Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   INP98_RS06100 Genome accession   NZ_CP063112
Coordinates   1244196..1246022 (+) Length   608 a.a.
NCBI ID   WP_197569617.1    Uniprot ID   -
Organism   Haemophilus parainfluenzae strain M1C149_1     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1239196..1251022
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  INP98_RS06080 (INP98_06075) msbA 1240422..1242185 (+) 1764 WP_197569613.1 lipid A ABC transporter ATP-binding protein/permease MsbA -
  INP98_RS06085 (INP98_06080) lpxK 1242239..1243222 (+) 984 WP_197569614.1 tetraacyldisaccharide 4'-kinase -
  INP98_RS06090 (INP98_06085) - 1243239..1243418 (+) 180 WP_197569615.1 Trm112 family protein -
  INP98_RS06095 (INP98_06090) kdsB 1243428..1244186 (+) 759 WP_197569616.1 3-deoxy-manno-octulosonate cytidylyltransferase -
  INP98_RS06100 (INP98_06095) uvrC 1244196..1246022 (+) 1827 WP_197569617.1 excinuclease ABC subunit UvrC Machinery gene
  INP98_RS06105 (INP98_06100) - 1246092..1246811 (+) 720 WP_197569618.1 TerC family protein -
  INP98_RS06110 (INP98_06105) - 1246847..1247899 (-) 1053 WP_197569619.1 ABC transporter ATP-binding protein -
  INP98_RS06115 (INP98_06110) - 1247912..1249432 (-) 1521 WP_197569620.1 ABC transporter permease -
  INP98_RS06120 (INP98_06115) - 1249526..1250524 (-) 999 WP_197569621.1 iron ABC transporter substrate-binding protein -

Sequence

Protein


Download         Length: 608 a.a.        Molecular weight: 69120.93 Da        Isoelectric Point: 8.8187

>NTDB_id=436457 INP98_RS06100 WP_197569617.1 1244196..1246022(+) (uvrC) [Haemophilus parainfluenzae strain M1C149_1]
MFDSKKFLSDVSHEPGVYRMYDDKDQVIYVGKAKDLKKRLSSYFRKNLSSKKTEALVASIHHIDTTITSSETEALLLEHN
FIKLYQPRYNVLLRDDKSYPFILLTKERHPRITSYRGTKKIAGEYFGPYPHAGAVRETLSLMQKLFPVRQCENSVYNNRS
RPCLQYQIGRCSAPCVPGYVADEEYNQQVELARLFLQGKDQQVLDYLIGKMEQASRDLDFEGAARYRDQIQAVRAVIEKQ
FVSNERLDDMDIMSIAYQHGLACVQVMFIRQGKVLGNRSYFPKVPANTDLSELTATFVGQFYLQGHQGRSIPNSIIVDHK
LDEKAELEALLTEQAGRKVVIQESAKGDKGKYLQLAQINAKAALATQLKQSSRMHERYQALCELLDMPEIKRMECFDISH
TMGNQTVASCVVFNQEGPLKSDYRRFNIEGITGGDDYAAMEQALKKRYDRDLDEDKIPDIIFIDGGKGQLNRALEVFHHL
NVKWDKNRPHLIGVAKGVDRRAGQEVLIISKQDREIHLPDDSLALHLIQHIRDESHNHAISGHRQKRQKAFTQSGLETIE
GVGAKRRQALLKYLGGLQGVKNATLDEIASVPGISKALAEKIFETLKS

Nucleotide


Download         Length: 1827 bp        

>NTDB_id=436457 INP98_RS06100 WP_197569617.1 1244196..1246022(+) (uvrC) [Haemophilus parainfluenzae strain M1C149_1]
ATGTTTGATTCCAAGAAGTTTCTCTCAGACGTTTCTCATGAACCTGGTGTTTATCGTATGTATGACGATAAAGATCAGGT
TATTTATGTGGGCAAAGCGAAAGATCTCAAAAAGCGACTTTCCAGCTATTTCCGCAAAAACTTAAGCAGCAAAAAAACAG
AAGCCTTGGTGGCATCAATTCATCATATTGATACAACCATTACTTCTTCTGAAACCGAAGCATTATTGCTTGAGCATAAC
TTTATTAAACTTTACCAACCTCGTTATAACGTATTATTGCGAGATGATAAATCCTATCCTTTTATTTTACTGACGAAAGA
ACGTCATCCTCGTATTACTTCTTATCGTGGCACAAAAAAAATTGCAGGCGAATATTTCGGACCTTACCCTCATGCCGGTG
CAGTGCGTGAAACCTTGTCGTTAATGCAAAAATTATTCCCTGTTCGTCAATGTGAAAATTCAGTTTATAACAATCGTTCC
CGCCCTTGTTTGCAATATCAAATCGGGCGTTGTTCTGCTCCTTGTGTACCAGGTTATGTGGCTGATGAGGAATATAACCA
ACAAGTTGAATTAGCGCGATTATTTTTGCAAGGGAAAGATCAGCAAGTATTAGATTATCTCATTGGCAAAATGGAGCAGG
CGAGCCGAGACTTGGATTTTGAAGGTGCGGCACGTTATCGAGATCAAATTCAAGCAGTTCGTGCAGTTATCGAAAAACAA
TTTGTTTCCAATGAACGTTTGGACGACATGGATATTATGTCTATTGCGTATCAGCACGGTTTAGCTTGTGTTCAGGTGAT
GTTTATTCGTCAAGGCAAAGTATTGGGCAATCGCAGTTATTTTCCGAAAGTGCCTGCTAATACAGATTTATCCGAATTAA
CGGCAACGTTTGTTGGGCAGTTTTATTTGCAAGGCCATCAAGGCAGAAGTATCCCTAATAGTATTATTGTGGATCATAAA
TTAGATGAAAAAGCGGAGCTTGAAGCCTTATTAACGGAACAAGCTGGCCGAAAAGTGGTGATACAAGAATCCGCTAAAGG
CGATAAAGGTAAATATCTACAACTAGCACAAATTAATGCCAAAGCGGCGTTAGCGACTCAACTTAAACAATCTTCCCGAA
TGCACGAACGTTATCAAGCTCTTTGCGAATTGCTCGATATGCCTGAAATTAAACGTATGGAATGTTTTGATATTAGCCAT
ACGATGGGGAATCAAACCGTGGCATCTTGCGTGGTATTTAATCAAGAAGGTCCACTGAAATCAGATTATCGCCGTTTTAA
TATTGAAGGAATTACTGGCGGCGATGATTATGCCGCGATGGAGCAAGCCTTAAAGAAACGTTACGACCGCGATCTTGATG
AAGATAAAATCCCCGATATTATTTTTATTGATGGTGGTAAAGGGCAGCTTAATCGTGCCTTAGAGGTTTTTCATCACCTC
AACGTAAAATGGGATAAAAATCGACCGCACTTAATTGGTGTCGCAAAAGGTGTGGATCGTCGAGCAGGACAAGAAGTGTT
GATTATCAGCAAACAAGATCGTGAGATTCACTTGCCGGATGATAGCCTTGCACTGCATTTAATCCAACATATTCGAGATG
AAAGCCATAATCATGCAATTAGTGGTCATCGTCAAAAACGCCAAAAAGCCTTTACCCAAAGTGGTTTAGAAACCATTGAA
GGGGTGGGAGCAAAACGACGCCAAGCCTTGTTGAAATATTTAGGTGGATTACAAGGTGTCAAAAATGCCACATTGGATGA
AATCGCCTCTGTACCCGGTATTTCTAAAGCGTTAGCAGAAAAGATTTTCGAGACCTTAAAAAGTTAG

Domains

Predicted by InterProScan.

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(384-540)

GIY-YIG catalytic domain (GIY-YIG)

(15-90)

Helix-hairpin-helix domain (HHH_5)

(556-607)

UvrB/uvrC motif (UVR)

(210-235)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae TIGR4

37.793

98.355

0.372
  uvrC Streptococcus pneumoniae R6

37.458

98.355

0.368
  uvrC Streptococcus pneumoniae D39

37.458

98.355

0.368