTCCCTTTAAAACCCCTAGTAGGGGGGTATTTGA
GCGATAGCTATATCGCTAGTTCCATCACTTTTGAAAAAGATTATTTCATTCAAGAAAGCTTTAATCAAAAAACCTATAAC
CGCTTGATTGGCATTAAAGCTTATGAGAGCGAACGCATCACTTCTATAGCGGTGGGAGCGCTTTTATACCAAGAGACTCC
ACTAGATATTATCTTTTCCATAGAGCCTATGAGCGTCAATAAAACGCTGAGTTTTTTAAAAGAGAGGGCCAAGTTTAGCA
TGTCTAATCTCGTTAAAAACGAGCTGCTAGAATACCAAGAATTAGTCAAAACCAAACGATTATCCATGCAAAAATTCGCC
CTAAACATTCTTATCAAAGCCCCCAGTTTAGAGGATTTAGACGCTCAAACCAGCTTAATTTTAGGGCTTTTATTTAAAGA
AAACTTAGTGGGCGTTATAGAAACTTTTGGCTTGAAAGGGGGGTATTTTTCCTTTTTCCCTGAACGCATTTATTTAAACC
ACCGCTTGCGTTTTTTAACCTCTAAAGCCCTAGCGTGTTTGATGGTGTTTGAAAGGCAAAATTTAGGTTTTAAGGCTAAT
TCATGGGGGAATAGCCCTTTGAGCGTGTTTAAAAATTTGGATTATTCCCCTTTTTTATTCAATTTCCACAACCAAGAAGT
GAGCCATAATAACGCTAAAGAAATCGACAGAGTGAATGGGCATACTTTAGTTATAGGGGCAACCGGAAGCGGTAAAAGCA
CGCTGATTAGCTTTTTAATGATGAGCGCTTTGAAATACCAAAACATGCGCCTTTTAGCTTTTGACAGGATGCAAGGGCTG
TATTCTTTCACCGAATTTTTTAAAGGGCATTACCATGACGGCCAATCTTTTAGCATTAACCCCTTTTGTTTAGAGCCTAA
TTTGCAGAATTTAGAATTTTTGCAATCCTTTTTTTTGAGCATGTTCGATCTCGCCCCTTCAAGAGATAAAGAAGCCTTAG
AAGATATGAATGCGATTTCTGGCACGATTAAGAGCCTTTATGAGACCCTATACCCCAAAGATTTTAGTTTGCTGGATTTT
AAAGAAACGCTTAAAAGAACCTCATCTAACCAACTGGGCTTGAGCTTGGAGCCGTATTTGAATAACCCCCTTTTTAACGC
TTTGAATGATGCGTTCAACTCAAGCGCTTTTTTAAACGTGATAAACTTAGATGCGATCACCCAAAACCCTAAAGATTTAG
GGCTTTTAGCCTATTACTTGTTTTATAAGATCTTAGAAGAGTCTAGGAAAAACGACAGCGGCTTTTTGGTTTTTTTAGAC
GAATTTAAATCCTATGTGGAAAACGATTTGTTGAACACTAAAATCAACGCTTTAATCACGCAAGCCAGGAAAGCTAATGG
CGTGGTGGTGTTGGCTTTGCAAGACATTTACCAACTCAGCGGGGTCAAAAACGCCCATAGTTTTTTAAGCAACATGGGGA
CTCTTATTTTGTATCCGCAAAAAAACGCTAGGGAATTGAAACACAATTTCAATGTGCCTTTGAGCGAAACTGAAATTTCA
TTTTTAGAAAACACGCCTTTGTATGCCAGGCAGGTTTTAGTCAAAAATCTGGGTAACGGGAGTTCTAACATGATTGATGT
GAGTTTGGAGGGCTTGGGGCGTTATTTGAAAATCTTTAATTCAGATTCTAGTCATGTGAATAAAGTGAAAGCGTTACAAA
AAGACTACCCTACAGAGTGGCGTGAGAAACTTTTGAAGAGTTAG

Domains

Predicted by InterproScan.

FtsK/SpoIIIE family (FtsK_SpoIIIE)

(424-466)

CagE, TrbE, VirB family, component of type IV transporter system (CagE_TrbE_VirB)

(176-375)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB4 Helicobacter pylori 26695

96.569

100

0.966