Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   INP96_RS05810 Genome accession   NZ_CP063116
Coordinates   1170570..1172396 (+) Length   608 a.a.
NCBI ID   WP_070852999.1    Uniprot ID   -
Organism   Haemophilus parainfluenzae strain M1C146_1     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1165570..1177396
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  INP96_RS05790 (INP96_05790) msbA 1166798..1168561 (+) 1764 WP_197555470.1 lipid A ABC transporter ATP-binding protein/permease MsbA -
  INP96_RS05795 (INP96_05795) lpxK 1168615..1169595 (+) 981 WP_197555471.1 tetraacyldisaccharide 4'-kinase -
  INP96_RS05800 (INP96_05800) - 1169613..1169792 (+) 180 WP_197555472.1 Trm112 family protein -
  INP96_RS05805 (INP96_05805) kdsB 1169802..1170560 (+) 759 WP_197555473.1 3-deoxy-manno-octulosonate cytidylyltransferase -
  INP96_RS05810 (INP96_05810) uvrC 1170570..1172396 (+) 1827 WP_070852999.1 excinuclease ABC subunit UvrC Machinery gene
  INP96_RS05815 (INP96_05815) - 1172466..1173185 (+) 720 WP_197555474.1 TerC family protein -
  INP96_RS05820 (INP96_05820) - 1173221..1174273 (-) 1053 WP_197555475.1 ABC transporter ATP-binding protein -
  INP96_RS05825 (INP96_05825) - 1174286..1175806 (-) 1521 WP_197555476.1 ABC transporter permease -
  INP96_RS05830 (INP96_05830) - 1175890..1176888 (-) 999 WP_049365385.1 iron ABC transporter substrate-binding protein -

Sequence

Protein


Download         Length: 608 a.a.        Molecular weight: 69166.95 Da        Isoelectric Point: 8.8187

>NTDB_id=436577 INP96_RS05810 WP_070852999.1 1170570..1172396(+) (uvrC) [Haemophilus parainfluenzae strain M1C146_1]
MFDSKKFLSDVSHEPGVYRMYDDKDQVIYVGKAKDLKKRLSSYFRKNLSSKKTEALVSSIHHIDTTITSSETEALLLEHN
FIKLYQPRYNVLLRDDKSYPFILLTKERHPRITSYRGTKKIAGEYFGPYPHAGAVRETLSLMQKLFPVRQCENSVYNNRS
RPCLQYQIGRCSAPCVPGYVTDEEYNQQVELARLFLQGKDQQVLDYLIGKMEQASRDLDFEGAARYRDQIQAVRAVIEKQ
FVSNERLDDMDIMSIAYQHGLACVQVMFIRQGKVLGNRSYFPKVPANTDLSELTATFVGQFYLQGHQGRSIPNSIIVDHK
LDEKAELEALLTEQAGRKVVIQESAKGDKGKYLQLAQINAKAALATQLKQSSRMHERYQALCELLDMPEIKRMECFDISH
TMGNQTVASCVVFNQEGPLKSDYRRFNIEGITGGDDYAAMEQALKKRYDRDLDEDKIPDIIFIDGGKGQLNRALEVFHHL
NVKWDKNRPHLIGVAKGVDRRAGQEVLIISKQDREIHLPDDSLALHLIQHIRDESHNHAISGHRQKRQKAFTQSGLETIE
GVGAKRRQALLKYLGGLQGVKNATLDEIASVPGISKALAEKIFETLKS

Nucleotide


Download         Length: 1827 bp        

>NTDB_id=436577 INP96_RS05810 WP_070852999.1 1170570..1172396(+) (uvrC) [Haemophilus parainfluenzae strain M1C146_1]
ATGTTTGATTCCAAGAAGTTTCTCTCAGACGTTTCTCATGAACCTGGTGTTTATCGTATGTATGACGATAAAGATCAGGT
TATTTATGTGGGCAAAGCGAAAGATCTCAAAAAGCGACTCTCCAGCTATTTCCGCAAAAACTTAAGCAGCAAAAAAACAG
AAGCGTTGGTGTCGTCAATTCATCATATCGACACAACCATTACTTCTTCTGAAACTGAAGCGTTATTGCTTGAGCATAAC
TTTATTAAACTTTATCAGCCACGTTATAACGTATTATTGCGAGATGATAAATCCTATCCTTTTATTTTATTGACGAAAGA
ACGTCATCCTCGAATTACTTCTTATCGCGGAACAAAAAAAATTGCAGGCGAGTATTTCGGACCTTATCCTCATGCAGGTG
CAGTACGTGAAACCTTATCGTTAATGCAAAAATTATTCCCTGTTCGTCAATGTGAAAATTCGGTTTATAACAATCGTTCC
CGTCCTTGTTTGCAATATCAAATCGGGCGTTGCTCAGCACCTTGTGTGCCGGGGTATGTGACAGATGAAGAATATAACCA
ACAAGTGGAATTAGCACGATTATTTTTACAAGGAAAAGATCAGCAAGTATTAGATTACCTGATTGGCAAAATGGAGCAGG
CGAGCCGAGACTTAGATTTTGAAGGTGCGGCACGTTATCGAGATCAAATTCAAGCGGTTCGTGCAGTTATCGAAAAACAA
TTTGTTTCCAATGAACGTTTGGACGATATGGATATTATGTCTATTGCGTATCAACATGGTTTAGCTTGTGTTCAGGTGAT
GTTTATTCGTCAAGGTAAAGTATTAGGCAATCGTAGTTATTTTCCAAAAGTGCCTGCTAATACTGATTTATCTGAATTAA
CTGCAACATTTGTGGGGCAGTTTTATTTGCAAGGTCATCAGGGCAGAAGTATTCCTAATAGTATTATTGTGGATCATAAA
TTAGATGAAAAAGCGGAGCTTGAAGCCTTGTTAACTGAACAAGCCGGTAGAAAAGTAGTGATACAAGAATCGGCTAAAGG
CGATAAAGGTAAATATCTACAACTAGCGCAAATTAATGCCAAAGCAGCTTTGGCAACTCAACTTAAACAATCTTCCCGAA
TGCATGAGCGTTATCAAGCTCTTTGTGAGTTGCTTGATATGCCTGAAATTAAACGTATGGAATGTTTTGATATTAGCCAT
ACGATGGGAAATCAAACCGTGGCATCTTGCGTGGTCTTTAATCAAGAAGGTCCACTGAAATCAGATTATCGCCGTTTTAA
TATTGAAGGCATTACAGGTGGTGATGACTATGCCGCGATGGAGCAAGCCTTAAAGAAACGTTACGACCGCGATCTTGATG
AAGATAAAATCCCCGATATTATTTTTATTGATGGTGGTAAAGGGCAGCTTAATCGTGCCTTAGAGGTTTTTCATCACCTC
AACGTAAAATGGGATAAAAATCGACCGCACTTAATTGGTGTGGCAAAAGGTGTGGATCGTCGAGCTGGACAAGAGGTGTT
GATTATCAGCAAACAGGATCGTGAGATTCATTTGCCGGATGATAGCCTTGCGCTGCATTTAATCCAACATATTCGAGATG
AAAGCCATAATCATGCGATTAGTGGTCATCGTCAAAAACGCCAAAAAGCCTTTACCCAAAGTGGTTTAGAAACCATTGAA
GGAGTAGGCGCTAAACGACGTCAAGCCTTGTTGAAATATTTAGGTGGATTGCAAGGTGTCAAAAATGCCACATTGGATGA
GATCGCCTCAGTACCCGGTATTTCTAAAGCCTTAGCAGAAAAGATTTTCGAGACCTTAAAAAGTTAG

Domains

Predicted by InterProScan.

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(384-540)

UvrB/uvrC motif (UVR)

(210-235)

Helix-hairpin-helix domain (HHH_5)

(556-607)

GIY-YIG catalytic domain (GIY-YIG)

(15-90)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae TIGR4

37.96

98.355

0.373
  uvrC Streptococcus pneumoniae R6

37.625

98.355

0.37
  uvrC Streptococcus pneumoniae D39

37.625

98.355

0.37