Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   INP94_RS06420 Genome accession   NZ_CP063120
Coordinates   1288052..1289878 (+) Length   608 a.a.
NCBI ID   WP_197543044.1    Uniprot ID   -
Organism   Haemophilus parainfluenzae strain M1C137_2     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1283052..1294878
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  INP94_RS06395 (INP94_06395) msbA 1283235..1284998 (+) 1764 WP_197543040.1 lipid A ABC transporter ATP-binding protein/permease MsbA -
  INP94_RS06400 (INP94_06400) lpxK 1285052..1286032 (+) 981 WP_197543041.1 tetraacyldisaccharide 4'-kinase -
  INP94_RS06405 (INP94_06405) - 1286050..1286229 (+) 180 WP_197543042.1 Trm112 family protein -
  INP94_RS06410 (INP94_06410) kdsB 1286239..1287003 (+) 765 WP_014065112.1 3-deoxy-manno-octulosonate cytidylyltransferase -
  INP94_RS06415 (INP94_06415) - 1287037..1287990 (+) 954 WP_197543043.1 hypothetical protein -
  INP94_RS06420 (INP94_06420) uvrC 1288052..1289878 (+) 1827 WP_197543044.1 excinuclease ABC subunit UvrC Machinery gene
  INP94_RS06425 (INP94_06425) - 1289947..1290666 (+) 720 WP_197543045.1 TerC family protein -
  INP94_RS06430 (INP94_06430) - 1290704..1291756 (-) 1053 WP_197543046.1 ABC transporter ATP-binding protein -
  INP94_RS06435 (INP94_06435) - 1291769..1293289 (-) 1521 WP_197543047.1 ABC transporter permease -
  INP94_RS06440 (INP94_06440) - 1293374..1294372 (-) 999 WP_197543048.1 iron ABC transporter substrate-binding protein -

Sequence

Protein


Download         Length: 608 a.a.        Molecular weight: 69179.01 Da        Isoelectric Point: 8.8187

>NTDB_id=436700 INP94_RS06420 WP_197543044.1 1288052..1289878(+) (uvrC) [Haemophilus parainfluenzae strain M1C137_2]
MFDSKKFLSDVSHEPGVYRMYDDKDQVIYVGKAKDLKKRLSSYFRKNLSSKKTEALVSSIHHIDTTITSSETEALLLEHN
FIKLYQPRYNVLLRDDKSYPFILLTKERHPRITSYRGTKKILGEYFGPYPHAGAVRETLSLMQKLFPVRQCENSVYNNRS
RPCLQYQIGRCSAPCVPGYVADEEYNQQVELARLFLQGKDQQVLDYLIGKMEQASRDLDFEGAARYRDQIQAVRAVIEKQ
FVSNERLDDMDIMSIAYQHGLACVQVMFIRQGKVLGNRSYFPKVPANTDLSELTATFVGQFYLQGHQGRSIPNSIIVDHK
LDEKAELEALLTEQAGRKVVIQESAKGDKGKYLQLAQINAKAALATQLKQSSRMHERYQALCELLDMPEIKRMECFDISH
TMGNQTVASCVVFNQEGPLKSDYRRFNIEGITGGDDYAAMEQALKKRYDRDLDEDKIPDIIFIDGGKGQLNRALEVFHHL
NVKWDKNRPHLIGVAKGVDRRAGQEVLIISKQDREIHLPDDSLALHLIQHIRDESHNHAISGHRQKRQKAFTQSGLETIE
GVGAKRRQALLKYLGGLQGVKNATLDEIASVPGISKALAEKIFETLKS

Nucleotide


Download         Length: 1827 bp        

>NTDB_id=436700 INP94_RS06420 WP_197543044.1 1288052..1289878(+) (uvrC) [Haemophilus parainfluenzae strain M1C137_2]
ATGTTTGATTCTAAAAAGTTTCTCTCAGACGTTTCTCATGAACCTGGTGTTTATCGTATGTATGACGATAAAGATCAGGT
TATTTATGTGGGCAAAGCGAAAGATCTTAAAAAGCGCCTTTCCAGCTATTTCCGAAAAAACTTAAGTAGCAAAAAAACAG
AAGCCTTGGTGTCGTCAATTCATCATATCGACACAACCATTACCTCTTCTGAAACAGAAGCATTATTGCTTGAGCATAAC
TTTATTAAGCTTTACCAACCTCGTTATAACGTATTATTGCGAGATGATAAATCCTATCCTTTTATTTTATTGACGAAAGA
ACGTCATCCTCGTATTACTTCTTATCGTGGAACGAAAAAAATTTTAGGCGAGTATTTCGGGCCTTATCCTCATGCGGGTG
CAGTGCGTGAAACCTTGTCGTTAATGCAAAAACTATTCCCTGTTCGTCAATGTGAAAATTCGGTTTATAACAATCGTTCC
CGCCCTTGTTTGCAATATCAAATCGGGCGTTGTTCCGCTCCTTGTGTGCCAGGTTATGTGGCTGATGAGGAATATAACCA
ACAAGTGGAATTAGCGCGATTATTTTTGCAAGGGAAAGATCAGCAAGTATTAGATTACCTCATTGGCAAAATGGAGCAGG
CGAGCCGAGACTTAGATTTTGAAGGTGCGGCGCGTTATCGTGACCAAATTCAAGCGGTTCGTGCGGTTATTGAAAAACAA
TTCGTATCCAATGAGCGTTTGGACGATATGGATATTATGTCTATTGCGTATCAGCACGGTTTAGCTTGTGTTCAGGTGAT
GTTTATTCGTCAAGGTAAAGTATTGGGCAACCGCAGTTATTTTCCTAAAGTACCCGCTAATACAGATTTATCCGAATTAA
CAGCAACGTTTGTTGGGCAGTTTTATTTGCAAGGTCATCAGGGCAGAAGTATCCCGAATAGTATTATTGTGGATCATAAA
TTAGATGAAAAAGCTGAGCTTGAAGCCTTGTTAACTGAACAAGCAGGTAGAAAAGTAGTGATACAGGAATCCGCTAAAGG
CGATAAAGGTAAATATCTACAACTAGCACAAATTAATGCCAAAGCGGCGTTAGCGACTCAACTTAAACAATCTTCCCGAA
TGCACGAACGTTATCAAGCCCTTTGCGAATTGCTTGATATGCCTGAAATTAAACGTATGGAATGTTTTGATATTAGTCAT
ACGATGGGGAATCAAACTGTAGCATCTTGCGTGGTATTTAATCAAGAAGGCCCACTGAAATCAGATTATCGTCGTTTTAA
TATTGAAGGCATTACTGGCGGCGATGATTATGCAGCGATGGAGCAAGCCTTAAAGAAACGTTACGACCGCGATCTTGATG
AAGATAAAATTCCCGATATTATTTTTATTGATGGCGGTAAGGGGCAGCTTAATCGAGCCTTAGAGGTTTTTCATCACCTC
AACGTGAAATGGGATAAAAATCGACCGCACTTAATTGGTGTGGCAAAAGGTGTGGATCGTCGAGCAGGACAAGAGGTGTT
GATTATCAGCAAACAAGATCGTGAGATTCATTTGCCGGATGATAGCCTTGCACTGCATTTAATCCAACATATTCGAGATG
AAAGCCATAATCATGCGATTAGCGGCCATCGTCAAAAACGCCAAAAAGCCTTTACCCAAAGCGGATTGGAAACCATTGAA
GGGGTAGGCGCTAAACGACGCCAAGCCTTGTTGAAATATTTAGGTGGATTGCAAGGTGTCAAAAATGCCACGTTGGATGA
AATCGCCTCTGTACCTGGTATTTCTAAAGCGTTAGCAGAAAAGATTTTCGAGACCTTAAAAAGTTAG

Domains

Predicted by InterProScan.

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(384-540)

Helix-hairpin-helix domain (HHH_5)

(556-607)

GIY-YIG catalytic domain (GIY-YIG)

(15-90)

UvrB/uvrC motif (UVR)

(210-235)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae TIGR4

37.96

98.355

0.373
  uvrC Streptococcus pneumoniae R6

37.625

98.355

0.37
  uvrC Streptococcus pneumoniae D39

37.625

98.355

0.37