Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   INP93_RS06205 Genome accession   NZ_CP063121
Coordinates   1247221..1249047 (+) Length   608 a.a.
NCBI ID   WP_197544422.1    Uniprot ID   -
Organism   Haemophilus parainfluenzae strain M1C130_2     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1242221..1254047
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  INP93_RS06185 (INP93_06185) msbA 1243465..1245213 (+) 1749 WP_005697209.1 lipid A ABC transporter ATP-binding protein/permease MsbA -
  INP93_RS06190 (INP93_06190) lpxK 1245267..1246247 (+) 981 WP_197544421.1 tetraacyldisaccharide 4'-kinase -
  INP93_RS06195 (INP93_06195) - 1246264..1246443 (+) 180 WP_049372406.1 Trm112 family protein -
  INP93_RS06200 (INP93_06200) kdsB 1246453..1247211 (+) 759 WP_049362145.1 3-deoxy-manno-octulosonate cytidylyltransferase -
  INP93_RS06205 (INP93_06205) uvrC 1247221..1249047 (+) 1827 WP_197544422.1 excinuclease ABC subunit UvrC Machinery gene
  INP93_RS06210 (INP93_06210) - 1249117..1249836 (+) 720 WP_197544423.1 TerC family protein -
  INP93_RS06215 (INP93_06215) - 1249873..1250925 (-) 1053 WP_197544424.1 ABC transporter ATP-binding protein -
  INP93_RS06220 (INP93_06220) - 1250938..1252458 (-) 1521 WP_197544425.1 ABC transporter permease -
  INP93_RS06225 (INP93_06225) - 1252542..1253540 (-) 999 WP_049365385.1 iron ABC transporter substrate-binding protein -

Sequence

Protein


Download         Length: 608 a.a.        Molecular weight: 69182.95 Da        Isoelectric Point: 8.8187

>NTDB_id=436764 INP93_RS06205 WP_197544422.1 1247221..1249047(+) (uvrC) [Haemophilus parainfluenzae strain M1C130_2]
MFDSKKFLSDVSHEPGVYRMYDDKDQVIYVGKAKDLKKRLSSYFRKNLSSKKTEALVSSIHHIDTTITSSETEALLLEHN
FIKLYQPRYNVLLRDDKSYPFILLTKERHPRITSYRGTKKITGEYFGPYPHAGAVRETLSLMQKLFPVRQCENSVYNNRS
RPCLQYQIGRCSAPCVPGYVTDEEYNQQVELARLFLQGKDQQVLDYLIGKMEQASRDLDFEGAARYRDQIQAVRAVIEKQ
FVSNERLDDMDIMSIAYQHGLACVQVMFIRQGKVLGNRSYFPKVPANTDLSELTATFVGQFYLQGHQGRSIPNSIIVDHK
LDEKAELEALLTEQAGRKVVIQESAKGDKGKYLQLAQINAKAALATQLKQSSRMHERYQALCELLDMPEIKRMECFDISH
TMGNQTVASCVVFNQEGPLKSDYRRFNIDGITGGDDYAAMEQALKKRYDRDLDEDKIPDIIFIDGGKGQLNRALEVFHHL
NVKWDKNRPHLIGVAKGVDRRAGQEVLIISKQDREIHLPDDSLALHLIQHIRDESHNHAISGHRQKRQKAFTQSGLETIE
GVGAKRRQALLKYLGGLQGVKNATLDEIASVPGISKALAEKIFETLKS

Nucleotide


Download         Length: 1827 bp        

>NTDB_id=436764 INP93_RS06205 WP_197544422.1 1247221..1249047(+) (uvrC) [Haemophilus parainfluenzae strain M1C130_2]
ATGTTTGATTCTAAAAAGTTTCTCTCTGACGTTTCTCATGAACCTGGTGTTTATCGTATGTATGACGATAAAGATCAGGT
TATTTATGTGGGCAAAGCGAAAGATCTTAAAAAGCGCCTTTCCAGCTATTTTCGAAAAAACTTAAGCAGCAAAAAAACAG
AAGCCTTGGTGTCGTCAATTCATCATATCGACACAACCATTACCTCTTCTGAAACAGAAGCATTATTGCTTGAGCATAAC
TTTATTAAACTTTATCAACCTCGTTATAACGTATTGTTGCGAGATGATAAATCCTATCCTTTTATTTTATTGACGAAAGA
ACGTCATCCTCGTATTACTTCTTATCGCGGAACGAAAAAAATTACAGGTGAGTATTTCGGGCCTTATCCTCATGCGGGGG
CGGTGCGTGAAACCTTGTCGTTAATGCAAAAATTATTCCCTGTTCGTCAATGTGAAAATTCGGTTTATAACAATCGTTCC
CGCCCTTGTTTACAATATCAAATCGGGCGTTGCTCAGCACCTTGTGTGCCAGGTTATGTGACTGATGAGGAATATAACCA
ACAAGTTGAATTAGCACGATTATTTTTGCAAGGGAAAGATCAGCAAGTATTAGATTACCTCATTGGCAAAATGGAACAGG
CGAGCCGAGACTTGGATTTTGAAGGGGCAGCGCGTTATCGTGATCAAATTCAAGCCGTTCGAGCGGTTATCGAAAAACAA
TTTGTTTCCAATGAACGTTTGGACGATATGGATATTATGTCTATTGCGTATCAGCATGGTTTAGCTTGTGTTCAGGTGAT
GTTTATTCGTCAAGGTAAAGTATTGGGCAATCGCAGTTATTTTCCAAAAGTGCCTGCTAATACAGATTTATCCGAATTAA
CAGCAACGTTTGTTGGGCAGTTTTATTTGCAAGGTCATCAGGGTAGAAGTATTCCTAATAGTATTATTGTGGATCATAAA
CTAGATGAAAAAGCTGAGCTTGAAGCCCTGTTAACTGAACAAGCCGGTCGAAAAGTAGTGATACAAGAATCTGCTAAAGG
CGATAAAGGTAAATATCTACAACTAGCGCAAATTAATGCCAAAGCAGCTTTGGCAACTCAGCTCAAACAATCTTCTCGAA
TGCACGAACGTTATCAAGCGCTTTGCGAATTGCTCGATATGCCTGAAATTAAACGTATGGAATGTTTTGATATTAGCCAT
ACGATGGGAAATCAAACCGTGGCATCTTGCGTGGTATTTAACCAAGAAGGTCCGCTGAAATCAGACTACCGCCGTTTTAA
TATTGACGGTATTACGGGGGGGGATGACTATGCTGCGATGGAGCAAGCCTTAAAGAAACGTTACGACCGCGATCTTGATG
AAGATAAAATTCCCGATATTATTTTTATTGATGGTGGTAAAGGGCAGCTTAATCGTGCCTTAGAGGTTTTTCATCATCTC
AACGTAAAATGGGATAAAAATCGACCGCACTTAATTGGTGTGGCAAAAGGTGTGGATCGTCGAGCAGGACAAGAGGTGCT
GATTATCAGCAAACAAGATCGTGAAATCCATTTGCCGGATGATAGTCTTGCACTGCATTTAATCCAACATATTCGAGATG
AAAGCCATAATCATGCAATTAGCGGCCATCGTCAAAAACGCCAAAAAGCCTTTACCCAAAGTGGTTTAGAAACCATTGAA
GGGGTAGGCGCTAAACGACGCCAAGCCTTGTTGAAATATTTAGGTGGATTACAAGGTGTCAAAAATGCCACATTGGATGA
AATCGCCTCTGTACCCGGTATTTCTAAAGCGTTAGCGGAAAAGATTTTCGAGACCTTAAAAAGTTAG

Domains

Predicted by InterProScan.

UvrB/uvrC motif (UVR)

(210-235)

GIY-YIG catalytic domain (GIY-YIG)

(15-90)

Helix-hairpin-helix domain (HHH_5)

(556-607)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(384-540)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae TIGR4

37.96

98.355

0.373
  uvrC Streptococcus pneumoniae R6

37.815

97.862

0.37
  uvrC Streptococcus pneumoniae D39

37.815

97.862

0.37