Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   INP89_RS00820 Genome accession   NZ_CP063127
Coordinates   166474..168303 (+) Length   609 a.a.
NCBI ID   WP_038439602.1    Uniprot ID   -
Organism   Haemophilus influenzae strain M1C112_1     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 161474..173303
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  INP89_RS00805 (INP89_00805) msbA 162659..164422 (+) 1764 WP_012054790.1 lipid A ABC transporter ATP-binding protein/permease MsbA -
  INP89_RS00810 (INP89_00810) lpxK 164495..165493 (+) 999 WP_112083109.1 tetraacyldisaccharide 4'-kinase -
  INP89_RS00815 (INP89_00815) kdsB 165564..166328 (+) 765 WP_012054788.1 3-deoxy-manno-octulosonate cytidylyltransferase -
  INP89_RS00820 (INP89_00820) uvrC 166474..168303 (+) 1830 WP_038439602.1 excinuclease ABC subunit UvrC Machinery gene
  INP89_RS00825 (INP89_00825) - 168401..169114 (+) 714 WP_012054787.1 TerC family protein -
  INP89_RS00830 (INP89_00830) uxuA 169167..170351 (-) 1185 WP_012054786.1 mannonate dehydratase -
  INP89_RS00835 (INP89_00835) - 170371..171126 (-) 756 WP_012054785.1 FCD domain-containing protein -
  INP89_RS00840 (INP89_00840) - 171227..171499 (-) 273 WP_005672668.1 IS1595 family transposase -
  INP89_RS00845 (INP89_00845) - 171854..172699 (+) 846 WP_012054784.1 SDR family oxidoreductase -

Sequence

Protein


Download         Length: 609 a.a.        Molecular weight: 69602.50 Da        Isoelectric Point: 9.1382

>NTDB_id=436966 INP89_RS00820 WP_038439602.1 166474..168303(+) (uvrC) [Haemophilus influenzae strain M1C112_1]
MFNYKKFLADVSHEPGVYRMYDDKDQVIYVGKAKDLKKRLSSYFRKNLSSKKTEALVASIHHIDTMLTSSETEALLLEHN
FIKLYQPRYNVLLRDDKSYPFILLTKERHPRITSYRGSKKFAGEYFGPYPHAGAVRETLSLLQKLFPVRQCENSVYSNRS
RPCLQYQIGRCSAPCVQGYVSDEEYNQQVELARLFLQGKDQLVLDYLIGKMEQASRNLDFEQAARYRDQIQAVRSVIEKQ
FVSNERLDDMDIMSIAYQHGLACVQVMFIRQGKVLGNRSYFPKVPANTDLSELTETFVGQFYLQGHQGRSIPNSIIVDRQ
LAEKSELEQLLTEQAGRKVTIQESVKGDKSKYLQLAQVNAKAALNVQLKQSSRMSERYQALCDLLNLPEIKRMECFDISH
TMGNQTVASCVVFNQEGPLKSDYRRFNIEGITGGDDYAAMEQALQKRYERDLEEDKIPDIIFIDGGKGQLNRALNVFQHL
QVKWDKNRPHLIGVAKGVDRRAGQEVLIISKQDREIHLPDDSLALHLIQHIRDESHNHAISGHRKKRQKAFTQSGLETIE
GVGAKRRQALLKYLGGLQGVKKATLDEIASVPGISLKLAETIFETLKND

Nucleotide


Download         Length: 1830 bp        

>NTDB_id=436966 INP89_RS00820 WP_038439602.1 166474..168303(+) (uvrC) [Haemophilus influenzae strain M1C112_1]
ATGTTCAATTACAAAAAATTCCTCGCTGATGTCTCTCACGAACCTGGTGTTTATCGTATGTATGACGATAAAGATCAGGT
TATTTATGTTGGGAAAGCAAAGGATCTAAAAAAACGTCTTTCAAGCTATTTTCGTAAAAATCTGAGTAGTAAAAAAACAG
AGGCGTTGGTGGCATCAATTCATCATATTGACACCATGCTAACTTCATCTGAAACGGAAGCTTTACTGCTAGAGCATAAT
TTTATCAAGCTTTATCAGCCTCGCTATAACGTATTATTGCGTGATGATAAATCCTATCCATTTATTTTATTAACCAAAGA
ACGCCATCCAAGAATCACGTCCTATCGTGGGTCTAAAAAATTTGCGGGTGAATATTTCGGGCCCTATCCTCACGCAGGCG
CCGTGCGTGAAACTTTATCGCTTTTACAAAAACTTTTCCCTGTTCGACAATGTGAAAATTCCGTTTATTCCAACCGCTCT
CGTCCTTGTTTGCAATATCAAATTGGGCGTTGTTCTGCGCCTTGTGTACAGGGATATGTTTCTGATGAAGAATATAATCA
GCAAGTTGAATTAGCCCGCTTATTTTTACAAGGCAAAGATCAACTGGTGTTAGATTATTTAATCGGGAAAATGGAGCAGG
CAAGCAGAAATTTAGATTTTGAACAGGCGGCTCGTTATCGCGATCAAATTCAGGCGGTGCGTTCGGTTATTGAAAAACAA
TTTGTATCCAATGAACGTTTAGATGATATGGATATTATGTCCATTGCTTACCAACACGGTTTAGCCTGTGTACAAGTGAT
GTTTATTCGTCAAGGAAAAGTGCTAGGCAATCGCAGTTACTTCCCAAAAGTCCCTGCCAATACGGATTTATCGGAACTTA
CCGAAACTTTTGTGGGGCAATTTTATTTACAAGGTCATCAAGGGCGAAGTATCCCAAATAGTATTATTGTCGATCGTCAA
TTAGCTGAAAAATCAGAGCTTGAGCAACTTCTTACGGAGCAAGCAGGCAGAAAAGTGACGATTCAAGAAAGTGTAAAAGG
CGATAAGAGTAAATACTTACAGCTCGCACAAGTTAATGCTAAAGCGGCTTTAAATGTACAACTTAAACAATCTTCACGAA
TGTCAGAGCGTTATCAAGCGTTGTGTGATCTGTTAAATCTCCCTGAAATTAAGCGTATGGAGTGTTTCGATATAAGCCAC
ACGATGGGAAATCAAACGGTAGCATCTTGTGTTGTTTTTAATCAAGAAGGCCCACTGAAATCTGATTATCGTCGTTTTAA
TATTGAAGGCATTACTGGTGGGGATGATTATGCAGCAATGGAACAAGCGTTGCAGAAACGTTATGAGCGTGATTTAGAAG
AAGATAAAATTCCCGATATTATTTTTATTGATGGTGGAAAAGGGCAATTAAATCGTGCGCTGAACGTGTTCCAACATCTT
CAAGTAAAATGGGATAAAAATAGACCGCACTTAATTGGCGTGGCAAAAGGTGTGGATCGTCGAGCAGGGCAGGAAGTACT
GATCATCAGCAAACAAGACCGCGAAATTCATTTGCCTGATGATAGTTTGGCATTGCATTTGATTCAACACATCCGTGATG
AAAGTCATAATCACGCAATAAGCGGACACCGTAAAAAACGTCAAAAAGCCTTTACACAAAGTGGTTTAGAAACTATTGAA
GGTGTGGGGGCTAAACGTCGTCAGGCTTTACTGAAATATCTTGGTGGTTTACAAGGTGTGAAAAAGGCGACCTTAGATGA
AATAGCCTCTGTACCAGGAATTTCCCTTAAACTTGCTGAAACGATTTTTGAAACGCTCAAAAACGATTAA

Domains

Predicted by InterProScan.

Helix-hairpin-helix domain (HHH_5)

(556-607)

UvrB/uvrC motif (UVR)

(210-234)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(384-540)

GIY-YIG catalytic domain (GIY-YIG)

(15-90)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae TIGR4

37.647

97.701

0.368
  uvrC Streptococcus pneumoniae R6

37.311

97.701

0.365
  uvrC Streptococcus pneumoniae D39

37.311

97.701

0.365