Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   LP12_RS13200 Genome accession   NC_016811
Coordinates   2954418..2955077 (-) Length   219 a.a.
NCBI ID   WP_011216518.1    Uniprot ID   -
Organism   Legionella pneumophila subsp. pneumophila ATCC 43290     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2949418..2960077
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LP12_RS13185 (lp12_2636) - 2950218..2950877 (+) 660 WP_010948343.1 hypothetical protein -
  LP12_RS13190 (lp12_2637) lcl 2951045..2952526 (+) 1482 WP_010948344.1 collagen-like adhesin Lcl -
  LP12_RS13195 (lp12_2638) uvrC 2952550..2954406 (-) 1857 WP_010948345.1 excinuclease ABC subunit UvrC -
  LP12_RS13200 (lp12_2639) letA 2954418..2955077 (-) 660 WP_011216518.1 two-component system response regulator LetA Regulator
  LP12_RS13205 (lp12_2640) phhA 2955202..2956020 (-) 819 WP_010948347.1 phenylalanine 4-monooxygenase -
  LP12_RS13210 (lp12_2641) - 2956459..2957556 (+) 1098 WP_010948348.1 competence/damage-inducible protein A -
  LP12_RS13215 (lp12_2642) cgtA 2957515..2958540 (-) 1026 WP_010948349.1 Obg family GTPase CgtA -
  LP12_RS13220 (lp12_2643) rpmA 2958755..2959033 (-) 279 WP_010948350.1 50S ribosomal protein L27 -
  LP12_RS13225 (lp12_2644) rplU 2959046..2959357 (-) 312 WP_010948351.1 50S ribosomal protein L21 -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24556.49 Da        Isoelectric Point: 5.1572

>NTDB_id=43683 LP12_RS13200 WP_011216518.1 2954418..2955077(-) (letA) [Legionella pneumophila subsp. pneumophila ATCC 43290]
MIKVLIVDDHALVRMGIRRLLEDMSDVDVVADAESGEQALAYVKTHSPDVVLLDMKMPGIDGWEVTRRLKKTNPNIKVIA
VTAICSDPLPTRVLQLGAMGYLTKESGAEEMAAAIRKVAKGEKYLSAEIAQKMAINSLQESQDSPFDLLSEREMQVMLMI
TSGMNVQDIADRLFLSSKTINGYRYRMFEKLGIKNDVELTYLAMKHRIIEHPNDLSQDD

Nucleotide


Download         Length: 660 bp        

>NTDB_id=43683 LP12_RS13200 WP_011216518.1 2954418..2955077(-) (letA) [Legionella pneumophila subsp. pneumophila ATCC 43290]
TTGATTAAAGTATTAATTGTTGATGACCATGCATTGGTTAGAATGGGCATTCGACGATTGCTTGAAGATATGTCGGATGT
TGATGTAGTTGCAGATGCTGAAAGTGGTGAGCAGGCTTTAGCCTATGTAAAAACCCACTCCCCTGATGTCGTATTATTAG
ATATGAAAATGCCTGGGATAGATGGGTGGGAAGTGACGCGTCGTTTAAAAAAAACAAACCCAAATATTAAAGTCATAGCT
GTTACAGCTATTTGCTCAGATCCTCTCCCTACTCGAGTATTGCAATTAGGTGCTATGGGATACCTTACTAAAGAGTCAGG
GGCTGAAGAAATGGCTGCCGCAATTCGTAAAGTGGCTAAAGGTGAGAAATATCTTAGTGCCGAGATAGCACAAAAAATGG
CAATTAATAGTCTTCAGGAGTCTCAGGATTCCCCTTTTGATTTATTGTCTGAAAGAGAAATGCAAGTCATGTTGATGATT
ACTAGCGGCATGAATGTACAAGACATTGCTGATAGATTATTTTTAAGTAGTAAAACCATCAATGGCTATCGATATAGGAT
GTTTGAAAAATTGGGGATTAAAAATGATGTGGAGCTTACTTATTTGGCTATGAAGCACCGCATTATTGAGCACCCCAATG
ATTTGTCACAAGATGATTAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-116)

Bacterial regulatory proteins, luxR family (GerE)

(148-203)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

99.543

100

0.995
  letA Legionella pneumophila strain ERS1305867

99.543

100

0.995

Multiple sequence alignment