Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   INP90_RS06050 Genome accession   NZ_CP063124
Coordinates   1209016..1210842 (+) Length   608 a.a.
NCBI ID   WP_197559291.1    Uniprot ID   -
Organism   Haemophilus parainfluenzae strain M1C113_1     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1204016..1215842
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  INP90_RS06030 (INP90_06035) msbA 1205244..1207007 (+) 1764 WP_197559288.1 lipid A ABC transporter ATP-binding protein/permease MsbA -
  INP90_RS06035 (INP90_06040) lpxK 1207061..1208041 (+) 981 WP_197559289.1 tetraacyldisaccharide 4'-kinase -
  INP90_RS06040 (INP90_06045) - 1208059..1208238 (+) 180 WP_049372406.1 Trm112 family protein -
  INP90_RS06045 (INP90_06050) kdsB 1208248..1209006 (+) 759 WP_197559290.1 3-deoxy-manno-octulosonate cytidylyltransferase -
  INP90_RS06050 (INP90_06055) uvrC 1209016..1210842 (+) 1827 WP_197559291.1 excinuclease ABC subunit UvrC Machinery gene
  INP90_RS06055 (INP90_06060) - 1210911..1211630 (+) 720 WP_111315515.1 TerC family protein -
  INP90_RS06060 (INP90_06065) - 1211669..1212721 (-) 1053 WP_049370160.1 ABC transporter ATP-binding protein -
  INP90_RS06065 (INP90_06070) - 1212735..1214255 (-) 1521 WP_049370161.1 ABC transporter permease -
  INP90_RS06070 (INP90_06075) - 1214340..1215338 (-) 999 WP_197559292.1 iron ABC transporter substrate-binding protein -

Sequence

Protein


Download         Length: 608 a.a.        Molecular weight: 69154.94 Da        Isoelectric Point: 8.8187

>NTDB_id=436947 INP90_RS06050 WP_197559291.1 1209016..1210842(+) (uvrC) [Haemophilus parainfluenzae strain M1C113_1]
MFDSKKFLSDVSHEPGVYRMYDDKDQVIYVGKAKDLKKRLSSYFRKNLSSKKTEALVSSIHHIDTTITSSETEALLLEHN
FIKLYQPRYNVLLRDDKSYPFILLTKERHPRITSYRGTKKIAGEYFGPYPHAGAVRETLSLMQKLFPVRQCENSVYNNRS
RPCLQYQIGRCSAPCVLGYVSDEEYNQQVELARLFLQGKDQQVLDYLIGKMEQASRDLDFEGAARYRDQIQAVRAVIEKQ
FVSNERLDDMDIMSIAYQHGLACVQVMFIRQGKVLGNRSYFPKVPANTDLSELTATFVGQFYLQGHQGRSIPNSIIVDHK
LDEKAELEALLTEQAGRKVVIQESAKGDKGKYLQLAQINAKAALATQLKQSSRMHERYQALCELLDMPEIKRMECFDISH
TMGNQTVASCVVFNQEGPLKSDYRRFNIEGITGGDDYAAMEQALKKRYDRDLDDDKIPDIIFIDGGKGQLNRALEVFHHL
NVKWDKNRPHLIGVAKGVDRRAGQEVLIISKQDREIHLPDDSLALHLIQHIRDESHNHAISGHRQKRQKAFTQSGLETIE
GVGAKRRQALLKYLGGLQGVKNATLDEIASVPGISKALAEKIFETLKS

Nucleotide


Download         Length: 1827 bp        

>NTDB_id=436947 INP90_RS06050 WP_197559291.1 1209016..1210842(+) (uvrC) [Haemophilus parainfluenzae strain M1C113_1]
ATGTTTGATTCCAAGAAGTTTCTCTCAGACGTTTCTCATGAACCTGGTGTTTATCGTATGTATGACGATAAAGATCAGGT
TATTTATGTGGGCAAAGCGAAAGATCTCAAAAAGCGACTTTCCAGCTATTTCCGCAAAAACTTAAGTAGCAAAAAAACAG
AAGCCTTGGTGTCGTCAATTCATCATATCGACACAACCATTACTTCTTCTGAAACTGAAGCGTTATTGCTTGAGCATAAC
TTTATTAAACTTTATCAGCCTCGTTATAACGTATTATTGCGAGATGATAAATCCTATCCTTTTATTTTATTGACGAAAGA
ACGTCATCCTCGTATTACCTCTTATCGCGGAACGAAAAAAATTGCAGGCGAATATTTTGGCCCTTATCCTCATGCCGGTG
CAGTGCGTGAAACCTTGTCGTTAATGCAAAAATTATTCCCTGTTCGTCAATGTGAAAATTCGGTTTATAACAATCGTTCC
CGCCCTTGTTTGCAATATCAAATCGGGCGTTGCTCAGCACCTTGTGTGCTAGGTTATGTGAGTGATGAGGAATATAACCA
ACAAGTGGAATTAGCACGATTATTTTTGCAAGGGAAAGATCAGCAAGTATTAGATTACCTCATTGGCAAAATGGAACAGG
CTAGCCGAGACTTAGATTTTGAAGGGGCAGCACGTTATCGCGATCAAATTCAAGCGGTTCGTGCAGTTATCGAAAAACAA
TTCGTATCCAATGAGCGTTTGGACGACATGGATATTATGTCTATTGCGTATCAACATGGTTTAGCTTGTGTTCAGGTGAT
GTTTATTCGTCAAGGTAAAGTATTAGGCAATCGTAGTTATTTTCCAAAAGTGCCTGCTAATACTGATTTATCTGAATTAA
CTGCGACATTTGTGGGGCAGTTTTATTTGCAAGGTCATCAGGGCAGAAGTATTCCTAATAGTATTATTGTGGATCATAAA
TTAGATGAAAAAGCGGAGCTTGAAGCCTTGTTAACTGAACAAGCCGGTAGAAAAGTAGTGATACAAGAATCGGCTAAAGG
CGATAAAGGTAAATATCTACAACTAGCGCAAATTAATGCCAAAGCGGCTTTGGCGACCCAACTCAAACAATCTTCTCGAA
TGCACGAGCGTTATCAAGCCCTTTGCGAATTGCTCGATATGCCTGAAATTAAACGTATGGAATGTTTTGATATTAGCCAT
ACGATGGGAAATCAAACCGTGGCATCTTGCGTGGTATTTAATCAAGAAGGCCCACTGAAATCAGATTATCGCCGTTTTAA
TATTGAAGGCATTACTGGCGGCGATGATTATGCCGCGATGGAGCAAGCCTTAAAGAAACGTTACGACCGCGATCTTGATG
ATGATAAAATTCCCGATATTATTTTTATTGATGGTGGTAAAGGGCAGCTTAATCGTGCCTTAGAGGTTTTTCATCACCTC
AACGTAAAATGGGATAAAAATCGACCGCACTTAATTGGTGTGGCAAAAGGTGTGGATCGTCGAGCAGGACAAGAGGTGTT
GATTATCAGCAAACAAGATCGTGAAATCCATTTGCCGGATGATAGCCTTGCACTGCATTTAATCCAACATATTCGAGATG
AAAGCCATAATCATGCGATTAGCGGTCATCGTCAAAAACGTCAAAAAGCCTTTACCCAAAGTGGATTGGAAACCATTGAA
GGGGTAGGCGCTAAACGACGCCAAGCCTTGTTGAAATATTTAGGTGGATTACAAGGTGTCAAAAATGCCACATTGGATGA
AATCGCCTCTGTACCCGGTATTTCTAAAGCGTTAGCGGAAAAGATTTTCGAGACCTTAAAAAGTTAG

Domains

Predicted by InterProScan.

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(384-540)

Helix-hairpin-helix domain (HHH_5)

(556-607)

GIY-YIG catalytic domain (GIY-YIG)

(15-90)

UvrB/uvrC motif (UVR)

(210-235)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae TIGR4

37.793

98.355

0.372
  uvrC Streptococcus pneumoniae R6

37.458

98.355

0.368
  uvrC Streptococcus pneumoniae D39

37.458

98.355

0.368